Mina Shaigan

🔬 Ever wonder how your immune system ages?
📊 We used single-cell multi-omics (RNA + ATAC) + bulk ATAC on PBMCs to build a cell-by-cell map of aging.
🧠 Find out which genes fade, which chromatin gates clos and why some immune systems age slower.
👉 Poster C-482 #RegSys
#ISMBECCB2025 #Aging #Multiomics

Linking regulatory variants to target genes by integrating single-cell multiome methods and genomic distance - Nature Genetics This study introduces pgBoost, a gradient boosting framework that predicts regulatory single-nucleotide polymorphism–gene links by combining existing linking scores from single-cell multiomics dataset...

Linking regulatory variants to target genes by integrating single-cell multiome methods and genomic distance
www.nature.com/articles/s41...

Great conversations and inspiring vibes at @events.embl.org — felt amazing to share my work and hear from incredible speakers!
#EESAgeing #SingleCell #Aging #ATACseq #RNAseq #Immunology #Multiomics #scRNAseq #scATACseq

🔬 Your immune system doesn’t just weaken with age—it evolves. We mapped how.
📊 We used single-cell multi-omics (RNA + ATAC) + bulk ATAC on PBMCs to build a cell-by-cell map of aging.
👉 Poster 83, EMBO | EMBL Symposium
#SingleCell #Aging #EMBL #Multiomics #scRNAseq #scATACseq

Grunion Dance: By the Light of the Moon photo by Kelly Scofield There has been much interest in the full moon lately because of recent headlines about the ‘super blood wolf moon’ in January (coincident with a lunar eclipse) and the ‘supe…

Grunion Dance: By the Light of the Moon cdfwmarine.wordpress.com/2019/03/11/g...

Goodbye electrons: Future computers may be powered by magnons Scientists, led by Dr. Chumak, create a processor harnessing magnon transport to reduce energy consumption, marking a milestone in computing.

www.earth.com/news/goodbye...

Biological aging may not be driven by what we thought A new study draws a line between random genetic mutations and predictable epigenetic changes used to measure biological aging.

Biological aging may not be driven by what we thought www.livescience.com/health/agein...

Attractor Landscape Analysis Reveals a Reversion Switch in the Transition of Colorectal Tumorigenesis REVERT (REVERse Transition) is presented, a systems framework developed to identify a reversion switch in the transition process of tumorigenesis through comprehensive attractor landscape analysis of...

advanced.onlinelibrary.wiley.com/doi/10.1002/...

Inge Lehmann: Discoverer of the Earth's Inner Core | AMNH Lehmann used seismic signals to expand our knowledge of the Earth's core.

www.amnh.org/learn-teach/....

With new data, researchers attempt to overturn long-held theory on ice ages and climate change Figuring out the mechanisms behind the last abrupt climate shift could help us predict and understand how climate change manifests now.

thebulletin.org/2024/07/with....

Genetic study sheds light on changes that shaped human brain evolution A new Yale study provides a fuller picture of the genetic changes that shaped the evolution of the human brain, and how the process differed from the evolution of chimpanzees.

phys.org/news/2025-02...

Study suggests catalyst for human brain evolution More than a million years ago, large chunks of the human genome were rearranged—a chance event during egg or sperm formation that led to the deletion, duplication, or reversal of sections of DNA. Thos...

phys.org/news/2023-04...

Who Discovered the Cause of Down Syndrome? It took more than 50 years for Marthe Gautier to set the record straight about her discovery of the genetic cause of Down syndrome

www.scientificamerican.com/article/who-...

Google DeepMind Researchers Unlock the Potential of Decoding-Based Regression for Tabular and Density Estimation Tasks Google DeepMind Researchers Unlock the Potential of Decoding-Based Regression for Tabular and Density Estimation Tasks

www.marktechpost.com/2025/02/03/g...

Aaron Klug (1926–2018) - Nature Structural & Molecular Biology Nature Structural & Molecular Biology - Aaron Klug (1926–2018)

www.nature.com/articles/s41...

mayfieldclinic.com/pe-endopitsu...

Cecilia Payne: Discoverer of the Chemical Makeup of Stars | AMNH What are the stars made of? At 25, Cecilia Payne answered this fundamental question in her Ph.D. thesis.

Profile: Cecilia Payne and the Composition of the Stars www.amnh.org/learn-teach/...

AI Is Too Unpredictable to Behave According to Human Goals AI “alignment” is a buzzword, not a feasible safety goal

www.scientificamerican.com/article/ai-i...

Har Gobind Khorana: The chemist who cracked DNA’s code and made the first artificial gene was born into poverty in an Indian village Khorana rose from humble beginnings in India to decipher the genetic code. But his enormous contribution to science has been largely overlooked.

theconversation.com/har-gobind-k...

step1.medbullets.com/endocrine/10...

neurochirurgica.org/m/spip.php?a...

YouTube video by 3Blue1Brown Transformers (how LLMs work) explained visually | DL5

youtu.be/wjZofJX0v4M?...