Leo Speidel

Seeking a few Senior Research Scientists, Research Scientists, Postdoctoral Researchers at Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical...

New ad for an independent postdoc in mathematics/statistics/machine learning for Biology in my institute at RIKEN (not my lab), ranging from 3 to 7 years. Our institute is entirely English-run, and a good mix of expertise on maths/physics/stats/bio! www.riken.jp/en/careers/r...

Seeking a few Postdoctoral Researchers at Mathematical Genomics RIKEN ECL Research Unit (25-695)

Postdoc position in my group in Tokyo!
Please get in touch if you are interested.

And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab.

Job Ad: www.riken.jp/en/careers/r...
Lab page: speidellab.github.io

Senior Research Associate in Population Genomics (RA2327) in University of East Anglia | UEA View details and apply for this Senior Research Associate in Population Genomics (RA2327) vacancy in University of East Anglia. Faculty of Science School of Biological Sciences Senior Research A...

A 4-year postdoc position in population genomics is available in my group at the University of East Anglia, to work on a project sequencing a thousand fox genomes across rural and urban environments in the UK.

vacancies.uea.ac.uk/vacancies/15...

Not Just $N_e$ $N_e$-more: New Applications for SMC from Ecology to Phylogenies Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Ma...

Our review of recent Sequentially Markovian Coalescent methods is up on arXiv: arxiv.org/abs/2506.00692 (based on last year's @official-smbe.bsky.social symposium)

🧵1/n ✨🔮✨ Meet (y)our instructors of this year's #HAAMsummerschool 👇 #aDNA #course #humanpopgen

I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.

Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.

Ancient Borrelia genomes document the evolutionary history of louse-borne relapsing fever Several bacterial pathogens have transitioned from tick-borne to louse-borne transmission, which often involves genome reduction and increasing virulence. However, the timing of such transitions remai...

Our @ucl.ac.uk @crick.ac.uk work, out this week in @science.org, traces a genetic time series of bacterial infections to reveal when and how Borrelia recurrentis jumped from ticks to humans—via our body lice.

www.science.org/doi/10.1126/...

Our new paper is out in @science.org! By exploring the rich genetic diversity of Brazil, we show how fine-scale genomic analyses reveal that this diversity, rooted in Indigenous ancestry and centuries of complex demographic history, plays a key role in population health.

A structured coalescent model reveals deep ancestral structure shared by all modern humans - Nature Genetics The cobraa model extends the pairwise sequentially Markovian coalescent to identify structured population history by examination of the model transition matrix. Applied to human polymorphism data, cob...

Our paper on ancient human population structure is now published. We find that the ancestors of modern humans lived in multiple populations during the period when Homo sapiens evolved in Africa. www.nature.com/articles/s41...

We are excited to announce a new faculty position here in Cambridge, for researchers in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Come and join us! Happy to answer questions about research, teaching and working here. www.jobs.cam.ac.uk/job/50414/

Cephalopod sex determination and its ancient evolutionary origin Octopuses, squids, and cuttlefishes—the coleoid cephalopods—are a remarkable branch in the tree of life whose members exhibit a repertoire of sophisti…

Octo-squid-nautiloid sex chromosomes!

www.sciencedirect.com/science/arti...

Ancient genomics and the origin, dispersal, and development of domestic sheep The origins and prehistory of domestic sheep (Ovis aries) are incompletely understood; to address this, we generated data from 118 ancient genomes spanning 12,000 years sampled from across Eurasia. Ge...

Thread and open access version to come-
Ancient genomics and the origin, dispersal, and development of domestic sheep | Science search.app/gtSKYHF5HqRa...

#adna

I posted a couple days ago about our new paper on building causal graphs from genetic associations + Perturb-seq.

Here I want to expand on the value of using DIRECTIONAL information contained in LoF burden tests.🧵
[work led by @minetoota.bsky.social ]

bsky.app/profile/jkpr...

📢📢📢 #SMBE2025 Abstract Submission EXTENDED to Saturday, February 15, 2025

We also invite you to register at www.smbe2025.org

@SMBEmeetings

A putative ecocline in Klebsiella pneumoniae Are quantitative traits important for bacteriology? The quantitative trait models used in animal and plant genetics assume that the trait takes continuous values and is influenced by many variants cir...

Excited to share our preprint "A putative ecocline in Klebsiella pneumoniae" and super-interested to get your feedback. Really want to use the hive mind to get to the bottom of this phenomenon ASAP. www.biorxiv.org/content/10.1...

My bluesky debut!

One week to the submission deadline for SMBE 2025, Beijing 20-24 July smbe2025.scimeeting.cn

@anaignatieva.bsky.social and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.