Atanas G. Atanasov

🔬💥 The gut revolution is happening—one patent at a time.

▶️ Over 8000 innovations in just 20 years are reshaping how we fight dysbiosis, from CRISPR-edited bacteria to AI-designed probiotics.

🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...

🌐 #INPST #Microbiome #Biotech

🥜 Are pistachios really that healthy? Yes—big time! Pistachios improve lipids, glucose & blood pressure—no weight gain!

🔗 inpst.net/is-eating-pi...

🌐 #CardioHealth #NutritionScience #INPST

The long-overlooked insects that could save our crops Hoverflies, often mistaken for bees and wasps, pollinate three quarters of our crops. Now we’re discovering we can train them to be even more efficient

The long-overlooked insects that could save our crops www.newscientist.com/article/2504...

Measles deaths down 88% since 2000, but cases surge Global immunization efforts have led to an 88% drop in measles deaths between 2000 and 2024, according to a new report from the World Health Organization (WHO). Nearly 59 million lives have been saved...

#Medsky🧪 #IDsky #episky #publichealth #pedsky @who.int Measles deaths down 88% since 2000, but cases surge. #Measles has resurged in recent years, even in high-income countries that once eliminated it, because immunization rates have dropped below the 95% threshold

www.who.int/news/item/28...

Pumpkin Seed Proteins: The Potentially Alternative Protein Supplements for Food Applications Pumpkin seed proteins are underutilized plant proteins with a balanced content of essential amino acids and health benefits. Benefit from the functional properties and low-cost character, pumpkin seed proteins exhibit great potential for ...

Pumpkin seed proteins: Properties with activities such as antioxidant, blood pressure-lowering, antidiabetic, antibacterial, and anticancer effects
pmc.ncbi.nlm.nih.gov/articles/PMC...
But higher amounts of L-arginine in pumpkin seeds than in peanuts!
www.clinicalnutritionjournal.com/article/S026...

📌 Just out: A scientific analysis of the #DHPSP2024 networking event reveals how digital platforms like X & LinkedIn catalyze global collaboration in Digital Health and Patient Safety.

📖 doi.org/10.37349/edh...

🌐 #DHPSP #ExplorDHT #HealthInnovation

🍕 Pizza Consumption Favors an Improved Disease Activity in Rheumatoid Arthritis 🩺
pubmed.ncbi.nlm.nih.gov/37571389/

Mode of antiviral action of itraconazole and Ku-63794 in HAdV-infected cells. (1) After binding of HAdV to its entry receptor, (2) receptor-mediated endocytosis is induced, leading to (3) endosomal escape and (4) virus uncoating. The virus is shuttled to the nucleus, where (5) transcription of early virus genes is initiated, followed by (6) viral protein synthesis and (7) viral replication. (8, 9) The switch from early to late viral protein synthesis triggers the (10) assembly of new virions and (11) virus release. During infection, HAdV hijacks and activates the host cell machinery, including the activation of the PI3K/Akt/mammalian target of rapamycin (mTOR) pathway. The mTOR signalling is activated through two viral proteins, E4 ORF1 and E4-ORF4, which activate mTOR signalling directly (via PI3K) or indirectly (via PP2A), thus promoting cell growth, cellular and viral protein synthesis and potentially suppressing cellular antiviral response. Itraconazole interferes at two different stages of HAdV infection. The early antiviral effect of itraconazole is mediated by cholesterol sequestration in endolysosomes that hinders virus uncoating and thereby promotes endolysosomal degradation of HAdV. Additionally, itraconazole inhibits the virus-promoted activation of mTOR through activation of AMPK. AMPK inhibits mTOR signalling, thus affecting viral protein synthesis and survival of HAdV-infected cells (induces autophagy of infected cells to clear virus infection). Ku-63794 interferes with mTOR activation by directly inhibiting mTOR and by inhibiting Akt, a protein upstream of mTOR. Akt inhibition promotes TSC1/2 activation, resulting in Rheb inhibition and inactivation of the mTOR pathway. Both mechanisms contribute to lower virus particle production and decreased infection rates.

#Medsky🧪#IDsky #pharmsky #publichealth @britpharmsoc.bsky.social
The findings contribute to the growing body of evidence that manipulation of host pathways, in particular cellular cholesterol homeostasis & #mTOR signalling axis ➡️ a viable strategy to restrict HAdV (human adenovirus) infection.

What is Ashwagandha? Does it actually help relieve stress? Simple ways to add this herb to daily diet - The Times of India Ashwagandha, a potent adaptogen, significantly reduces stress and anxiety by lowering cortisol levels, as demonstrated in multiple clinical trials. St

Ashwagandha improves sleep quality. Its bioactive compounds, including withanolides, have neuroprotective and anti-inflammatory properties that contribute to overall mental well-being and resilience
timesofindia.indiatimes.com/life-style/f...

Hybrid spin sound waves show potential for tunable 6G filters Researchers at RPTU create hybrid spin sound waves that could lead to adjustable 6G frequency filters and smarter microwave components.

#Researchers achieve hybrid spin sound waves that could support advanced #6G

@amitav63.bsky.social
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@akwyz.com
@kalydeoo.bsky.social
@atanas-g-atanasov.bsky.social
@mariopawlowski.bsky.social
@knutjaegersberg.bsky.social
interestingengineering.com/innovation/h...

Ginger is going high-tech!
From cancer therapy to nanomedicine, innovation is exploding in how we use this ancient root.

🔗 inpst.net/exploring-th...

