The unique lipopolysaccharide composition of Salmonella Typhimurium ST313 dampens pyroptosis and inflammasome activation and suppresses host cell death https://www.biorxiv.org/content/10.1101/2025.09.29.679141v1
30.09.2025 03:18 β π 2 π 1 π¬ 0 π 0
Link to HHMI preprint mandate hhmicdn.blob.core.windows.net/policies/Imm...
24.09.2025 23:28 β π 37 π 20 π¬ 0 π 2
New preprint in the lab! How the mitochondrial ETC works during infection of human macrophages with #Legionella or #Salmonella? Spoiler: there are some similarities and also pathogen-specific differences. Work led by Francisco Garcia and Paula MartΓnez, with @cbuch.bsky.social at @pasteur.fr
05.09.2025 14:08 β π 13 π 6 π¬ 0 π 0
π 𧬠Insightful dive into in-host bacterial evolution under antimicrobial pressure, a work from @csavin.bsky.social and @pierrelebury.bsky.social in our lab at @pasteur.fr
23.09.2025 06:22 β π 6 π 3 π¬ 0 π 0
Time for some insights into our latest #preprint
Using cryoβelectron tomography, we peeked inside different #Mtuberculosis strains, and a couple of other mycobacteria.π§ Surprise: some species, especially the host-adapted ones, build intracytoplasmic membranes (we call them MIMs)! π¦
22.09.2025 19:25 β π 8 π 6 π¬ 1 π 0
More outstanding maps in this Mercator / 'Correct The Map' explainer by Reuters π
www.reuters.com/graphics/AFR...
18.09.2025 12:45 β π 33 π 9 π¬ 2 π 1
Mycobacterium tuberculosis forms nitrate-induced intracytoplasmic membranes (MIMs) that rewire metabolism & dampen inflammation during infection, uncovering a new layer of bacterial adaptation!
βοΈ @camimille.bsky.social @enningalab.bsky.social @pasteur.fr
π shorturl.at/9kbDM
19.09.2025 07:42 β π 5 π 4 π¬ 0 π 0
Registration & abstract submissions are open for the #Shigella meeting! Travel grants available too! All are welcomed, whether you are active in #Shigella research or interested in the 21st century perspective on this formidable pathogen! π¦ π§« #Microsky
www.shigella2026.conferences-pasteur.org/home
19.09.2025 01:12 β π 5 π 6 π¬ 0 π 0
Come and join us in Paris 2026 to talk all about Shigella!
18.09.2025 12:46 β π 9 π 10 π¬ 0 π 1
After years of hard work and months of growing MTB @camimille.bsky.social submitted her story ! Check this out if you wanna discover new intrabacterial structures and their function ! π¦ π¬β¨
18.09.2025 17:52 β π 5 π 3 π¬ 0 π 0
π¦ Mycobacteria aren't just tough, they're interior designers! π¦ Check out our latest #preprint π¨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity π€«
Thread coming soon!
18.09.2025 16:58 β π 32 π 20 π¬ 0 π 3
New preprint from the lab! Great work led by @camimille.bsky.social #mycobacterium #TB #cryoET
18.09.2025 13:39 β π 6 π 2 π¬ 0 π 0
There are half a million cases of invasive non-Typhoidal Salmonella (iNTS) every year and while you might know S. Typhimurim and Enteritidis, you may not have heard of S. Panama π© π©Έ π§« π Check out our latest in @lancetmicrobe.bsky.social doi.org/10.1016/j.la... and the π§΅ below to find out more 1/n
27.07.2025 08:35 β π 57 π 27 π¬ 2 π 3
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04.09.2025 12:40 β π 4 π 4 π¬ 0 π 0
Anyway, go take a look! There will be some media coverage, I will add to this thread once itβs out!
04.09.2025 11:52 β π 1 π 0 π¬ 0 π 0
Moreover, something we discussed a lot about as it was extremely intriguing at the beginning, it seems that there is a strong level of cellular adaptation when demethylation is slow and gradual vs when itβs fast!
04.09.2025 11:52 β π 1 π 0 π¬ 1 π 0
She worked so incredibly hard for this one and it shows! She showed that DNAme at the centromeres influences CENP-A localisation and centromere function
04.09.2025 11:52 β π 1 π 0 π¬ 1 π 0
Sending you lots of strength, from me and the fur-babies!
01.09.2025 08:24 β π 1 π 0 π¬ 0 π 0
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
28.08.2025 07:03 β π 98 π 43 π¬ 1 π 5
Want 1,000 more steps a day?
Donβt buy a Fitbit.
Move to a walkable city.
A US-wide natural experiment shows people who moved to high-walkability areas added ~1,100 steps/day on average, regardless of age, gender, or BMI. www.nature.com/articles/s41...
17.08.2025 11:48 β π 42 π 6 π¬ 4 π 0
Una vez golpista, siempre golpista βπΌ
13.08.2025 22:00 β π 34 π 31 π¬ 3 π 0
Check out π§ our new preprint π:
www.biorxiv.org/content/10.1...
