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John Schoggins

@jschoggins.bsky.social

Professor curious about how mammals 🐵🦇 🐭 fight viruses🦠Devote inordinate amounts of time to yoga, breadmaking, coffee. Views my own.

656 Followers  |  100 Following  |  2 Posts  |  Joined: 23.10.2023  |  1.4923

Latest posts by jschoggins.bsky.social on Bluesky

Very little here

The OG is Geiss/Sen 2001 microarray - polyIC in IFN-defective cells PMID:11487589

We did microarray of lenti-cGAS (IRF3 trigger, like dsRNA) in STAT1-KO cells 2014 PMID:24284630

Irving/Wang: RNA-Seq of polyIC in IFNAR2 KO bat cells, they saw IRF1/7 signature 2020 PMID:33147460

21.05.2025 17:36 — 👍 2    🔁 0    💬 1    📌 0
Preview
Old cytokine, new tricks: A refined model of interferon’s antiviral activity Interferon is a central component of the vertebrate antiviral immune response, thought to act through induction of hundreds of interferon-stimulated genes, with some redundancy. This Perspective highl...

Out now! A fresh perspective on interferon-mediated antiviral activity -- How many ISGs does it take to inhibit a virus? Perhaps far fewer than we think.

dx.plos.org/10.1371/jour...

09.05.2025 15:07 — 👍 43    🔁 13    💬 0    📌 0

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