Miguel Soares

Food for thought from:
‪@lferreiramoita.bsky.social‬ in JCI - Biological and clinical implications of a model of surveillance immunity www.jci.org/articles/vie...

Obrigado!

Bilirrubina, pigmento amarelado natural do corpo, pode combater a malária Substância controla doença de várias maneiras; pesquisador espera que, no futuro, seja possível usar descoberta em terapias

At Folha de São Paulo: folha.com/38iy72bz
@gimmfoundation.bsky.social

Could have not said it better!

Beautiful new work from Maz Divangahi lab about the enhanced anti-tumoral activity of β-glucan + BCG trained neutrophils leading to tumor eradication.

#freshoffthepress @cp-immunity.bsky.social

A recent study based on observations in humans and experiments in mice proposes that induction of bilirubin production in response to Plasmodium spp. infection is an evolutionary conserved mechanism against malaria. 🧪 www.science.org/doi/10.1126/...

Rewring lipid metabolism to sustain thermoregulation during sepsis. Don’t let it get cold! A very interesting piece from Miguel Soares lab @elmiguelche.bsky.social @gimmfoundation.bsky.social

The future of heart health: AI, immunity, and personalized prevention

The future of heart health: AI, immunity, and personalized prevention | Science | AAAS www.science.org/content/webi...

Call for our new PhD program is open. Come join one of our labs at Gulbenkian Institute for Molecular Medicine - Lisbon-Oeiras, Portugal. Help us spread the word

A bioenergetic basis for multiorgan dysfunction in sepsis https://www.biorxiv.org/content/10.1101/2025.06.12.659280v1

Check out the paper from our latest collaboration with Miguel Soares's lab:
🦠A metabolite-based resistance mechanism against malaria
Now out in Science: www.science.org/doi/10.1126/...

@gimmfoundation.bsky.social @turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi

Rethinking jaundice A buildup of unconjugated bilirubin may be a protective response to malaria

Rethinking jaundice | Science

@gimmfoundation.bsky.social

A metabolite-based resistance mechanism against malaria Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an adaptive or maladaptive r...

A metabolite-based resistance mechanism against malaria | Science www.science.org/doi/10.1126/...

@gimmfoundation.bsky.social

@gimmfoundation.bsky.social

@gimmfoundation.bsky.social‬

@gimmfoundation.bsky.social

There is a price tag for everything…..

www.sciencedirect.com/science/arti... Evolutionary medicine in action: Sickle hemoglobin fuels tumor progression - ScienceDirect

Male mice can grow female organs — if their mothers lack iron Nature - Hear the biggest stories from the world of science | 04 June 2025

Latest from the Nature Podcast 🔊 Male mice can grow female organs — if their mothers lack iron

https://go.nature.com/3SY8I2V

🚨Great new MSc and PhD positions available @gimmfoundation!

Check out the links or use the QR code.

MSc:
www.medicina.ulisboa...

PhD:
gimm.pt/course/phd-p...

Curious about aging & longevity research? Join us at GIMM Fest (Lisbon, Portugal)

Discover groundbreaking insights & engage with top researchers. It's a celebration of curiosity & a catalyst for change.

🗓️ Sept 4-5: Scientific Sessions + Sept 6: Public Event

👉 gimm.pt/gimm-festival/

25 de Abril sempre! Malária nunca mais! <p>Tal como na malária, também não existe uma vacina contra o fascismo. Apenas a educação, a liberdade, a justiça e a empatia nos podem proteger</p>

expresso.pt/opiniao/2025...

@cleeterichter.bsky.social & Kelsey Voss discuss a study from @elmiguelche.bsky.social that highlights a role for monocyte-derived macrophages in iron homeostasis and its control of systemic energy metabolism

Red blood cells undergo lytic programmed cell death involving NLRP3 Complement exposure induces programmed cell death of red blood cells due to the intracellular activation of miniNLRP3 and caspase-8. Inhibiting NLRP3 signaling reduces cytoskeletal damage and prevents...

Red blood cells undergo lytic programmed cell death involving NLRP3: Cell www.cell.com/cell/fulltex...

Is it still not clear?
Abusing the state to force your ideology on others.

Fascism, Fascism, Fascism. There is no other term for this.

Jay Bhattacharya? 🤡🤡🤡 a useful idiot.

Fascism: Why Understanding the Past is Critical for the Present - Department of French, Hispanic and Italian Studies Dr. Carlo Testa explains why understanding historical Fascism is critical to resisting the many forms of Fascism that are arising today.

Important definitions and concepts to understand that what is happening in many countries is not new.

"Fascism is rising again".

It's been back for several years, out in the open. But these four words may need an explanation and a warning.
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Monocyte control of organismal energy homeostasis Multicellular organisms rely on inter-organ communication networks to maintain vital parameters within a dynamic physiological range. Macrophages are central to this homeostatic control system, sensin...

Today in #preprinthub2 Kelsey Voss + @cleeterichter.bsky.social will present a #preprint from @elmiguelche.bsky.social @gimmfoundation.bsky.social
on how monocytes control organismal energy homeostasis 🕹️🧍‍♀️🌊

www.biorxiv.org/content/10.1...

"The system proposed by NIH cannot accomplish its stated goal of cutting costs while maintaining a high-quality national research system." - Choi et al.

The U.S. National Institutes of Health’s recent decision to impose a 15% cap on facilities and administrative cost reimbursements is misguided and damaging, argue the authors of a new #SciencePolicyForum. scim.ag/423AbVX