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Catherine Dulac

@dulaclab.bsky.social

Identifying the neural basis of innate social behaviors using molecular and genetic tools @Harvard @HHMINEWS

7,440 Followers  |  933 Following  |  139 Posts  |  Joined: 26.07.2023  |  1.8887

Latest posts by dulaclab.bsky.social on Bluesky


A amazing new story by @cate-cholamine.bsky.social led by @forrestdrogers.bsky.social on the environmental modulation of paternal behavior in African striped mice, with a newly discovered molecular player of parental control, Agouti! Terrific study, congrats to all authors!...

20.02.2026 12:48 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0
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Murthy Lab to Host Open House Showcasing the Science of Smell on March 6 - Harvard University - Department of Molecular & Cellular Biology On March 6, the lab of MCB’s Venkatesh Murthy will open its doors to the Harvard community for a special Lab Open House, offering visitors an inside look […]

Murthy Lab to Host Open House Showcasing the Science of Smell on March 6 🧠 πŸ§ͺ🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @luxorboero.bsky.social @neurovenki.bsky.social @rachellegaudet.bsky.social @dulaclab.bsky.social @harvardbrainsci.bsky.social @kempnerinstitute.bsky.social

19.02.2026 23:35 β€” πŸ‘ 16    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Doty Lecture to Feature Chromosome Pioneer Kazuhiro Maeshima - Harvard University - Department of Molecular & Cellular Biology The Department of Molecular and Cellular Biology is pleased to announce this year’s Paul Doty Lecture, featuring renowned chromosome biologist Kazuhiro Maeshima of Japan’s National Institute of Geneti...

Doty Lecture to Feature Chromosome Pioneer Kazuhiro Maeshima #STEM πŸ§ͺ 🧬 #AcademicSky #higherEd #Chromatin
www.mcb.harvard.edu/department/n... @rachellegaudet.bsky.social @harvard.edu @kazu-maeshima.bsky.social

18.02.2026 19:23 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2
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Very sad news. Gail Martin (1944-2026) was a figure in developmental biology. She pioneered the field of ES cells.
A great colleague, a friend and a lovely person.

15.02.2026 08:55 β€” πŸ‘ 121    πŸ” 38    πŸ’¬ 6    πŸ“Œ 3
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Portrait of Dr Carla Shatz, a pioneer who mapped how the brain builds itself. A member of @nationalacademies.org, her work on neural circuits reveals how we become who we are.

More: explorers.com/carla-shatz/

#sciArt #NationalAcademies #Science #Neuroscience @nam.edu @nasonline.org

13.02.2026 14:09 β€” πŸ‘ 50    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
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Poem for a snowy Boston. Winter Psalm by Richard Hoffman. #poetry

08.02.2026 01:21 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Can tell how bad it is from 1st sentence: β€œWhile peer review is an essential part of funding meritorious scientific research, it is also important to consider other factors…”

30.01.2026 20:38 β€” πŸ‘ 18    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Today, I would like to honor the memory of Roger Y. Tsien, born on February 1, 1952. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday
www.nature.com/articles/nme...

30.01.2026 14:52 β€” πŸ‘ 76    πŸ” 17    πŸ’¬ 0    πŸ“Œ 2

New preprint from our group (collaboration with @sueyeonchung.bsky.social) showing that discriminating odor components within a complex mixture is constrained by neural sensitivity rather than background interference - likely due to sparse representations at the front end.

29.01.2026 14:10 β€” πŸ‘ 37    πŸ” 13    πŸ’¬ 1    πŸ“Œ 0
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Vagal blood volume receptors compensate for haemorrhage and posture change - Nature A vagal reflex to blood volume changes in the heart involves PIEZO2 and helps to stabilize blood pressure in an upright posture and after blood loss.

www.nature.com/articles/s41... beautiful work from Stephen Liberles’ lab on neural mechanisms of sensing blood volume.

29.01.2026 00:00 β€” πŸ‘ 26    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Two MCB-Affiliated Postdoctoral Fellows Awarded Harvard Brain Initiative Fellowships - Harvard University - Department of Molecular & Cellular Biology Two postdoctoral researchers affiliated with MCB have been awarded highly competitive Postdoctoral Pioneer Fellowships from the Harvard Brain Initiative (HBI), recognizing innovative projects that spa...

