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Mark Mandel

@markjmandel.bsky.social

Bacterial geneticist focused on microbe-animal communication. Professor UW-Madison. Messages are my personal views.

2,783 Followers  |  859 Following  |  156 Posts  |  Joined: 01.09.2023  |  2.2653

Latest posts by markjmandel.bsky.social on Bluesky

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We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783

07.10.2025 16:10 β€” πŸ‘ 17    πŸ” 27    πŸ’¬ 0    πŸ“Œ 2
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OIST is seeking up to four tenure-track or tenured faculty in Ecology, Environmental Science, Earth Science, and Oceanography. Application deadline: Oct 15. Please share. Thx!
www.oist.jp/careers/facu...

07.10.2025 10:01 β€” πŸ‘ 44    πŸ” 63    πŸ’¬ 1    πŸ“Œ 1
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The NIH ordered me to stop my β€˜dangerous’ gain-of-function research. It isn’t dangerous at all Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis β€” but the NIH has imposed unfounded stops.

Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com

06.10.2025 12:15 β€” πŸ‘ 40    πŸ” 21    πŸ’¬ 1    πŸ“Œ 5
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UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

05.10.2025 12:03 β€” πŸ‘ 61    πŸ” 69    πŸ’¬ 2    πŸ“Œ 1
Opening session of the MMPC conference with Abby Kroken and Jonathan Allen on stage and a slide displayed.

Opening session of the MMPC conference with Abby Kroken and Jonathan Allen on stage and a slide displayed.

Another great @mmpconference.bsky.social wraps up… πŸ‘ to organizers Jonathan Allen and Abby Kroken! @akroken.bsky.social

05.10.2025 21:24 β€” πŸ‘ 19    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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EPP1 is an ancestral component of the plant Common Symbiosis Pathway The success of plants on land has been enabled by mutualistic intracellular associations with microbes for 450 million years (Delaux and Schornack 2021). Because of their intracellular nature, the est...

www.biorxiv.org/content/10.1...
Great story in collaboration with @pierremarcdelaux.bsky.social and @jeanmichelane.bsky.social groups. EPP1 story continues after many years of collaborations with Pierre-Marc and Jean-Michel!!!

02.10.2025 20:11 β€” πŸ‘ 5    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

We were told this morning that NSF will override our out of office emails with their own generic one, so forget what I said. ☹️

01.10.2025 18:13 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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A murine model of adult gastrointestinal colonization by Group B Streptococcus Group B Streptococcus (Streptococcus agalactiae, GBS) is a leading cause of invasive infections in neonates and adults. The adult gastrointestinal (GI) tract represents an understudied site of asympto...

Excited to see Joie Ling's new preprint out! Adult mouse model shows robust GI colonization by Group B Strep without antibiotics. Capsule emerges as a persistence factor in the adult GI.
www.biorxiv.org/content/10.1...

29.09.2025 15:00 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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zol - our suite for detailed comparative analysis of related gene clusters (co-located genes; e.g. BGCs, operons, etc.) - has new color aesthetics, column ordering, & new stats from the peptides library.

It no longer screams at your eyes in 80s-style neon colors πŸ˜€

github.com/Kalan-Lab/zol

29.09.2025 04:36 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

So great to catch up!! Thank you for visiting.

28.09.2025 04:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Heading back from a great visit to Madison! Thank you so much for hosting me, it was wonderful to meet with everyone

27.09.2025 13:56 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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My department at UTK is hiring! πŸ§ͺ🧫 We are hiring two Assistant Professors, one in Microbial Drivers of Chronic Disease and one in Quantitative Microbe-Plant-Environment Interactions! Come join our growing department of microbiologists. Knoxville is a great place to live!

16.09.2025 13:59 β€” πŸ‘ 7    πŸ” 17    πŸ’¬ 0    πŸ“Œ 0
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NSF Graduate Research Fellowship Program (GRFP)

NSF GRFP solicitation out.
App deadlines now in November.
As others noted, eligibility rules for current graduate students now exclude 2nd year grad students. See the solicitation - they’ve emphasized β€œfirst year” and β€œless than one academic year” in grad program.

www.nsf.gov/funding/oppo...

26.09.2025 16:28 β€” πŸ‘ 4    πŸ” 16    πŸ’¬ 1    πŸ“Œ 1
Flyer for the combine workshop: computational modeling in biology network. Listing speakers and showing details and sponsors.

