Mike Hildeband

Decreased KCC2 expression in the human spinal dorsal horn... : PAIN date there is no evidence supporting or opposing this hypothesis in humans. Here, we demonstrate that KCC2 expression is decreased in superficial dorsal horn neurons of organ donors who died with a do...

Our paper showing decreased KCC2 expression in the human spinal cord in people who died with a history of neuropathic pain is now published in PAIN: journals.lww.com/pain/abstrac... Great work from @oliviadavis.bsky.social and the teams of the De Koninck and Hildebrand labs. ❤️ 🇨🇦 collabs!

22.07.2025 23:01 — 👍 34    🔁 8    💬 1    📌 3

Thrilled to celebrate graduation with these amazing honours thesis students from our team. All-stars that are all pursuing next career steps in research and medicine. The future is bright! 😊

18.06.2025 18:42 — 👍 5    🔁 0    💬 0    📌 0

The NIH HEAL Initiative 2025 Annual Report: Research in Action | NIH HEAL Initiative

The last 2 weeks have been a blur, but sadly I'm no longer at the NIH. Working for #painresearch at the NIH was a great honor and the best job of my life. As part of this amazing team, I'm proud to have worked on the HEAL 2025 Annual Report - pls share! heal.nih.gov/about/nih-he...

14.05.2025 20:51 — 👍 28    🔁 8    💬 5    📌 0

Overhead pic capturing the buzz of the poster presentation session.😊

10.04.2025 16:10 — 👍 1    🔁 0    💬 0    📌 0

So proud of these fabulous @carleton.ca students presenting their honours thesis projects! The future is bright for our Neuro department. 😊

10.04.2025 16:01 — 👍 3    🔁 0    💬 1    📌 0

Opinion: The key to winning the trade war is doubling down on research Canada’s productivity has been on a downward slide for decades. Donald Trump’s trade war has brought a renewed urgency to tackling the issue

The key to winning the trade war is doubling down on research, by @richardgold.bsky.social www.theglobeandmail.com/business/com... via @theglobeandmail.com

30.03.2025 19:35 — 👍 57    🔁 25    💬 2    📌 2

Michael Gold, founding president of USASP, explains why industry can’t fill the gap in funding from cuts to NIH in letter to the editor of local paper (Pittsburgh Post Gazette)

23.03.2025 18:16 — 👍 15    🔁 8    💬 0    📌 0

#NAPainSchool patient partner in 2023 Jennifer Daly-Cyr, a dedicated advocate and patient partner at the Chronic Pain Network was interviewed by Emily Mills.

💫Pushing the Boundaries of Patient Engagement in Pain Research: A Chat with Jennifer Daly-Cyr

💻 www.iasp-pain.org/publications...

19.02.2025 16:29 — 👍 4    🔁 1    💬 0    📌 0

Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use Loss of GABAergic and glycinergic inhibitory efficacy in the spinal dorsal horn is associated with neuropathic pain and opioid-induced hyperalgesia in rodent models. Downregulation of the KCC2 chlorid...

Very excited to share our new preprint: "Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use" led by @oliviadavis.bsky.social and Samuel Ferland, a collab between us, Yves De Koninck and Mike Hildebrand labs www.biorxiv.org/content/10.1...

20.01.2025 14:05 — 👍 44    🔁 14    💬 2    📌 3

No, a local Bridgehead, ya hoser! 😜

07.01.2025 03:55 — 👍 2    🔁 0    💬 0    📌 0

How it started/ How it's going. 🥰 Merry Christmas, all!

25.12.2024 00:32 — 👍 8    🔁 0    💬 0    📌 0

This project was driven forward by Justin Bellavance - a very talented honours thesis student. Justin is now at the University of Montreal, doing an MSc in Bioinformatics. 👏

16.12.2024 13:54 — 👍 2    🔁 0    💬 0    📌 0

An Open‐Source Tool for Investigation of Differential RNA Expression Between Spinal Cord Cells of Male and Female Mice Chronic pain is a highly debilitating condition that differs by type, prevalence, and severity between men and women. To uncover the molecular underpinnings of these differences, it is critical to an....

Interested in potential sex differences in gene expression in adult mouse spinal cord neurons? Excitatory versus inhibitory dorsal horn neurons? Check out this online tool and technical report that enables you to dig deeper. 👇😊

onlinelibrary.wiley.com/doi/10.1002/...

16.12.2024 13:42 — 👍 23    🔁 7    💬 4    📌 0

Loving this new Bluesky community. 😊 If you are in Ottawa, join us at Carleton tomorrow at 6 PM to hear of some exciting advancements in pain research, management and support! 👇 No worries if you haven't registered yet. We'll save some refreshments and snacks for you. 😉 ☕️ 🍪

27.11.2024 13:19 — 👍 9    🔁 1    💬 0    📌 0

Congrats Sascha!

23.11.2024 20:08 — 👍 1    🔁 0    💬 0    📌 0