Two MCB-Affiliated Postdoctoral Fellows Awarded Harvard Brain Initiative Fellowships 🧠 πŸ§ͺ🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @sanket-walujkar.bsky.social @rachellegaudet.bsky.social @nbellono.bsky.social @harvardbrainsci.bsky.social @harvard.edu

28.01.2026 21:51 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
Attention-like regulation of theta sweeps in the brain's spatial navigation circuit Spatial attention supports navigation by prioritizing information from selected locations. A candidate neural mechanism is provided by theta-paced sweeps in grid- and place-cell population activity, which sample nearby space in a left-right-alternating pattern coordinated by parasubicular direction signals. During exploration, this alternation promotes uniform spatial coverage, but whether sweeps can be flexibly tuned to locations of particular interest remains unclear. Using large-scale Neuropixels recordings in freely-behaving rats, we show that sweeps and direction signals are rapidly and dynamically modulated: they track moving targets during pursuit, precede orienting responses during immobility, and reverse during backward locomotion β€” without prior spatial learning. Similar modulation occurs during REM sleep. Canonical head-direction signals remain head-aligned. These findings identify sweeps as a flexible, attention-like mechanism for selectively sampling allocentric cognitive maps. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, Synergy Grant 951319 (EIM) The Research Council of Norway, Centre of Neural Computation 223262 (EIM, MBM), Centre for Algorithms in the Cortex 332640 (EIM, MBM), National Infrastructure grant (NORBRAIN, 295721 and 350201) The Kavli Foundation, https://ror.org/00kztt736 Ministry of Science and Education, Norway (EIM, MBM) Faculty of Medicine and Health Sciences; NTNU, Norway (AZV)

The hippocampal map has its own attentional control signal!
Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See πŸ“Ή in post 4/6 and preprint here πŸ‘‰
www.biorxiv.org/content/10.6...
🧡(1/6)

28.01.2026 10:03 β€” πŸ‘ 182    πŸ” 62    πŸ’¬ 4    πŸ“Œ 10

Kids, learn Biology this Summer: an amazing opportunity for middle schoolers!...
πŸ§ͺ🧬🧠🦠🌱🐁πŸͺ°πŸͺ±πŸ§«

21.01.2026 20:55 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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MCB Postdoc Surabhi Sreenivas Awarded ADA Fellowship for Type 2 Diabetes Research - Harvard University - Department of Molecular & Cellular Biology Surabhi Sreenivas, an MCB postdoctoral fellow in the lab of Maxim Prigozhin has been awarded a three-year American Diabetes Association Postdoctoral Fellowship to study how the liver regulates […]

MCB Postdoc Surabhi Sreenivas Awarded ADA Fellowship for Type 2 Diabetes Research 🧠 πŸ§ͺ🧬 πŸ”¬ #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @rachellegaudet.bsky.social @amdiabetesassn.bsky.social @hekstralab.bsky.social @dulaclab.bsky.social @rivaselenarivas.bsky.social

20.01.2026 22:24 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

It is an incredible honour to receive this prize. I thank all members of my lab over the years, and my wonderful colleagues and collaborators, who have joined, inspired and supported me on this exciting journey. ❀️ Biozentrum is a fantastic place to do science!

15.01.2026 19:28 β€” πŸ‘ 49    πŸ” 3    πŸ’¬ 11    πŸ“Œ 0

Congratulations @doetschlab.bsky.social !!!.... so well deserved πŸ‘πŸ₯‚πŸŽ‰

15.01.2026 19:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Ontogeny of the spinal cord dorsal horn The dorsal horn of the mammalian spinal cord is organized into laminae where each layer is populated by different neuron types, has distinctive circuit connections, and plays specialized roles in beha...

Excited to share @rbrianroome.bsky.social β€˜s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org

This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.

www.science.org/doi/10.1126/...

08.01.2026 19:59 β€” πŸ‘ 132    πŸ” 41    πŸ’¬ 10    πŸ“Œ 2

Thrilled to start my lab at the @whiteheadinstitute.bsky.social @mit.edu and to join such a special community of creative and inspiring colleagues. The Sullivan Lab asks (1) how and (2) why infections make us sick, bridging immunology and neuroscience to understand host defense at the organism scale

06.01.2026 14:08 β€” πŸ‘ 88    πŸ” 17    πŸ’¬ 2    πŸ“Œ 3

Ascona meetings on neural circuits are amazing conferences in a beautiful setting in Switzerland spanning all scales from genetics and micro-circuit cracking to high level cognition. Check asconacircuits.org for the 2026 program and register soon, as it typically reaches capacity very quickly 🧠πŸ§ͺ

05.01.2026 12:22 β€” πŸ‘ 21    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Just finished my first book of the year: a sober, courageous, yet emotional, eye-opening and haunting narrative by an Ukrainian writer, father and staunch pacifist who enlisted the day his country was invaded. A must read for anyone concerned by current world affairs...