Flyer for the combine workshop: computational modeling in biology network. Listing speakers and showing details and sponsors.

The Computational Modeling in Biology Network (COMBINE 2025) workshop is being held at UW-Madison October 20-23. Great lineup of speakers and workshop leaders. Early registration through this Sunday. co.mbine.org/author/combi...

26.09.2025 15:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Munyoki et al. demonstrate that gut microbiota extend the female reproductive lifespan by safeguarding the ovarian reserve. Germ-free mice undergo accelerated primordial follicle loss and reduced reproductive capacity that are restored upon post-natal colonization. Microbial SCFAs contribute to protection, and dietary fiber supplementation maintains oocyte quality under obesogenic diets.

Munyoki et al. demonstrate that gut microbiota extend the female reproductive lifespan by safeguarding the ovarian reserve. Germ-free mice undergo accelerated primordial follicle loss and reduced reproductive capacity that are restored upon post-natal colonization. Microbial SCFAs contribute to protection, and dietary fiber supplementation maintains oocyte quality under obesogenic diets.

"The microbiota extends the reproductive lifespan of mice by safeguarding the ovarian reserve" www.cell.com/cell-host-mi...

@cp-cellhostmicrobe.bsky.social
@pittdeptofmed.bsky.social Eldin Jaőarević & colleagues

25.09.2025 20:03 β€” πŸ‘ 22    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

We have a protocols paper out led by fantastic post docs Juan Valencia-Bacca and Maidul Islam. More animal tools for the Kleb research community!!

05.08.2025 21:09 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Faculty Professor Associate - Full-Time | Vaughn Cooper We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...

🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
πŸ”— to all 3 w/info: www.linkedin.com/posts/vaughn...

23.09.2025 22:31 β€” πŸ‘ 93    πŸ” 127    πŸ’¬ 1    πŸ“Œ 6

Congratulations Aathmaja!

24.09.2025 20:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Vibrio2026: The International Meeting on the Biology of Vibrios Fourwaves - Vibrio2026: The International Meeting on the Biology of Vibrios

Delighted to announce that The International Meeting on the Biology of Vibrios will be back next year!

Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!

event.fourwaves.com/vibrio2026/p...

18.09.2025 18:24 β€” πŸ‘ 25    πŸ” 14    πŸ’¬ 0    πŸ“Œ 1
Announcement: Medical Microbiology & Immunology Seminar Series, September 26, 12:00 pm, MSB 1520. "The Evolution of Immunity and Pathogenesis within Environmental Microbial Battlegrounds". Dr. Tera Levin, University of Pittsburgh.

Announcement: Medical Microbiology & Immunology Seminar Series, September 26, 12:00 pm, MSB 1520. "The Evolution of Immunity and Pathogenesis within Environmental Microbial Battlegrounds". Dr. Tera Levin, University of Pittsburgh.

Join us on Friday at noon for a great seminar from Tera Levin @teralevin.bsky.social! @uwmadisonmmi.bsky.social

24.09.2025 17:08 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1

I use Fantastical (for other reasons too... their "calendar sets" are awesome). I don't do this for every doodle poll, but for some I'll use their "Propose Another Time" option to suggest meeting times just to myself and hold those times.

23.09.2025 16:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
he Department of Plant Pathology at the University of California, Davis is seeking applications for a fulltime, tenure-track Assistant Professor position in Mycology, with a focus on plant pathogenic, symbiotic, 
or mycotoxigenic fungi and fungal-like organisms (e.g., oomycetes). We are looking for a highly 
motivated and creative scientist with a strong background in mycology and/or the biology of fungi and 
fungal-like organisms that interact with plants. The successful candidate will be expected to develop a 
world-class, externally funded research program that integrates both fundamental and applied aspects 
of fungal biology within the context of plant pathology. We welcome applicants pursuing a wide range 
of research topics related to plant-associated fungi, including but not limited to mechanisms of fungal 
pathogenesis or symbiosis with plants, population genomics and evolution of fungal plant pathogens, 
plant-associated fungal microbiomes and plant-microbe interactions, and/or one health approaches to 
fungal diseases and antifungal resistance. Applicants working in other relevant research areas involving 
pathogenic, symbiotic, or mycotoxigenic fungi or fungal-like organisms that affect plant health are also 
encouraged to apply. The successful candidate will have significant opportunities for collaboration with 
faculty in plant pathology, microbiology, genomics, and agricultural sciences, and to contribute to 
addressing issues of importance to California’s agricultural and natural ecosystems.
The appointee primary teaching responsibilities will be teaching Introductory Mycology, an upperdivision lab class, and SAS 30, Mushroom, Molds & Society, a general education class for non-majors. 
Additional graduate and undergraduate teaching responsibilities may be assigned based on 
departmental needs and the candidate’s expertise. The department offers modern instructional 
facilities, including a newly renovated teaching laboratory.

