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@tomknightsynbio.bsky.social

Engineer of stuff that is alive or computes.

1,478 Followers  |  3,836 Following  |  27 Posts  |  Joined: 30.07.2023  |  2.0618

Latest posts by tomknightsynbio.bsky.social on Bluesky

Journalists keep asking me, baffled, “What’s the Trump administration really trying to do to the science agencies?”

So I say “They are trying to destroy them. Cut off their funding, ruin their facilities, harass their staff into leaving.”

It’s not reform, and it never was. It’s destruction.

24.06.2025 22:34 — 👍 1231    🔁 507    💬 29    📌 30

Crabz.

22.06.2025 13:42 — 👍 4    🔁 0    💬 0    📌 0

Exactly. We need a shadow ACIP committee that will provide us with real information. Let the RFK group do its worst, I'd listen the shadow committee.

11.06.2025 03:14 — 👍 12    🔁 1    💬 1    📌 0

Right. And then to discover that the article you really want to read has been ripped out of the only copy. Or that your library doesn't subscribe to THAT journal. Of course, there would be books, which is more than I can say about current university libraries.

06.06.2025 22:51 — 👍 2    🔁 0    💬 0    📌 0
 quote on a dark blue and purple background from Sudip S. Parikh, CEO of the American Association for the Advancement of Science (AAAS), criticizing proposed cuts to science funding in the FY26 U.S. federal budget. The quote reads:

“If enacted, the FY26 budget request would end America’s global scientific leadership. The cuts to science would imperil our nation’s future health, security and prosperity. This budget proposal stands in stark contrast to the President’s call for a renewed commitment to American scientific leadership. Congress has demonstrated a bipartisan commitment to investment in research and must do so again to answer the President’s call.”
The quote is attributed to Sudip S. Parikh, CEO of AAAS and Executive Publisher of the Science family of journals. The AAAS logo appears at the bottom right.

quote on a dark blue and purple background from Sudip S. Parikh, CEO of the American Association for the Advancement of Science (AAAS), criticizing proposed cuts to science funding in the FY26 U.S. federal budget. The quote reads: “If enacted, the FY26 budget request would end America’s global scientific leadership. The cuts to science would imperil our nation’s future health, security and prosperity. This budget proposal stands in stark contrast to the President’s call for a renewed commitment to American scientific leadership. Congress has demonstrated a bipartisan commitment to investment in research and must do so again to answer the President’s call.” The quote is attributed to Sudip S. Parikh, CEO of AAAS and Executive Publisher of the Science family of journals. The AAAS logo appears at the bottom right.

I don't think anyone outside of universities, pharma and biotech, independent research institutions have any idea of what is happening right now. If you haven't sounded the alarm among your friends, family and colleagues, now is the time to do it.

31.05.2025 11:25 — 👍 2864    🔁 1518    💬 63    📌 51

Yeah, on stuff like inventing the Internet, and GPS. Who needs that stuff.

21.05.2025 20:37 — 👍 0    🔁 0    💬 1    📌 0

Crabz

20.05.2025 16:19 — 👍 1    🔁 0    💬 0    📌 0
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If a foreign adversary snuck into our Federal budget and cut science research and education the way we’re cutting it ourselves — strategically undermining America’s long-term health, wealth, and security — we would likely consider it an act of war.

19.05.2025 19:36 — 👍 33749    🔁 8710    💬 1192    📌 544

Crabz

07.05.2025 13:45 — 👍 3    🔁 0    💬 0    📌 0
The Mother of All Demos
YouTube video by Stanford The Mother of All Demos

Some of these innovations were directly funded. Others build upon basic research funding by the US government. If you haven’t seen Engelbart’s 1969 “mother of all demos” (where he introduces the mouse, word processor, collab editing, video conf, etc.), watch it: www.youtube.com/watch?v=JQ8Z...

04.05.2025 18:01 — 👍 337    🔁 69    💬 2    📌 3

returning to the Red Sea to spawn is an essential and beautiful part of the Super Hornet life cycle

28.04.2025 20:34 — 👍 313    🔁 38    💬 6    📌 1

Hot take: the only true metric of human progress is the global reduction of suffering. Any technological advancement that does not work in service to this is a lateral step, not forward progress. I don't care if we get to Mars, when rampant famine and disease and poverty remain unsolved for.

11.03.2025 15:18 — 👍 52    🔁 16    💬 2    📌 0

Your presence here will make it better. Be here, not there.

10.03.2025 17:06 — 👍 7    🔁 0    💬 0    📌 0
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This is why your lab automation sucks

06.03.2025 14:52 — 👍 24    🔁 5    💬 2    📌 2
Preview
We're Partnering with HaDEA in an Up-to-€24 Million Consortium Project to Deliver Next-Generation ‘Agnostic Diagnostics’ for Respiratory Viruses at the Point of Care | Ginkgo Biosecurity Headquartered in Boston, Ginkgo Bioworks uses the most advanced technology on the planet—biology—to grow better products. Our cell programming platform enables the growth of biotechnology across diver...

