Grayson Rodriguez, PhD

Redirecting immune signaling with cytokine adaptors Nature Communications - Cytokines are immune signaling molecules that are frequently dysregulated in disease. Here, the authors create engineered cytokine ‘adaptors,’ molecular switches...

Excited to share this work from the Garcia Lab out today in @naturecomms.bsky.social! We engineer "cytokine adaptors", molecular immune switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS

12.03.2025 01:35 — 👍 6    🔁 3    💬 1    📌 0

Parker Institute Awards $525,000 to Advance Diverse Talent in Cancer Research - Parker Institute for Cancer Immunotherapy Donor-powered initiative fuels next generation of scientific innovators, expands equity in cancer research  The Parker Institute for Cancer Immunotherapy (PICI), a collaborative consortium of the worl...

I am honored to be named a RISE Scholar by the Parker Institute for Cancer Immunotherapy, joining a community of incredible and ambitious researchers transforming cancer immunotherapy! www.parkerici.org/the-latest/p...

20.11.2024 17:17 — 👍 4    🔁 1    💬 0    📌 0

Promiscuous Janus kinase binding to cytokine receptors modulates signaling efficiencies and contributes to cytokine pleiotropy Competition among JAKs for receptor binding may underlie cell type–specific differences in cytokine signaling.

Competition among JAKs for receptor binding may underlie cell type–specific differences in cytokine signaling
www.science.org/doi/10.1126/...

19.11.2024 19:19 — 👍 4    🔁 2    💬 0    📌 0

Last month, I successfully defended my PhD in Immunology at Stanford! I am beyond grateful to my family, friends, colleagues, Stanford Immunology, and advisor, Chris Garcia, for their support in reaching this milestone.

17.11.2024 21:39 — 👍 5    🔁 0    💬 1    📌 0