Clinical and Experimetal Allergy - Prof Shamji and Dr Boyle

Management and Research Progress of Severe Asthma in China Severe asthma (SA) accounts for only 3.4%–8.3% of patients with asthma yet ~25% of China's asthma-related socioeconomic burden. Chinese guidelines, specialist training, and health policies have been ...

China’s severe asthma landscape is changing—novel treatments and research lead better patient care! #SevereAsthma #China

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Validation of the PEN‐FAST Penicillin Allergy Clinical Decision Rule in an Asian Cohort PEN-FAST ≤ 2 shows high NPV, validating it as a reliable screening tool in Asians. Direct drug provocation is safe for low-risk patients identified by PEN-FAST ≤ 2. PEN-FAST shows modest discriminati...

PEN-FAST rule validated for penicillin allergy in Asia—supports safe antibiotic use and better patient care. #PenicillinAllergy #ClinicalTools

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Managing Drug Hypersensitivities: Clinicians' Perceptions on an Optimised Documentation Tool With De‐Labelling Feature Click on the article title to read more.

Drug allergy management gets a boost with a de-labelling tool—streamlining records and patient safety! #DrugAllergy #ClinicalTools

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Type‐2 Biomarkers, Asthma Diagnosis and Lung Function Impairment in the General Population Click on the article title to read more.

Type-2 inflammation markers add precision to asthma diagnosis—optimising care for diverse patients! #Asthma #Biomarkers

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Reassessing the Relationship Between Exhaled Nitric Oxide and Acute Bronchodilation in Asthma Patients Click on the article title to read more.

New findings help clarify how FeNO relates to bronchodilation—refining asthma diagnosis and care. #Asthma #FeNO

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Unsupervised Machine Learning Identifies Asthma Phenotypes in the Population‐Based West Sweden Asthma Study Click on the article title to read more.

Machine learning reveals new asthma phenotypes—driving more personalised care for patients, faster! #Asthma #MachineLearning

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Longitudinal Blood Transcriptome Analysis Reveals Dynamic Gene Expression Patterns in Patients With Allergic Rhinitis Following House Dust Mite Subcutaneous Immunotherapy AR inhibits Th1 immune responses and induces B cell activation. SCIT dynamically modulates blood gene expression gradually normalised. SCIT enhanced type I interferon responses and antiviral pathways...

Long-term gene analysis shows how allergic rhinitis patients change on dust mite immunotherapy—precision insights for better allergy care! #Immunotherapy #GeneExpression

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Intestinal Fibroblasts Orchestrate IL‐4‐Driven Th2 Polarisation in Food Allergy via Paracrine Signalling and Nanotherapeutic Targeting Click on the article title to read more.

Fibroblasts in the gut help fuel food allergy reactions—new nanotherapies could interrupt this process! #FoodAllergy #Immunology

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Adherence to Grass Pollen Allergen Immunotherapy and Allergy Medication Use in Patients With Allergic Rhinitis Click on the article title to read more.

Greater adherence to grass pollen immunotherapy means fewer allergy meds needed—commitment pays off! #AllergicRhinitis #Immunotherapy

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Direct and Indirect Pathways Between Patient, Health System and Socioeconomic Factors and Medication Adherence in Asthma Click on the article title to read more.

Asthma medication adherence is complex—patient, system, and social factors all play a part. Let’s close the gaps! #AsthmaCare #Adherence

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Temporal Trends in the Course and Management of Chronic Urticaria at a European Tertiary Center Click on the article title to read more.

Chronic urticaria management keeps progressing—remission and control rates are improving with better therapies! #Urticaria #AllergyCare

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High Stratum Corneum Hydration May Predict Atopic Dermatitis Development in Moisturised Infants Click on the article title to read more.

High skin hydration in infants could signal future eczema risk—an early clue for better prevention! #AtopicDermatitis #PediatricDermatology

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Allergen‐Specific Human Monoclonal IgG Antibodies for Use in Passive Allergy Immunotherapy The last decades have shown the number of subjects developing allergic rhinitis (AR), allergic asthma (AA), atopic dermatitis (AD), and food allergy rose continuously worldwide. To cure these allergi...

Monoclonal IgG antibodies offer new hope for rapid, targeted passive allergy immunotherapy—could this transform allergy care? #Immunotherapy #AllergyResearch

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Treatment Approach to Chronic Rhinosinusitis Based on Endotype: Difference Between East and West Heterogeneity among CRSwNP patients in Western and Eastern countries leads to differences in management. Type 2 (T2) inflammation accounts for the majority of CRSwNP patients in Western countries, wh...

Endotype-based care for chronic rhinosinusitis shows key regional differences; global teamwork needed for better results. #Rhinosinusitis #Endotype #PrecisionMedicine

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Innovative Approaches to Allergic Disease Characterisation: Comprehensive Antibody Profiling and Non‐Invasive Metabolomics Click on the article title to read more.

Comprehensive antibody profiles + metabolomics = next-level allergy diagnosis. Personalised, non-invasive solutions ahead! #AllergyResearch #PrecisionMedicine

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A Safe and Effective 7 Week Updosing Protocol for Bee and Wasp Venom Immunotherapy Click on the article title to read more.

