Claudia Alvarez Carreño's Avatar

Claudia Alvarez Carreño

@claudiaalcar.bsky.social

Protein structure evolution | Royal Society Newton International Fellow at UCL | she/her

813 Followers  |  469 Following  |  25 Posts  |  Joined: 02.10.2023  |  1.8831

Latest posts by claudiaalcar.bsky.social on Bluesky

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The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU):

Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t”
Date: October 14th, 5 pm CET
Registration link: tinyurl.com/prose-seminar2

06.10.2025 07:22 — 👍 3    🔁 1    💬 0    📌 0
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Caribbean coral reefs are threatened by rising seas Modelling suggests that most Caribbean coral reefs will erode by the year 2100 as sea-level rise outpaces reef growth and limits potential reef restoration.

Modelling suggests that most Caribbean coral reefs will erode by the year 2100 as sea-level rise outpaces reef growth and limits potential reef restoration

go.nature.com/42229kK

22.09.2025 08:08 — 👍 30    🔁 11    💬 0    📌 1
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Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...

ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS

Comment period ends September 29th

www.federalregister.gov/documents/20...

1/2

20.09.2025 10:38 — 👍 42    🔁 65    💬 5    📌 3
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Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record Abstract. Protein folds are structural units defined by the number, type, arrangement, and orientation of their core secondary structural elements. The uni

Happy to share Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record 🧪
It appears as part of a Special Section in @genomebiolevol.bsky.social organized by @cpuentelelievre.bsky.social @proteinmechanic.bsky.social and J. Douglas

doi.org/10.1093/gbe/...

15.09.2025 07:52 — 👍 20    🔁 4    💬 0    📌 1
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The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space".
Date: September 9
Time: 5pm CET
Register here: tinyurl.com/prose-seminar2

Please share!
🧪 #mevosky

02.09.2025 13:09 — 👍 9    🔁 6    💬 2    📌 1

Shout-out to @caro-rocha.bsky.social, @lacholt.bsky.social, @zachary-ardern.bsky.social, @romeritos.bsky.social and @hassanzaman.bsky.social

02.09.2025 13:09 — 👍 2    🔁 0    💬 0    📌 0
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The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space".
Date: September 9
Time: 5pm CET
Register here: tinyurl.com/prose-seminar2

Please share!
🧪 #mevosky

02.09.2025 13:09 — 👍 9    🔁 6    💬 2    📌 1
Puente-Lelievre et al. have systematically reviewed how protein structures can be used to trace evolutionary histories. This rapidly advancing field has not yet caught up with the burgeoning databases of high quality protein structure predictions provided by AlphaFold and other tools.

Puente-Lelievre et al. have systematically reviewed how protein structures can be used to trace evolutionary histories. This rapidly advancing field has not yet caught up with the burgeoning databases of high quality protein structure predictions provided by AlphaFold and other tools.

In a new GBE Review, @cpuentelelievre.bsky.social @proteinmechanic.bsky.social & J. Douglas give an overview on protein structural phylogenetics, how to obtain evolutionary insights from structural data, and key applications and future directions.

🔗 doi.org/10.1093/gbe/evaf139

#genome #evolution

26.08.2025 16:30 — 👍 14    🔁 8    💬 0    📌 0
EDICa logo, funded by UKRI and British Academy. SURVEY. Bullying & sexual harassment in the UK's research & innovation sector. Have you witnessed bullying or sexual harassment? Have you experienced bullying or sexual harassment? Anyone employed in UK's R&I sector (including postgrad research students). All job types - techs, innovators, researchers, research leaders, R&I managers, administrators, PhD students. All sectors - industry, academia, charity, government. 10-20 minutes to complete. URL and QR code.

EDICa logo, funded by UKRI and British Academy. SURVEY. Bullying & sexual harassment in the UK's research & innovation sector. Have you witnessed bullying or sexual harassment? Have you experienced bullying or sexual harassment? Anyone employed in UK's R&I sector (including postgrad research students). All job types - techs, innovators, researchers, research leaders, R&I managers, administrators, PhD students. All sectors - industry, academia, charity, government. 10-20 minutes to complete. URL and QR code.

