Julian Naderi

Ab-trapping - a peripheral staining artifact in antibody-based microscopy and genomics Antibodies (Ab) are essential for detecting specific epitopes in microscopy and genomics, but can produce artifacts leading to erroneous interpretations. Here, we characterize a novel artifact, Ab-tra...

🚨 Preprint alert 🚨
Excited to share our work on "Ab-trapping," an antibody artifact causing misleading peripheral ("rim") staining in imaging & genomics (IF, CUT&Tag, CUT&RUN). Antibodies fail to penetrate structures, accumulating at the periphery. A 🧵👇
doi.org/10.1101/2025...

Congratulations to Julian Naderi!
As a 2025 Schmidt Science Fellow, the scientist will study a unique protein from Antarctic fishes that prevents freezing in sub-zero temperatures. 🐟 ❄️
See the news here: www.molgen.mpg.de/4870528/Juli...

schmidtsciences.bsky.social @naderij.bsky.social

In the next chapter of this journey, I’ll be working with @schierlab.bsky.social at @biozentrum.unibas.ch , to explore extremophile proteins as a means to improve transplant preservation 🚀🚀🚀

I wouldn’t have reached this point without the incredible support of my peers at my nominating institute @molgen.mpg.de - especially Denes Hnisz - for fostering an environment that encourages creativity and conceptual thinking.

Many thanks to the @schmidtfellows.bsky.social program for selecting me as part of their 2025 cohort! A unique opportunity to apply my training in basic research to address some of the most pressing challenges facing our society today!

Using a newly developed AI model, the research group @schierlab.bsky.social @biozentrum.unibas.ch @unibasel.ch has discovered in #zebrafish that certain sections of #mRNA control the extent of protein synthesis during early embryonic development. ow.ly/4zyU50V7v1c @cellpress.bsky.social

We (schierlab.bsky.social and Seelig lab) are very happy to share that our work has found a home at DevCell cellpress.bsky.social! Free access here: authors.elsevier.com/sd/article/S...
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?