Claudia Alvarez Carreño

Protein Structure Evolution Seminar November 11, 5pm CET Title: AI-Powered Classification and Discovery Across the Protein Universe Speaker: Joana Pereira Organized by: Claudia Alvarez Carreno, Zachary Ardern, Lars Eicholt, Carolina Sanchez-Rocha, Sergio Romero-Romero and MD. Hassan Uz-Zaman

The next ProSE Seminar will be given by Joana Pereira @joanampereira.bsky.social (VIB, KU Leuven)
🗓️ November 11th, 5pm CET

Registration is now open: tinyurl.com/prose-seminar2
Please share!

Join our next ProSe seminar 11th November 5PM CET and follow us @proteinstructure.bsky.social!

Protein Structure Evolution (ProSe) Seminar is now on BlueSky! Every 2nd Tuesday, 4PM GMT.

Sign-Up: tinyurl.com/prose-seminar2

Organized by Claudia Alvarez Carreño, Zachary Ardern, Lars Eicholt, Carolina Sanchez-Rocha,
Sergio Romero Romero and Md. Hassan Uz-Zaman.

I'll be featured at the outreach event of the Science Café in Nijmegen 🇳🇱, talking about astrochemistry and the origins of life and its building blocks in space and on early Earth.
Stop by if you're in the area on Thu, Oct. 23, 7.45 PM. Admission is FREE, and there will be jazz! 🎶🎷🌌🔭☄🦠

596_25_LS_ESB_R1 Reference: 596_25_LS_ESB_R1 Job title: PhD student in computational biophysics and machine learning (R1, FPI)   About BSC   The Barcelona Supercomputing Center - Centro Nacion

Last week to apply to join our recently created lab as a PhD Student!
Join us to research about protein computational biophysics, evolution, machine learning , and human mutations!
Description and link to apply here:
www.bsc.es/join-us/job-...

The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU):

Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t”
Date: October 14th, 5 pm CET
Registration link: tinyurl.com/prose-seminar2

How does catalysis emerge from non-catalytic domains?

In our new paper, we show that catalytic activity can arise without conserved active-site residues — through multimerization and electrostatic features instead.

A striking case of catalysis evolving from binding.

The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU):

Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t”
Date: October 14th, 5 pm CET
Registration link: tinyurl.com/prose-seminar2

Caribbean coral reefs are threatened by rising seas Modelling suggests that most Caribbean coral reefs will erode by the year 2100 as sea-level rise outpaces reef growth and limits potential reef restoration.

Modelling suggests that most Caribbean coral reefs will erode by the year 2100 as sea-level rise outpaces reef growth and limits potential reef restoration

go.nature.com/42229kK

Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...

ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS

Comment period ends September 29th

www.federalregister.gov/documents/20...

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Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record Abstract. Protein folds are structural units defined by the number, type, arrangement, and orientation of their core secondary structural elements. The uni

Happy to share Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record 🧪
It appears as part of a Special Section in @genomebiolevol.bsky.social organized by @cpuentelelievre.bsky.social @proteinmechanic.bsky.social and J. Douglas

doi.org/10.1093/gbe/...

The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space".
Date: September 9
Time: 5pm CET
Register here: tinyurl.com/prose-seminar2

Please share!
🧪 #mevosky

Shout-out to @caro-rocha.bsky.social, @lacholt.bsky.social, @zachary-ardern.bsky.social, @romeritos.bsky.social and @hassanzaman.bsky.social

The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space".
Date: September 9
Time: 5pm CET
Register here: tinyurl.com/prose-seminar2

Please share!
🧪 #mevosky

Puente-Lelievre et al. have systematically reviewed how protein structures can be used to trace evolutionary histories. This rapidly advancing field has not yet caught up with the burgeoning databases of high quality protein structure predictions provided by AlphaFold and other tools.

In a new GBE Review, @cpuentelelievre.bsky.social @proteinmechanic.bsky.social & J. Douglas give an overview on protein structural phylogenetics, how to obtain evolutionary insights from structural data, and key applications and future directions.