Help us gauge the state of the UK's research & innovation sector in terms of preventing and handling bullying & harassment. Please share our survey of anyone who has witnessed or experienced it at work.

go.hw.ac.uk/EDICa/Bullyi...

25.08.2025 11:55 — 👍 3    🔁 9    💬 0    📌 0

Thrilled to see this out! Thank you for the shout out @chercheurjuteux.com!

21.08.2025 19:48 — 👍 7    🔁 2    💬 1    📌 0

[Resources]

#AlphaFold protein and PPI prediction databases

1️⃣ Predictomes (genome maintenance & H2A/H2b) predictomes.org

2️⃣ Flypredictome www.flyrnai.org/tools/fly_pr...

3️⃣ Human interactome prodata.swmed.edu/humanPPI

4️⃣ BFVD (viral proteins) bfvd.steineggerlab.workers.dev

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30.07.2025 11:28 — 👍 26    🔁 9    💬 1    📌 1
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Global inhibition of deadenylation stabilizes the transcriptome in mitotic cells In the presence of cell division errors, mammalian cells can pause in mitosis for tens of hours with little to no transcription, while still requiring continued translation for viability. These unique...

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?

www.biorxiv.org/content/10.1...

23.07.2025 10:57 — 👍 144    🔁 43    💬 6    📌 3
Members of EU Rosetta Con 2024

Members of EU Rosetta Con 2024

Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉

Come join us for three days of protein design fun! (October 20-22, 2025)

Direct registration link: pretix.eu/SBD/RCon2025/
Website: europeanrosettacon.org

We are looking forward to seeing you!

Please share this far and wide:)

26.06.2025 16:29 — 👍 9    🔁 4    💬 0    📌 3
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¿Te interesaría unirte a nuestro laboratorio como Postdoctoral Fellow?
¿Está interesado en investigar y contribuir a la comprensión del papel de los anaerobios en la salud humana?

Revisa la convocatoria Pew Latin American Fellows

¡Contáctame si cumples con los requisitos!
#Archaea #MicroSky

07.06.2025 15:08 — 👍 6    🔁 10    💬 2    📌 0
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📖 SMBE journals on Bluesky

Interested in learning the latest advances in evolutionary biology, genomics, and molecular biology? Follow the SMBE sister journals MBE and GBE here on Bluesky and get updates on new articles coming out.

MBE: @molbioevol.bsky.social
GBE: @genomebiolevol.bsky.social

18.04.2025 07:32 — 👍 10    🔁 8    💬 0    📌 1
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Join us for the next ProSE Seminar!
We are excited to welcome Sophie Heiding for a talk on "Computational Insights into Protein Adaptation Across Environmental Gradients"
Date: June 10
Time: 4PM CET
Register here: tinyurl.com/prose-seminar2
Please share!
🧪 #MEvoSky

29.05.2025 15:16 — 👍 12    🔁 6    💬 0    📌 1
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Join us for the next ProSE Seminar!
We are excited to welcome Sophie Heiding for a talk on "Computational Insights into Protein Adaptation Across Environmental Gradients"
Date: June 10
Time: 4PM CET
Register here: tinyurl.com/prose-seminar2
Please share!
🧪 #MEvoSky

29.05.2025 15:16 — 👍 12    🔁 6    💬 0    📌 1
Membership Site description

Reminder that SSE members in Brazil, Colombia, Mexico, India, and 152 low-income countries around the world can still get FREE registration for the virtual Evolution meeting! Please share with your colleagues: www.evolutionsociety.org/index.php?mo...

24.05.2025 01:02 — 👍 49    🔁 61    💬 0    📌 1

Happy International Museum Day!

Museums are essential repositories of specimens and information for biodiversity research. GBE has published much research in genomics and evolution that benefited from this crucial function of museums.

See below ⬇️ and continue supporting museum research

#IMD2025

18.05.2025 12:35 — 👍 8    🔁 2    💬 1    📌 0
A snapshot of the HLp tetramer (purple) wrapping ~60 bp of DNA (green).

