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FOR5159

@for5159.bsky.social

We're a group of enthusiastic scientists aiming to uncover the dynamic principles of prefrontal processing underlying cognitive flexibility!

37 Followers  |  76 Following  |  397 Posts  |  Joined: 14.01.2025  |  1.8945

Latest posts by for5159.bsky.social on Bluesky

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Circuit organization of the rodent medial prefrontal cortex The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous variety of projection neurons a...

This review has turned into my go-to paper for rodent PFC circuit. Useful in the lab and for teaching. Thanks @panastasiades.bsky.social and @carterlab.bsky.social for writing this. www.cell.com/trends/neuro...

18.02.2025 09:21 β€” πŸ‘ 53    πŸ” 16    πŸ’¬ 1    πŸ“Œ 1
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15.03.2025 09:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Conjoint generalized and trajectory-specific coding of task structure by prefrontal neurons Neurons in the medial prefrontal cortex (mPFC) show spatially modulated activities. Muysers etΒ al. show that mPFC neurons fall into distinct functional classes that differ in terms of their spatial tu...

Literature highlight, this week from our consortium! Muyers et al. used an olfaction-guided spatial memory task in mice to show that prefrontal neurons encode both generalized and trajectory-specific aspects of task structure.

www.cell.com/cell-reports...

15.03.2025 09:14 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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10.01.2025 09:48 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Context-dependent decision-making in the primate hippocam... The brain uses different valuation schemes across context...

choice

https://www.nature.com/articles/s41593-024-01839-5

10.01.2025 09:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Literature highlight of the week: Elston and Wallis used a state-dependent choice task in monkeys to show that the hippocampus relays context-based information via theta waves to the orbitofrontal cortex, which informs valuation and...

10.01.2025 09:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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03.01.2025 18:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

elegans.
https://www.cell.com/cell/fulltext/S0092-8674(24)01378-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867424013783%3Fshowall%3Dtrue

03.01.2025 18:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Literature Highlight of the Week:
Almoril-Porras and Calvo et al. demonstrate the necessity of gap junctions in the temperature gradient migration strategies of C....

03.01.2025 18:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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31.12.2024 12:40 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
ScienceDirect

Mugan et al. investigate the effects of environmental complexity on ensemble firing and local field potential in the dmPFC, hippocampus, and dlstriatum of freely moving rats during a foraging task.
https://www.sciencedirect.com/science/article/pii/S0896627324006986?via%3Dihub#bib26

31.12.2024 12:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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20.12.2024 10:19 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Qian et al. explore the dynamic interplay between relevant information and distractor representations in the lateral prefrontal cortex (LPFC) and prearcuate cortex (PAC) of macaque monkeys.
https://www.jneurosci.org/content/early/2024/12/08/JNEUROSCI.1770-24.2024.long

20.12.2024 10:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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07.12.2024 11:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
The thalamus encodes and updates context representations ... The cortico-striatal-thalamic circuit is involved in upda...

Literature highlight of the week: Chen et al. explore thalamic representation and thalamocortical interactions that contribute to hierarchical cognitive control in humans

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002937

07.12.2024 11:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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01.12.2024 09:33 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Literature highlight of the week: Xu et al. show how robustness and sensitivity coexist in neural networks by analyzing neural dynamics in the monkey prefrontal cortex and using comptational approaches

https://www.pnas.org/doi/epub/10.1073/pnas.240948712

01.12.2024 09:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Congratulations to the authors @toonvdm @GiovanniPezzulo

23.11.2024 08:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A hierarchical active inference model of spatial alternat... How cognitive maps of physical and task space interact wh...



https://www.nature.com/articles/s41467-024-54257-3

23.11.2024 08:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Literature highlight of the week: Van de Maele et al. propose a hierarchical active inference model clarifying how the hippocampal-medial prefrontal cortex circuit solves spatial interaction tasks by bridging physical and task-space maps....

23.11.2024 08:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Congratulations to the authors! @HalassaLab

15.11.2024 09:15 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Prefrontal transthalamic uncertainty processing drives fl... By examining neural responses from tree shrews performing...

change
https://www.nature.com/articles/s41586-024-08180-8

15.11.2024 09:07 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Literature highlight of the week: Lam et al. used a decision task with rule reversals in tree shrews and found that relevant thalamic neurons drive prefrontal reconfiguration following a reversal by attributing errors to an environmental...

15.11.2024 09:07 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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08.11.2024 15:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A cellular basis for mapping behavioural structure - Nature Mice generalize complex task structures by using neu...

tasks

https://www.nature.com/articles/s41586-024-08145-x

08.11.2024 15:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Literature highlight of the week: El-Gaby et al. identify an algorithm that relates medial frontal cortex role in schema formation and sequence memory, by internally organizing mnemonic activity according to an abstract structure shared by different...

08.11.2024 15:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Congratulations to the authors! @adredish

01.11.2024 09:48 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
ScienceDirect

cortex
https://www.sciencedirect.com/science/article/pii/S0896627324006986#sec2

01.11.2024 09:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Literature highlight of the week: Mugan et al. show that complex naturalistic environments modulate decision-making strategies, neural representations, and interactions among the hippocampus, dorsolateral striatum, and dorsomedial prefrontal...

01.11.2024 09:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Congratulations to all authors!

27.10.2024 11:25 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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