Peder Larson

Teaching MRI and Book For the last 15(!) years I’ve been teaching an introductory MRI course to graduate students, and I struggled to find a textbook that was both rigorous but also accessible to students with a wide varie...

I've written about my journey to this book and future thoughts here
larsonlab.github.io/Teaching-Pri...

For 15(!) years I’ve been teaching introductory #MRI to grad students, and struggled to find a textbook for a wide variety of backgrounds. I'm happy to share an online textbook I created, fully open source (including code for generating figures and plots shown):
larsonlab.github.io/MRI-educatio...

If you like this demo, you will love the great demos by @pezlarson.bsky.social that can be found here:

larsonlab.github.io/MRI-educatio...

(Complete with python code to generate them!)

Yes definitely will be some improvement! particularly for diffusion MRI the image should be better quality, and also some more precise measurements of cancerous tissue

On 9/16/25, celebrate a date of mathematical beauty Pythagorean Triple Square Day, as one man affectionately calls 9/16/25, is a day like no other this century.

On a positive note - Happy Pythagorean Triple Square Day :) #math #MATH
www.npr.org/2025/09/16/n...

This is a great analysis, especially I like the assessment of different variables on performance in detecting aggressive prostate cancer from MRI

important for ML Researchers to see work like this where real world AUCs ~0.7, showing often fundamental challenges in biomedical problems

MRI technology inspires quantum advancement with 2D materials The same technology behind MRI images of injury or disease also powers nuclear magnetic resonance (NMR) spectroscopy, which is used to analyze biological molecules for research on diseases and therapeutics.

Advances in 2D materials are enabling atomic-scale resolution in NMR spectroscopy, offering new possibilities for quantum sensing, computing, and communications. doi.org/g9zm6v

Dr. Peder Larson (@pezlarson.bsky.social) will host @ucsfci2.bsky.social's Segmentation Tools Seminar!

🗓 Wednesday, September 24

🕒 3:00 - 4:30 p.m.

📍Genentech Hall Auditorium or Zoom

See you there!

Magnet Academy - Magnet Academy Magnet Academy is a free resource on magnetism, electricity and the nature of science brought to you by the National High Magnetic Field Laboratory.

It's back to school time!
Check out our Magnet Academy site for free science learning resources!

The prostate cancer #MRI field is embracing sharing and leveraging datasets across institutions for training AI models. Preprint of this recently accepted federated learning exploration:
arxiv.org/abs/2507.22790

Cover art for ChemMedChem

On the cover! The Chekmenev Lab & coworkers: “Carbon-13 Hyperpolarization of α-Ketocarboxylates with Parahydrogen in Reversible Exchange” in ChemMedChem. @chemistryeurope.bsky.social #wsuchemistry #ChemSky #NMRchat #MRI

🧵A new COPD diagnostic schema that includes chest imaging, respiratory symptoms, and spirometry identified more high-risk individuals and excluded low-risk ones. #ATS2025

ja.ma/4dp9i30

Nice to see my @ucsfimaging.bsky.social colleague highlighted! Prof. Vu has been innovating higher resolution brain #MRI and getting this technology into the hands of VA doctors

Open source #MRI is thriving at #ISMRM2025 - even the standing room was full at educational session today! 🎉

New layer-fMRI paper showing 3D-EPI with variable sampling density at 0.56mm resolution. Acquired at the Feinbergatron scanner.
By Park et al.,
doi.org/10.1002/mrm....

NIH cancels its first and largest study centered on women The Women’s Health Initiative has produced numerous influential findings

Well the NIH has cancelled the Women's Health Initiative, the largest study of women in history

It has been running continuously since 1991 and has provided massive key knowledge about diseases in women

Unreal

www.science.org/content/arti...

Happy to walk anyone through this. Our grants are proposed work. We often budget for things like salaries, student tuition, and equipment and consumables (in my field). We work on tight margins - we're often asked to "trim" or modify budgets because program officers try to spread the money.

conference poster

RT @songihanlab The official flier for the new GRC on Magnetic Resonance and Quantum Information Science, June 14-19, 2026, Southern New Hampshire University, MA. Details TBA over time, looking for support from vendors and institutions www.grc.org/magnetic-res... #NMRevents #NMRchat #NMR 🧲

