Djoser Genomics

Djoser’s Bulk RNAseq Tutorial Codex A beginner friendly bulk RNAseq tutorial series told through step by step guides and inspired by ancient Egyptian History.

🧬 Introducing the Bulk RNA-seq Tutorial Codex.

A step-by-step series where I guide you through real transcriptomics analysis, one scroll at a time.

Check out the blog post and follow the codex 👉 djosergenomics.github.io/Bulk-RNAseq-...

#Bioinformatics #RNAseq #scicomm

I'm planning on making a series of mini blog tutorials on bulk RNAseq, they'll be beginner friendly to help someone who's just starting.

I'm also planning to theme it around ancient Egypt just like Djoser ;D

So stay tuned!

#Bioinfomatics #RNAseq

a cartoon character is surrounded by cats and the caption says when someone asks you what your dream job is ALT: a cartoon character is surrounded by cats and the caption says when someone asks you what your dream job is

Only a few days left to apply to join our lab and do exciting senescence research at the University of Cambridge Cancer Research UK Cambridge Institute @cruk-ci.bsky.social @cam.ac.uk 🧪🧬

You can also send informal enquiries (info below):

www.jobs.cam.ac.uk/job/52026/
www.jobs.cam.ac.uk/job/52027/

a yellow sign that says we 're hiring ALT: a yellow sign that says we 're hiring

Spread the news! We are excited to expand our research team, working on cellular senescence, at the Cancer Research UK Cambridge Institute, University of Cambridge.

jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/

Software Developer In this role, you will have the opportunity to develop domain area expertise in human genetics while working with a modern technology stack. You will design, develop and support the DECIPHER platform,...

🧬💻 We're hiring a #Software #Developer @emblebi.bsky.social! Join the @deciphergenomics.bsky.social team building tools for global rare disease diagnosis & research. Work that matters, in a collaborative environment.
👉 Apply: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
⏰ Deadline: 10 August

Discovering Mutations in fisheries-induced Selection of Zebrafish Zebrafish Variant Calling Training Project

🚀New Blog Post!

Just finished a training project on variant calling using zebrafish data from @uofglasgow.bsky.social study on fisheries selection (PRJNA630223)

Walked through the full pipeline: QC → alignment → variant calling → VEP annotation

#Genomics #Zebrafish #Bioinformatics #VariantCalling

📚Looking for some textbooks or reviews for learning genomics, gene editing, and molecular biology.

Trying to build a solid foundation, Any recommendations?

Aedes albopictus (asian tiger mosquito)

🦟 Bioinformatics Research Scientist position open in my lab in Nice (FR) to study Aedes mosquito retrotransposons & their interactions with arboviruses collab w/ @salehlabparis.bsky.social & @lambrechtslab.bsky.social
Apply: euraxess.ec.europa.eu/jobs/359830
Please boost! #ArboRetro #Bioinformatics

Exciting news! I am launching the Lab of Polymicrobial Interaction & Evolution at IPMB at Academia Sinica (ipmb.sinica.edu.tw/en)! 🎉Our brand-new website is live: (www.labofpie.org). Check the lab of PIE out!!🥧🎈

Welcome! 👋

I had a roadmap for biology -> computation. What about the reverse?

Many with a computer science background are asking: where should they start to learn biology?

📚Looking for some textbooks or reviews for learning genomics, gene editing, and molecular biology.

Trying to build a solid foundation, Any recommendations?

I learned how to read .vcf files, predict mutation effects with VEP, and rank mutation damage using SIFT & PolyPhen. 🥳

Will be diving in real zebrafish datasets soon 🔥

#genomics #bioinformatics #mutations

Schematic of the linked paper. AdvillinCre; TurboIDfl/fl mouse was used to biotylinate proteins in advillin+ cells (ie. sensory neurons), represented by stars in the schema, which were then enriched (eppendorf clipart) and put into a mass spectrometry (DIA-PASEF) to generate a neuronal-enriched proteome

Happy preprint day! We have a new transgenic & some sensory neuron compartment proteomics to share #TeamMassSpec

www.biorxiv.org/content/10.1...

I just learned how to navigate the ensemble genome browser, and I am very happy I tackled this, cuz it always looked so complicated from afar :D

Now diving into variant calling in Zebrafish (since its quite common), Let’s see what we find!