A snapshot of the HLp tetramer (purple) wrapping ~60 bp of DNA (green).

Excited to share our new preprint on HLp—a bacterial histone from Leptospira perolatii that forms stable tetramers and wraps ~60 bp of DNA: "DNA Wrapping by a Tetrameric Bacterial Histone" www.biorxiv.org/content/10.1...

@mpi-bio-fml.bsky.social

12.05.2025 09:16 — 👍 87    🔁 37    💬 4    📌 3
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We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!

01.05.2025 07:32 — 👍 34    🔁 18    💬 0    📌 1
Preview
Design of overlapping genes using deep generative models of protein sequences In nature, viruses frequently evolve overlapping genes (OLG) in alternate reading frames of the same nucleotide sequence despite the drastically reduced protein sequence space resulting from the shari...

Very interesting new study from authors including Nobel Prize winner David Baker.

I'm glad that it cites one of my related papers 😀

I've faced plenty of skepticism from editors & others about the importance of this line of research, perhaps this will shift ...
www.biorxiv.org/content/10.1...

10.05.2025 10:19 — 👍 21    🔁 7    💬 0    📌 1
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We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!

01.05.2025 07:32 — 👍 34    🔁 18    💬 0    📌 1
Preview
Cyclists who kill pedestrians could be jailed for life under new law in England and Wales Reckless cycling is currently prosecuted under legislation from the 1860s, with a maximum two-year jail sentence

Labour continues the stupid culture war politics of the previous govt. 😡 Cyclists killing pedestrians is super rare. There are so many more useful things the govt could spend their time on legislating, e.g making streets safer for cyclists.

www.theguardian.com/news/2025/ap...

25.04.2025 06:59 — 👍 7    🔁 1    💬 1    📌 0
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Dates are now confirmed for the 2025 SMBE Satellite Meeting in Chile: Molecular Mechanisms of Adaptation and Experimental Evolution. Join us in Puerto Varas for the latest advances in evolutionary biology.

Check more details: smbechile2025.cl

📅: 6 – 8 th October 2025
📝 Deadline: July 31

15.04.2025 07:28 — 👍 12    🔁 7    💬 0    📌 0
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Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

Here we unexpectedly find that the ribosomal protein S20/L26—identified at the dawn of ribosome research but later deemed a biochemical artifact—is indeed a genuine component of the large ribosomal subunit. More on this ribosome content variation is here: www.nature.com/articles/s41...

20.03.2025 22:05 — 👍 45    🔁 23    💬 1    📌 2
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💻Hello world! We are 3D-SIG: Structural Bioinformatics and Computational Biophysics, track of the International Society for Computational Biology (ISCB) @iscb.bsky.social 🙌

10.04.2025 19:21 — 👍 9    🔁 4    💬 0    📌 1

The session has ended! We’ll share recordings of all the talks as soon as we’ve finalized the best way to do so. Stay tuned!

08.04.2025 15:09 — 👍 1    🔁 0    💬 0    📌 0

Tomorrow’s ProSE Seminar features Dr. Devlina Chakravarty (@devlinac.bsky.social) presenting “Mutations Switch Folds in Proteins”.
Don't miss out!
April 8, 3PM GMT
Registration link: tinyurl.com/prose-seminar3
🧪 #MEvoSky

07.04.2025 18:31 — 👍 14    🔁 2    💬 1    📌 0
A view inside the British Library, looking at people working in the main foyer space.

A view inside the British Library, looking at people working in the main foyer space.

Do you have experience working with AI?

We’re seeking proposals for presentations and workshops at Fantastic Futures 2025: AI Everywhere, All at Once, this 3-5 December.

Join global experts exploring AI & ML in GLAM, Digital Humanities, and beyond. Submit by 18 May: bit.ly/BLConferenceAI

03.04.2025 15:22 — 👍 29    🔁 15    💬 4    📌 1

@claudiaalcar is following 19 prominent accounts