Emmajay Sutherland

Hi Jochen! Using Glycounter (from RRG), we can classify MS/MS scans as 'likely glyco' from the presence of >8 oxonium ions. Here, NP+MAX yields around 60% of MS/MS scans with oxonium ions whereas neat plasma (NP0) has 4%.

Can nanoparticles help us probe the glycoproteome?

The new pre-print from @riley-research.bsky.social seeks to answer this question using the Proteograph technology from Seer Inc.

Check out this lovely study on glycoproteins NP-enriched from biofluids here: chemrxiv.org/engage/chemr...

@riley-research.bsky.social had a great time catching up with local research at the Cascadia Proteomics Symposium last week. The lineup featured talks from Katie Kothlow and Haley Schramm, and a lightning talk/poster from @emmajays.bsky.social

Congrats to Emmajay for her 2nd-place poster award too!

It was great to meet you yesterday! 😊 It was nice, if unexpected, to hear a friendly familiar accent

Had an amazing time at the Glycobiology Gordon Research Seminar and Conference in Italy! 🇮🇹 As a first-time attendee, I appreciated meeting so many incredible scientists from across the world. We spent the days talking about carbohydrates, and the nights eating them. 🍝 #Glycobiology #Glycotime

GlyCounter (and pre-print) from the @riley-research.bsky.social is now out to help inspect raw MS data for glycan-specific ions.

Congrats to first author Katie Kothlow for leading this and to all RRG members who helped test GlyCounter's utility for numerous datasets! This was a great team effort.

Great talk yesterday!! 👏

A Special Software Issue in Celebration of Margaret Dayhoff’s 100th Birthday

Today we celebrate the 100th birthday of Margaret Dayhoff, founder of bioinformatics and creator of the first sequence databases. Her legacy inspires generations of scientists in bioinformatics, proteomics, and computational biology.

bit.ly/4hmTdLl

#WomenInScience #Bioinformatics #Proteomics

As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine HPV can cause a variety of cancers, including cervical. New mortality data for women under 25 point to the success of the HPV vaccine.

A recent study found that cervical cancer deaths in young women have plummeted since the introduction of the human papillomavirus vaccine.

The erosion of trust in science & scientists — sometimes due to complex social/historical factors but often deliberately perpetrated by charlatans — has tragic, deadly consequences, and, if unchecked, is an existential threat to society.

I am excited to discuss our efforts in @riley-research.bsky.social to help streamline glycoproteomics methods at the @glygen.bsky.social webinar next week!

Despite current events, @riley-research.bsky.social enjoyed @us-hupo.bsky.social last week!

Connecting w/ colleagues was an antidote for the frustration that occupies a lot of my brain space these days

Thanks for the continual motivation to pursue good science and support scientists however we can

My favorite takeaway from #USHUPO2025 so far?! Building a business is not too different from building a lab. Huge thanks to @lindsaykpino.com & @nmriley.bsky.social for hosting a phenomenal workshop on the business of starting a lab!!!

Happy International Day of Women in Science. The National Science Foundation’s list of flagged words includes both “Women” and “Female.”

The final chapter of my PhD thesis is officially published!😄 It's a true reflection of collaborative research and I can't thank my PhD supervisor, Clarissa Melo Czekster, enough. Of course, the figures feature the most amount of pink probably seen in a research journal so please enjoy! rdcu.be/d7owS

The heterogeneity of HeLa cell-lines undermines reproducibility.

HeLa cells were obtained without informed consent.

==> Researchers should avoid using HeLa cells unless required by a special justification.

Curious about artificial deamidation? Check out our updated preprint! tinyurl.com/ms6fz3sn
Now with PBS as a 6th buffer + new K562 data + N-terminal Q -> pyro-Glu investigations.

Take home message: Zwitterionic buffers like HEPES minimize unwanted artifacts!

@riley-research.bsky.social

Just let me be a scientist:
The experienced, highly qualified postdoc is a valuable resource.

PDF download
www.embopress.org/doi/epdf/10....

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

Check out this UW highlight of RRG member @jacobrussell02.bsky.social and his path to graduate school as a first-generation student! Way to go, Jacob!

artsci.washington.edu/news/firstge...

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️

So how can we ever achieve #gender #equality?

We discuss various strategies in this #Cell Commentary

#WomeninSTEM

www.cell.com/cell/fulltex...
🧵 1/

I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅

#sciart #blender3d #biocatalysis

Riley Research Group at UW - Useful Links Riley Research Group GitHub University of Washington's Proteomics Resource (UWPR) Human Glycoproteomics Initiative (HGI) via HUPO News in Proteomics Research blog by Dr. Ben Orsburn Inclusion in Chemi...

We updated some conferences of interest on the Useful Links page on our website:

www.riley-research.com/useful-links

We have yet to really advertise it, but it is a complication of resources we frequent for #TeamMassSpec, #glycotime, conferences, and more.

Hopefully others can find it useful too!

🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov

The unofficial FeMS starter pack (until they join us on Bluesky :) anyway. If you're a woman working with a mass spectrometer please ask to be added! All women are welcome!

go.bsky.app/PUwu7fr

First post on Bluesky, let’s share some websites offering many free illustrations for scientific figures 🖼️ 🧪 🌍 :

scidraw.io

bioart.niaid.nih.gov

www.phylopic.org

More well known but very nice though: www.freepik.com

A few more letters... and we can finally write amino acid sequence with protein structure encoded by amino acid sequence? 🧬🤔😀

@chrisfrank662.bsky.social , Dominik Schiwietz, Lara Fuss, Hendrik Dietz
www.biorxiv.org/content/10.1...

Congrats on your hard work!! 👏