he Department of Plant Pathology at the University of California, Davis is seeking applications for a fulltime, tenure-track Assistant Professor position in Mycology, with a focus on plant pathogenic, symbiotic, or mycotoxigenic fungi and fungal-like organisms (e.g., oomycetes). We are looking for a highly motivated and creative scientist with a strong background in mycology and/or the biology of fungi and fungal-like organisms that interact with plants. The successful candidate will be expected to develop a world-class, externally funded research program that integrates both fundamental and applied aspects of fungal biology within the context of plant pathology. We welcome applicants pursuing a wide range of research topics related to plant-associated fungi, including but not limited to mechanisms of fungal pathogenesis or symbiosis with plants, population genomics and evolution of fungal plant pathogens, plant-associated fungal microbiomes and plant-microbe interactions, and/or one health approaches to fungal diseases and antifungal resistance. Applicants working in other relevant research areas involving pathogenic, symbiotic, or mycotoxigenic fungi or fungal-like organisms that affect plant health are also encouraged to apply. The successful candidate will have significant opportunities for collaboration with faculty in plant pathology, microbiology, genomics, and agricultural sciences, and to contribute to addressing issues of importance to California’s agricultural and natural ecosystems. The appointee primary teaching responsibilities will be teaching Introductory Mycology, an upperdivision lab class, and SAS 30, Mushroom, Molds & Society, a general education class for non-majors. Additional graduate and undergraduate teaching responsibilities may be assigned based on departmental needs and the candidate’s expertise. The department offers modern instructional facilities, including a newly renovated teaching laboratory.

Please repost -- The Univ. California Davis dept of Plant Pathology is hiring a Fungal biologist / Mycologist

Applications due Dec 1

Application portal: recruit.ucdavis.edu/JPF07339

Screenshot shows part of the job posting (with alt-text of the same text)

22.09.2025 18:58 β€” πŸ‘ 48    πŸ” 92    πŸ’¬ 2    πŸ“Œ 1

Awesome Dave! I may need some info on this...

20.09.2025 19:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Join us to hear from our first MDTP student-invited speaker of the year, Dr. Selena Sagan, this Friday, September 19th!

Dr. Sagan's research explores how positive-sense RNA viruses usurp host cells, replicate their genomes, and cause disease.

@saganlab.bsky.social #virology #microbiology

17.09.2025 15:33 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Congratulations Ben & all!! bsky.app/profile/benw...

16.09.2025 18:42 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...

Such a delight to share our work on the evolution of a cheese rind fungus in @currentbiology.bsky.social.

This is the fantastic PhD work of @nicolasleonlouw.bsky.social and resulted from amazing collaborations, a wedding proposal(!), an undergrad course, & more!

🧡

www.cell.com/current-biol...

16.09.2025 15:55 β€” πŸ‘ 111    πŸ” 47    πŸ’¬ 2    πŸ“Œ 12

Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.

Ie: it's not us (Samtools team)! Be warned

15.09.2025 08:40 β€” πŸ‘ 141    πŸ” 126    πŸ’¬ 2    πŸ“Œ 4
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Hydrogen sulfide production distinguishes Salmonella from close relatives, but its biological significance remains obscure. This study uncovers the secret: Salmonella uses hydrogen sulfide production as a weapon to outcompete E. coli and gain a foothold in the gut.
www.pnas.org/doi/10.1073/...

13.09.2025 18:32 β€” πŸ‘ 103    πŸ” 30    πŸ’¬ 3    πŸ“Œ 1
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Pioneering approach to bacterial cell biology & national leadership - Lasker Foundation Lucy Shapiro

So proud to have trained with Lucy. She is an exceptional scientist, exceptional person, and exceptional mentor. Huge congrats and so well-deserved. laskerfoundation.org/winners/pion...

11.09.2025 23:42 β€” πŸ‘ 124    πŸ” 17    πŸ’¬ 1    πŸ“Œ 0

Congratulations @gracezhong.bsky.social!

11.09.2025 16:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@markjmandel is following 20 prominent accounts