#genomics #bioinformatics #ensembl

Are you an early-career researcher working on the computational analysis of population-level human genetics data? We want to hear from you about if, how, and why you use population descriptors in your research! Fill out our short survey: forms.gle/SCiNUq71wgi5... 🧬💻🧪

🧵🦠🖥️🧬🧪
Please RePost 🙏

We just released reference genomes for another 250 strains to the ATCC Genome Portal (genomes.ATCC.org)! We now have assemblies for

_5,750 microbial genomes_

AND

all assemblies w/ @nanoporetech.com data will include DNA methylation profiles too (details👇)

#genomics 1/

🚨 New preprint alert! 🚨

We've just posted our latest work on Stony Coral Tissue Loss Disease. Using metagenomics, we look at microbial dynamics in infected corals 🧬🌊🪸

📄 Read it here: www.biorxiv.org/content/10.1...

#CoralReefs #Microbiome #Metagenomics #ViralEcology #CoralDisease #preprint

⚙️ Back to Training!

This time, I’m diving into Genomics & Variant Calling.
I’ll share some insights throughout my learning process and present some of my findings 🔍

This time I'll be going with a Marine Theme 🐟

Stay tuned.

#Bioinformatics #Genomics #Variants #Mutation #Marine #Fish

Hey 👋 #ASMicrobe! If you’re into microbial genomics - stop by during the poster session and chat with Scott Nguyen from my team from ATCC. He’s been working on a whole range of interesting microbial species 🦠many of them have never been sequenced before by anyone.

Please RePost🙏 🧪 🧬🖥️

Automated metadata curation with human-level accuracy, dataset-wide scale, and traceable quality.

Our Agentic AI system extracted 23+ metadata fields with 93% recall from GEO, papers, and supplementary files across 211 studies.

@1001shady.bsky.social

This looks super helpful!
Looking forward to reading it.

If EMBL-EBI managed data resources have ever saved you time & effort, this is your chance to give back!

Fill in a 15-minute survey to help us:
🌍Demonstrate the real-world impact of our resources
🤓Understand your needs
🌟Secure continued funding

Closes 16 July
www.surveymonkey.com/r/QGFMBH8?ch...

A multi-omic meta-analysis reveals novel mechanisms of insecticide resistance in malaria vectors - Communications Biology Multi-omic meta-analysis identifies insecticide resistance mechanisms in Anopheles vectors, highlighting convergent gene expression, purifying selection on highly expressed genes, and offering a tool ...

Pleased to see this in print! We integrate published transcriptomic and WGS data to identify novel mechanisms of resistance across the major Anopheles vectors. We also present, AnoExpress, a tool that allows users to explore and analyse the transcriptomic dataset 🧬 🖥️

www.nature.com/articles/s42...

This Looks Great. I’ve been learning a lot about transcriptomics lately but gone deep into spatial data yet. would love to try something like STIM down the road.
Thanks for sharing this!

Djoser’s 2025 Declaration Djoser Genomics began as a personal initiative to learn bioinformatics and computational biology in public. What started as an accountability tool has since evolved into something more: a serious, lon...

Check out Djoser's 2025 Declaration.

A yearly roadmap of goals, dreams, and open science vision, all driven by a bioinformatics initiative.

🌐 djosergenomics.github.io/Djoser-2025-...

#bioinformatics #openscience #DHPTA

Introducing DHPTA: A Host-Pathogen Transcriptomic Atlas for Microbial Diseases Today, I’m proud to announce the launch of DHPTA – Djoser’s Host-Pathogen Transcriptomic Atlas – a curated and reanalyzed collection of public RNAseq datasets capturing host transcriptomic responses t...

🚀 Introducing DHPTA: Djoser's Host-Pathogen Transcriptomic Atlas!

🧬 A curated collection of reanalyzed RNAseq datasets capturing human responses to microbial infections.

✨ I am excited to build this new project and watch it grow

djosergenomics.github.io/Introducing-...

#DHPTA #Transcriptomics

When Heart Disease Meets the Nervous System: Uncovering Immune Signatures in the Superior Cervical Ganglion Djoser Genomics: Advancing Transcriptomics & Bioinformatics, One Step at a Time

Broke down the key findings, plots, and major themes from the SCG reanalysis into a blog post for anyone not up for the full RNAseq reanalysis preprint 🖥️🧬

Read it here: djosergenomics.github.io/Human-SCG-RN...

#bioinformatics #rnaSeq #transcriptomics

A major milestone: my first RNAseq preprint is now live on bioRxiv 🎉🎊

I reanalyzed public data from the human SCG to uncover neuroimmune signatures during cardiac disease.🧬🖥️

This was an awesome learning experience and I am excited use everything I learned for new project ideas :D.

#Bioinformatics