Christine Sedore

Make males live more than 400% longer and prevent sexual disfunction late in life?! We're down with it. Our latest preprint: Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life. www.biorxiv.org/content/10.1...

06.11.2025 23:14 — 👍 40    🔁 15    💬 3    📌 4

#worm25 making sure we get our steps in

02.07.2025 14:53 — 👍 9    🔁 0    💬 0    📌 0

NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse po... A core facet of the National Institute on Aging’s mission is to identify pharmacological interventions that can promote human healthy aging and long life. As part of the comprehensive effort toward th...

Big overview of more than a decade of hard work: NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations
link.springer.com/article/10.1...

07.04.2025 18:05 — 👍 9    🔁 5    💬 0    📌 0

Graph showing that the broccoli derivative sulforaphane makes the transcriptome of treated individuals look "younger" than untreated controls.

New preprint. This is a fun one. Eat your broccoli, but not too much! The broccoli derivative sulforaphane extends lifespan by slowing the transcriptional aging clock www.biorxiv.org/content/10.1...

15.05.2025 21:53 — 👍 12    🔁 2    💬 0    📌 2

Go worms! #worm25

30.06.2025 00:57 — 👍 85    🔁 21    💬 0    📌 4