Today, we're thrilled to announce RANGER: RApid Next Generation Sequencing for Effective Medical Response, a consortium project supported by the European Health and Digital Executive Agency.

biosecurity.ginkgo.bio/resources/bl...

20.02.2025 13:29 — 👍 7    🔁 2    💬 0    📌 1

This is exactly right, I’ve said it 1,000 times, and @schumer.senate.gov and @schatz.bsky.social and @warren.senate.gov need to wake TF up and understand it:

These are abnormal times, the media isn’t covering things as abnormal, and that’s b/c Dem Senators are not ACTING like things are abnormal.

14.02.2025 14:05 — 👍 859    🔁 212    💬 7    📌 5

Your comment would be more compelling if you knew the difference between 'affect' and 'effect.' Not true, of courrse.

12.02.2025 01:30 — 👍 0    🔁 0    💬 0    📌 0

I love Brother P-Touch labels. Many colors, many widths. With the laptop driven version, it will automatically include initials and date: print one for the tube, one for your notebook, saves grief when you find a mystery tube in the freezer. Barcodes too.

11.02.2025 19:47 — 👍 1    🔁 0    💬 0    📌 0

How Ironic that on the International Day of Women and Girls in Science, Woman's portraits have been taken down at NIH and Women is a forbidden word that if found in your NSF grant could get it revoked. #womeninstem

11.02.2025 13:20 — 👍 97    🔁 41    💬 0    📌 2
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Happy International Women and Girls in Science Day. I celebrate Emily Noether, capturing the remarkable relationship between conservation and symmetry in Noether's theorem. Einstein said she was a "creative mathematical genius."

11.02.2025 16:52 — 👍 12    🔁 8    💬 0    📌 0

why do people still post their papers on X? I'm trying to find papers to read and it seems BlueSky doesn't propagate papers as much as X or maybe because people still post their new papers on X instead of BlueSky? Because I always find myself wander over there to find relevant papers.

08.02.2025 14:49 — 👍 2    🔁 1    💬 1    📌 0
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Engineering Biology Club: where the pizza is hot, the conversations are fascinating and the Os are GM'd

Join us this Thursday night (Feb 6) in the Boston Seaport to meet people who build tools for building biology
www.ginkgo.bio/events/engin...

04.02.2025 15:10 — 👍 6    🔁 2    💬 0    📌 0

DEXTROROTATORY ONLY

29.01.2025 17:27 — 👍 6    🔁 3    💬 1    📌 0

When I started research, I. used science citation index to look for more recent papers referencing a relevant one. In print, large volumes, yearly To save effort, collated to every. decade.

27.01.2025 20:00 — 👍 1    🔁 0    💬 0    📌 0

If someone genuinely believes that we're in a peer-level competition with Beijing, it is utterly foolish to cancel NIH and other research efforts primarily out of a Vought-driven ideological mission to terrify civil servants. It's utterly counterproductive.

23.01.2025 02:55 — 👍 2057    🔁 295    💬 34    📌 22
Preview
Starter packs BIOLOGY Ecology Macroecology https://go.bsky.app/GBn9pNZ Global ecology https://go.bsky.app/V6tN4cv Trait based ecology and evolution https://go.bsky.app/PThMXeX Invasion biology https://go.b...

hey everyone! i made a list of some useful starter packs (primarily biology/earth sciences with a few bonus things thrown in) to share with friends who have joined bsky in the last week and thought it may be useful for some people here too! 🌍🧪 #SciSky #BioSky docs.google.com/document/d/1...

11.11.2024 17:41 — 👍 731    🔁 389    💬 78    📌 38
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Enjoy the last day before tomorrow. Then four years…

19.01.2025 17:32 — 👍 37013    🔁 4932    💬 558    📌 227

This is one of the reasons why "logic design" for synthetic biology is not very interesting. Everything happens at once. It's much closer to an analog computer than a digital one.

19.01.2025 22:07 — 👍 7    🔁 1    💬 0    📌 0

Only alpha-male bro mammoths.

17.01.2025 01:15 — 👍 1    🔁 0    💬 0    📌 0
Preview
Assembly of BioBrick Standard Biological Parts Using Three Antibiotic Assembly An underlying goal of synthetic biology is to make the process of engineering biological systems easier and more reliable. In support of this goal, we…

Our experience shows that CCMB80 transformation works substantially better. See the protocol here: www.sciencedirect.com/science/arti...

16.01.2025 00:14 — 👍 1    🔁 1    💬 0    📌 0

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