Congratsπ to @vasilgaisin.bsky.social and Corina Hadjicharalambous, who studied contractile injection systems directly in hot springβ¨οΈ bacterial matsπ¦
#microsky #teamtomo #Chloroflexota
12.08.2025 07:22 β π 61 π 24 π¬ 2 π 2
Postdoc program at the MDC in Berlin, @mdc-berlin.bsky.social : take a look ππ
For this call, collaborative projects between two groups will be funded. Take a look at the call and the groups and drop me an email if interested. Share with colleagues too!
www.mdc-berlin.de/postdocs#t-g...
04.08.2025 10:23 β π 11 π 8 π¬ 0 π 0
π£ I'm recruiting a postdoc researcher to join my team for a project on mosquito-specific viruses and host interactions. Peep the job description & how to apply below. Perfect for soon-to-be or recent PhD graduates in mosquito vector biology π¦ or arbovirology π¦
ποΈ Application deadline 31 August 2025
28.07.2025 09:25 β π 56 π 61 π¬ 1 π 0
An image showing the ARTIC and Pathoplexus logos connected by blue lines, with the text "Hiring: post-doc/software engineer" and "Global open-source pathogen tools" and "Join Swiss TPH, Work on ARTIC2 and Pathoplexus, Basel, Switzerland"
π’New job posting!π’
Are you excited by the idea of building global infrastructure to make pathogen sequencing more accessible, interpretable, and equitable? π§π»βπ»π§¬
My group at @swisstph.ch has an opening working with ARTIC2, @pathoplexus.org, & Loculus - read on!
1/5
25.07.2025 10:44 β π 66 π 68 π¬ 5 π 2
fantastic work!! congrats!! π€©
25.07.2025 14:29 β π 0 π 0 π¬ 0 π 0
π¦ π§ββοΈFrom bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
24.07.2025 18:22 β π 262 π 122 π¬ 9 π 11
Lecturer in Infectious Disease at KCL, Infectious Disease and Antibiotic Resistance fighter, zebrafish model devotee, science ambassador.
PhD student at Cambridge | AMR | genomic surveillance | microbiome
Postdoctoral Researcher / University of Cambridge π©π»βπ¬
Post-doc at @judith-behnsen lab, UIC | PhD @iisermohali | Science Interests: pathogens and their interactions with host
Senior Researcher at
@icrawater.bsky.socialπ§
Focus on #microbiology, #AMR, #OneHealth, #biofilms, #phages, #metagenomics, and #bioinformatics
π¬ Assistant Prof, Pathology βͺ@Duke | Director, Clin Micro Lab
π§« Former Clin Micro Fellow βͺ@Memorial Sloan Kettering
π©π»βπ¬ Former Postdoc @broadinstitute.org
π PhD @The Rockefeller University
Focus: Diagnostics, AMR, Structural Biology
PhD candidate (Blaskovich Lab, IMB @ UQ)
Synthetic chemistry & microbiology (let's takcle biofilms!)
Can be found dancing, surfing, & cycling ππΌππ»π§ͺππ§¬β¬
Working and living on unceded lands
Research Fellow at the University of Melbourne
enteric bacteria, evolutionary dynamics, antimicrobial resistance, genomic epidemiology
Microbiologist, Assistant Professor at Western Michigan University
koestlerlab.com
Post-doc at UCL/London Centre for Nanotechnology (https://www.hoogenboom-lab.com/).
Biophysicist π§ͺ using atomic force microscopy π¬ to map outer membrane biogenesis at the single-protein level in living bacteria π¦
Assistant prof @ UofT, associated scientist @ Helmholtz Institute for RNA-based Infection Research. Pathogen systems biology / informatics / functional genomics. Coastal New Hampshirite. Drink Moxie.
I study infection and inflammation, specifically inflammasomes + host-pathogen interaction at barrier tissues. Epithelial cells are the best. Associate Prof. @ohsummi.bsky.social⬠Opinionated opinions mine. Immigrant. She/her
Group Leader at KCL studying host pathogen interactions
Deputy director of the French NRC for E. coli, Shigella and Salmonella at @pasteur.fr. Interested in all things #AMR and #foodborne_pathogens.
Postdoctoral Researcher based at University of Cambridge | He/Him | Medical Microbiology | Antimicrobial Resistance (AMR) | Genomic Epidemiology | Sexually Transmissible Infections | Bioinformatics | Public Health | Views are my own | Following β endorsing
PhD candidate in the Helaine lab at HMS BBS, studying salmonella, macrophages, and everything in between. Formerly @ Cambridge Pathology and Middlebury MBBC
Microbiologist :)
Studying bacterial pathogenesis, AMR & antimicrobial development.
Research fellow @ Institute for Molecular Bioscience, UQ
Previously Postdoc @Dunn School of Pathology, University of Oxford.
PhD @The Australian National University
Postdoc at the Dunn School (University of Oxford) researching how Salmonella evades the Immune system