03.01.2026 18:03 β€” πŸ‘ 13    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

I need one too!...

02.01.2026 01:48 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Way back in 1999, Kenji Doya sketched a big picture theory of the brain:

1️⃣The cerebellum is specialized for supervised learning
2️⃣The basal ganglia are for reinforcement learning
3️⃣The cerebral cortex is for unsupervised learning

How does this hold up in 2026? www.sciencedirect.com/science/arti...

01.01.2026 15:36 β€” πŸ‘ 37    πŸ” 10    πŸ’¬ 3    πŸ“Œ 1
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Smarter Microscopes, Faster Maps: Lichtman Lab’s β€œSmartEM” Brings AI to Connectomics - Harvard University - Department of Molecular & Cellular Biology A new paper in Nature Methods (PDF) from the labs of MCB’s Jeff Lichtman and Aravinthan Samuel, of the department of physics and Center for Brain Science, introduces […]

Smarter Microscopes, Faster Maps: Lichtman Lab’s β€œSmartEM” Brings AI to Connectomics 🧠 πŸ§ͺ🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @yaronmr.bsky.social @harvard.edu @harvardbrainsci.bsky.social @natmethods.nature.com @rachellegaudet.bsky.social @thermofishersci.bsky.social

31.12.2025 19:00 β€” πŸ‘ 16    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Harvard College Senior Fajr Khan Named 2025 Pakistan Rhodes Scholar - Harvard University - Department of Molecular & Cellular Biology Harvard College senior Fajr Khan, a neuroscience concentrator whose work spans maternal mental health, child psychology, and the biological foundations of psychiatric illness, has been selected as a [...

Harvard College Senior Fajr Khan Named 2025 Pakistan Rhodes Scholar #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @naoshigeuchida.bsky.social @rachellegaudet.bsky.social @harvard.edu @ox.ac.uk

22.12.2025 19:00 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

I would say, depends: if you are only marginally expert in that field, decline, as other, more available and equally/more expert reviewers can take over. If you are a close expert, let the editor know of your time constraints and do it if they allow extra time. Holiday season is hell for reviews....

18.12.2025 15:56 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Want to track the dynamics of estrogen in the brain across long periods of time? New paper as part of very fun collab with team UCLA Ed Van Veen and Steph Correa! We use a specialized optical reporter and show that this is possible and actually very easy! www.biorxiv.org/content/10.6...

16.12.2025 20:52 β€” πŸ‘ 44    πŸ” 10    πŸ’¬ 1    πŸ“Œ 0
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Nancy Kleckner Recognized for Pioneering Work in Chromosome Dynamics - Harvard University - Department of Molecular & Cellular Biology Nancy Kleckner, the Herchel Smith Professor of Molecular Biology, has been awarded the 2025 Charles E. Helmstetter Prize Lifetime Achievement Award (PDF) in recognition of her groundbreaking research ...

Nancy Kleckner Recognized for Pioneering Work in Chromosome Dynamics πŸ§ͺ🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @rachellegaudet.bsky.social

15.12.2025 22:02 β€” πŸ‘ 33    πŸ” 9    πŸ’¬ 1    πŸ“Œ 1
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Finally, in the MPOA Gal+ Calcr+ hub of parenting, androgens shift the balance: increasing AR activity suppresses retrieval, while removing AR reduces aggression to pups and boosts care. Together: a hormone-to-cell type-to enhancer-to-behavior blueprint for state- and sex-specific parenting 🧠🧬 6/6

13.12.2025 14:13 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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This maternal trigger doesn’t act aloneβ€”it recruits the core parenting hub (MPOA Gal+ Calcr+ neurons). Activating AvPe Brs3+ Vglut2+ neurons drives Fos expression in this hub, showing how a mother-tuned input can power a shared parenting circuit. 5/6

13.12.2025 14:10 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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And we show this is how it works: oxytocin strongly excites these neurons in maternal brains, and deleting Oxtr or prolactin receptor in AvPe Vglut2+ neurons delays pup retrieval. Hormones aren’t just β€œon/off”—they change what the circuit responds to. 4/6

13.12.2025 14:08 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

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