🔗 doi.org/10.1093/gbe/evaf139

#genome #evolution

EDICa logo, funded by UKRI and British Academy. SURVEY. Bullying & sexual harassment in the UK's research & innovation sector. Have you witnessed bullying or sexual harassment? Have you experienced bullying or sexual harassment? Anyone employed in UK's R&I sector (including postgrad research students). All job types - techs, innovators, researchers, research leaders, R&I managers, administrators, PhD students. All sectors - industry, academia, charity, government. 10-20 minutes to complete. URL and QR code.

Help us gauge the state of the UK's research & innovation sector in terms of preventing and handling bullying & harassment. Please share our survey of anyone who has witnessed or experienced it at work.

go.hw.ac.uk/EDICa/Bullyi...

Thrilled to see this out! Thank you for the shout out @chercheurjuteux.com!

[Resources]

#AlphaFold protein and PPI prediction databases

1️⃣ Predictomes (genome maintenance & H2A/H2b) predictomes.org

2️⃣ Flypredictome www.flyrnai.org/tools/fly_pr...

3️⃣ Human interactome prodata.swmed.edu/humanPPI

4️⃣ BFVD (viral proteins) bfvd.steineggerlab.workers.dev

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Global inhibition of deadenylation stabilizes the transcriptome in mitotic cells In the presence of cell division errors, mammalian cells can pause in mitosis for tens of hours with little to no transcription, while still requiring continued translation for viability. These unique...

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?

www.biorxiv.org/content/10.1...

Members of EU Rosetta Con 2024

Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉

Come join us for three days of protein design fun! (October 20-22, 2025)

Direct registration link: pretix.eu/SBD/RCon2025/
Website: europeanrosettacon.org

We are looking forward to seeing you!

Please share this far and wide:)

¿Te interesaría unirte a nuestro laboratorio como Postdoctoral Fellow?
¿Está interesado en investigar y contribuir a la comprensión del papel de los anaerobios en la salud humana?

Revisa la convocatoria Pew Latin American Fellows

¡Contáctame si cumples con los requisitos!
#Archaea #MicroSky

📖 SMBE journals on Bluesky

Interested in learning the latest advances in evolutionary biology, genomics, and molecular biology? Follow the SMBE sister journals MBE and GBE here on Bluesky and get updates on new articles coming out.

MBE: @molbioevol.bsky.social
GBE: @genomebiolevol.bsky.social

Join us for the next ProSE Seminar!
We are excited to welcome Sophie Heiding for a talk on "Computational Insights into Protein Adaptation Across Environmental Gradients"
Date: June 10
Time: 4PM CET
Register here: tinyurl.com/prose-seminar2
Please share!
🧪 #MEvoSky

Join us for the next ProSE Seminar!
We are excited to welcome Sophie Heiding for a talk on "Computational Insights into Protein Adaptation Across Environmental Gradients"
Date: June 10
Time: 4PM CET
Register here: tinyurl.com/prose-seminar2
Please share!
🧪 #MEvoSky

Reminder that SSE members in Brazil, Colombia, Mexico, India, and 152 low-income countries around the world can still get FREE registration for the virtual Evolution meeting! Please share with your colleagues: www.evolutionsociety.org/index.php?mo...

Happy International Museum Day!

Museums are essential repositories of specimens and information for biodiversity research. GBE has published much research in genomics and evolution that benefited from this crucial function of museums.

See below ⬇️ and continue supporting museum research

#IMD2025

A snapshot of the HLp tetramer (purple) wrapping ~60 bp of DNA (green).

Excited to share our new preprint on HLp—a bacterial histone from Leptospira perolatii that forms stable tetramers and wraps ~60 bp of DNA: "DNA Wrapping by a Tetrameric Bacterial Histone" www.biorxiv.org/content/10.1...

@mpi-bio-fml.bsky.social

We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!

Design of overlapping genes using deep generative models of protein sequences In nature, viruses frequently evolve overlapping genes (OLG) in alternate reading frames of the same nucleotide sequence despite the drastically reduced protein sequence space resulting from the shari...

Very interesting new study from authors including Nobel Prize winner David Baker.

I'm glad that it cites one of my related papers 😀

I've faced plenty of skepticism from editors & others about the importance of this line of research, perhaps this will shift ...
www.biorxiv.org/content/10.1...

We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!