New 7-week protocol for bee/wasp venom immunotherapy boosts safety and speed for allergy sufferers—quicker protection, fewer visits! #VenomImmunotherapy #Allergy

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The Incidence of Addiction and Its Risk Factors in Chinese Chronic Urticaria Patients Click on the article title to read more.

Study finds links between chronic urticaria and addiction risk—highlighting the need for holistic patient support. #Urticaria #Addiction #PatientCare

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Optimal ImmunoCAP Aspergillus fumigatus‐Specific IgE Threshold for Detecting Allergic Bronchopulmonary Aspergillosis in Adults With Asthma: A Diagnostic Accuracy Study Raising the screening threshold for ImmunoCAP A. fumigatus -specific IgE from 0.35 kUA/L to 0.7 kUA/L in asthma preserves high sensitivity for ABPA while improving specificity, potentially reducing u...

Better IgE test threshold means faster, more accurate ABPA diagnosis for adults with asthma—precision matters! #ABPA #Asthma #ImmunoCAP

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Changes in Atopic Sensitisation From 1 to 5 Years of Age: Longitudinal Data From the MIS BAIR Trial Click on the article title to read more.

MIS BAIR study tracks allergy risk as kids grow—sensitisation changes, and early life exposures matter. #AtopicSensitisation #ChildAllergy #MISBAIR

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Remission and Recurrence of Food Protein–Induced Enterocolitis Syndrome: Insights From Oral Food Challenge Outcomes Click on the article title to read more.

Some kids outgrow FPIES, but recurrences can happen after “passing” food challenges—close medical follow-up remains key. #FPIES #ChildHealth #FoodAllergy

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Lipid mediators linked to NSAID-exacerbated respiratory symptoms may hold clues for new treatments. Biomarkers lead the way! #NERD #RespiratoryDisease #Biomarkers

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Quality of Life in Paediatric Food Allergy: Diverging Influences on Parent and Child Reports in the ROAD Study Click on the article title to read more.

Kids and parents describe food allergy’s impact differently: ROAD Study reveals gaps in quality of life perspectives. Let’s bridge the understanding! #FoodAllergy #QualityOfLife #Parenting

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Don't miss the latest CEA podcast, celebrating August’s Allergy in China issue! 3 expert authors discuss new research on childhood risks, food allergies, and innovative strategies for care—shaping the future of allergy prevention in China. #AllergyInChina

www.podbean.com/ew/pb-junfu-...

Children Allergic to Peanut and/or Tree Nuts Are at Risk of Accidental Allergic Reactions Click on the article title to read more.

Children with peanut or tree nut allergies face ongoing risk of accidental allergic reactions—highlighting the need for strict avoidance and better community awareness. #PeanutAllergy #TreeNutAllergy #ChildHealth #Anaphylaxis

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Mass Spectrometry‐Based Proteomics Analysis of Nasal Fluid Uncovers Differentially Expressed Proteins as Potential Biomarkers of Allergic Asthma Click on the article title to read more.

Mass spectrometry reveals new protein biomarkers in asthma—nasal fluid testing may revolutionize diagnosis! #Asthma #Proteomics #Biomarkers

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Food Allergy Prevention: Is Earlier Complementary Food Introduction Really the Optimal Approach? Click on the article title to read more.

Early allergy food introduction cuts risks, but new research says it’s not one-size-fits-all—family guidance needed! #FoodAllergy #ChildHealth #preventionovercure

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Elevated Maternal Unmetabolized Folic Acid During Pregnancy Increases Offspring Allergy Risk Click on the article title to read more.

High maternal folic acid may mean more childhood allergies—new study highlights the need for careful prenatal supplementation. #FolicAcid #Pregnancy #ChildAllergy

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Mapping the Burden and Risk Factors of Allergic Diseases and Asthma Among Aboriginal and Torres Strait Islander People: A Scoping Review Our study reveals Aboriginal and Torres Strait Islander people have a high allergy burden, with asthma the most prevalent; yet they remain under-represented in research.

Aboriginal and Torres Strait Islander communities face unique allergy and asthma risks—culturally informed care is vital. #Allergy #Asthma #IndigenousHealth

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New Topical and Systemic Treatments for Atopic Dermatitis This review summarises new topical and systemic treatments for atopic dermatitis, their relative effectiveness, and important safety data.

New topical and systemic therapies deliver improved relief for atopic dermatitis—biologics and advanced creams lead the way! #AtopicDermatitis #Eczema #Dermatology

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Food Anaphylaxis: Eight Food Allergens Without Mandatory Labelling Highlighted by the French Allergy‐Vigilance Network Among eight allergenic foods without mandatory labelling involved in ≥ 1% of AVN database food anaphylaxis cases, four (goat's/sheep's milk, buckwheat, peas/lentils, pine nuts) should be considered f...

Eight hidden allergens trigger anaphylaxis but aren’t listed on food labels—urgent call for better labelling in France! #FoodAnaphylaxis #Allergy #FoodSafety

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