GitHub - PulmonaryMRI/MoCoLoR: Motion-compensated low-rank reconstruction for simultaneous structural and functional UTE lung MRI doi: 10.1002/mrm.29703 Motion-compensated low-rank reconstruction for simultaneous structural and functional UTE lung MRI doi: 10.1002/mrm.29703 - PulmonaryMRI/MoCoLoR

Both papers reconstruct phase-resolved lung MRI with motion-compensated low rank (MoCoLoR) reconstruction algorithm

Available here:
github.com/PulmonaryMRI...

developed at @ucsfimaging.bsky.social Stanford Radiology
and UC Berkeley EECS

Three‐Dimensional Free‐Breathing Ultrashort Echo Time (UTE) 1H MRI Regional Ventilation: Comparison With Hyperpolarized 129Xe MRI and Pulmonary Function Testing in Healthy Volunteers and People With C... 129Xe and 1H anatomical images were acquired with breath-holding, and Xe VDP was computed. UTE 1H MRI was acquired with 3D radial k-space under free-breathing and reconstructed into respiratory-resol....

analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1...

Uses 3D radial UTE, comparisons focused on HP Xe in healthy volunteers and CF patients

@ucsfimaging.bsky.social @bcch-mri-research.bsky.social

Quantifying spatial and dynamic lung abnormalities with 3D PREFUL FLORET UTE imaging: A feasibility study Purpose Pulmonary MRI faces challenges due to low proton density, rapid transverse magnetization decay, and cardiac and respiratory motion. The fermat-looped orthogonally encoded trajectories (FLORE.....

onlinelibrary.wiley.com/doi/full/10....

uses 3D FLORET trajectory, and ventilation processing from PREFUL (phase-resolved functional lung) method

Compelling examples in CF, LAM, BOS, and Post-HSCT with HP Xe comparisons

@cincykidsrad.bsky.social

Two new papers on lung structure and ventilation #MRI with 3D UTE methods, inc patient results

My impressions
- UTE methods (indirect) not as good as HP Xe (direct, but requires inhaled and hyperpolarized gas)
- sequences maturing, processing is critical
- great potential for lung dz evaluation

👀👇
"In this risk model, the 93 million CT examinations performed in 62 million patients in 2023 were projected to result in approximately 103 000 future cancers."
work from @ucsfimaging.bsky.social

@brukercorporation.bsky.social - could this award be coupled with sequence sharing support to expand impact of work and accelerate research progress?

I think this #MRI award from @brukercorporation.bsky.social is a really nice way to recognize novel preclinical sequence work! Past winners include hot topics of ZTE/UTE, hyperpolarized, CEST, MRF, deuterium

Code for both projects 💾
github.com/tblazey/x_epi
github.com/Xiaoxi-Liu/C...

A vendor‐neutral EPI sequence for hyperpolarized 13C MRI Purpose To develop a flexible, vendor-neutral EPI sequence for hyperpolarized 13C metabolic imaging. Methods An open-source EPI sequence consisting of a metabolite-specific spectral-spatial RF exci.....

This adds to work from WashU on EPI sequences
onlinelibrary.wiley.com/doi/10.1002/...

Open‐source implementation of X‐nuclear sequences using the Pulseq framework Purpose Create vendor-neutral modular sequences for X-nuclear acquisitions and build an X-nuclear–enabled Pulseq interpreter for GE (GE HealthCare, Waukesha, WI) scanners. Methods We designed a mod.....

Pulseq as a vendor neutral and open source #MRI pulse sequence programming tool is growing with #Hyperpolarized field entering this area now with a couple published papers and repositories. Here’s our latest contribution
onlinelibrary.wiley.com/doi/10.1002/...
@ucsfimaging.bsky.social

GitHub - LarsonLab/hyperpolarized-mri-toolbox: The goal of this toolbox is to provide open-source research-level and prototyping software tools for hyperpolarized MRI experiments. It is currently base... The goal of this toolbox is to provide open-source research-level and prototyping software tools for hyperpolarized MRI experiments. It is currently based on MATLAB/Octave code, and includes code f...

Credit to @stikov.bsky.social and MRathon for inspiration and a great experience last ISMRM.

Got some of todays work pushed into github.com/LarsonLab/hy...
Hopefully more to come!

I hosted a mini-hackathon today on #hyperpolarized #MRI software, and very pleasantly surprised with it! Fun discussions, new connections, and I think they made some headway on creating python versions of tools, and building digital metabolism phantoms with anatomy. @ucsfimaging.bsky.social