🌐 #Ginger #CRBIOTECH #INPST

#Medsky🧪 #IDsky #Episky #immunosky #publichealth Vaccination has been a central strategy in the global response to COVID-19, with its effectiveness in preventing severe disease well-established.

Gut Microbiota Imbalance Linked to Rapid Global Rise in IBD Global research finds that gut microbiota dysbiosis strongly correlates with rising inflammatory bowel disease rates worldwide.

Gut Microbiota Imbalance Linked to Rapid Global Rise in IBD
#Gastrosky #gastroenterology
www.emjreviews.com/gastroentero...

🌿 Can plants protect the body during cancer radiotherapy?

▶️ Our new review highlights numerous natural compounds that may shield healthy cells from radiation damage

🔗 50 days' free access link: authors.elsevier.com/a/1mBKWAUp3c...

🌐 #INPST #CancerResearch #Phytotherapy

🏆 Separations Young Investigator Award (2000 CHF; Deadline: 31 December 2025), and other Awards

🔗 inpst.net/awards/

🌐 #INPST #Bioanalysis

People often ask me the same question:

“What’s the single most promising anti-aging measure coming in the next decade?”

If you care about where longevity medicine is truly heading, this one’s worth a look.

🔗https://www.instagram.com/reel/DRni2qQgNTS

Physical Activity Over the Adult Life Course and Risk of Dementia This cohort study uses data from the Framingham Heart Study to evaluate whether higher physical activity levels in early adult life, midlife, or late life are associated with lower risk of all-cause o...

Exercising in your 40s and 50s might do more for your brain than you think. A 40-year study of thousands of adults found that people who stayed active in midlife and later life had up to a 45% lower risk of developing dementia
jamanetwork.com/journals/jam...
www.tomsguide.com/wellness/fit...

#Medsky🧪 #IDsky #virosky #publichealth @jidjournal.bsky.social
A comparative study on the joint effects of #SARSCoV2 viral traits (ACE2 binding, immune escape & cell entry) & socio-demographic context on viral lineage fitness across countries with socioeconomic statuses (S)

🏆 Separations Young Investigator Award (2000 CHF; Deadline: 31 December 2025), and other Awards

🔗 inpst.net/awards/

🌐 #INPST #Bioanalysis

🚀 Graphene biosensors are revolutionizing digital medicine with AI-powered, wearable tech for real-time disease monitoring—cancer, COVID-19, Alzheimer’s & more.

50 days' free access link👉 authors.elsevier.com/a/1lNkAdA7Tp...

🌐 #Graphene #DigitalHealth #Biosensors #DHPSP

Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.

Here's the source article

www.science.org/doi/10.1126/...

Epstein-Barr virus reprograms auto-reactive B cells as antigen-presenting cells in lupus

@atanas-g-atanasov.bsky.social
@govindlab.bsky.social
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@mfamyfuerza.bsky.social
@sukianemone.bsky.social

'The microbiome is a bit like a forest': How bacteria in the vagina can improve health The microbiome in the vagina has received less attention than its cousin in the gut – but a well-balanced vaginal microbiome can help protect overall health.

If a woman is sexually active, vaginal dysbiosis makes her more at risk of contracting sexually transmitted infections (STIs). Women with lower levels of Lactobacillus are more at risk of HIV
www.bbc.com/future/artic...
"In Cape Town in South Africa, the rate of HIV is 20-30% ......"

#Medsky🧪 #IDsky #immunosky #publichealth #LongCOVID pathophysiology is a complex & not fully established process. One prevailing theory is that the formation of fibrin amyloid microclots ( #fibrinaloids), due to #Covid infection, can induce persistent inflammation & capillary blockage .

Tattoo artists are now immunological influencers—without a medical license

Skip the needle, pass the fruit 🍌💉

According to a newly published work, genetically engineered plants like bananas and potatoes may soon deliver vaccines you can eat.

▶️ Cheap, scalable, and storage-free.

🔗 inpst.net/insights-int...

🌐 #Biotech #CRBIOTECH #INPST

Targeting RhoA nuclear mechanoactivity rejuvenates aged hematopoietic stem cells - Nature Aging Mejía-Ramírez, Iáñez Picazo, Walter et al. explore how nuclear biomechanical changes limit the regenerative capacity of aged hematopoietic stem cells and show that targeting RhoA rejuvenates aged hema...

Targeting RhoA nuclear mechanoactivity rejuvenates aged hematopoietic stem cells

www.nature.com/articles/s43...

We’ve wiretapped the gut-brain hotline to decode signals driving disease Scientists have made history with a device that successfully eavesdrops on the neuronal chatter between the brain and the gut, furthering our understanding of its intrinsic interconnectedness – and ho...

We’ve wiretapped the gut-brain hotline to decode signals driving disease
#Neurogastro
newatlas.com/health-wellb...

Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron (Cell 185, 860–871.e1–e4; March 3, 2022)

#Medsky🧪 #virosk #idsky #immunosky #publichealth Structural and functional characterizations of infectivity & immune evasion of #SARSCoV2 Omicron revival
@cellpress.bsky.social

www.cell.com/cell/fulltex...

Astrocytic Sox9 overexpression in Alzheimer’s disease mouse models promotes Aβ plaque phagocytosis and preserves cognitive function - Nature Neuroscience Astrocytes are associated with Alzheimer’s disease pathogenesis. We found that the transcription factor Sox9 functions to enhance astrocytic phagocytosis of Aβ plaques via MEGF10, and this clearance o...

Scientists at Baylor College of Medicine have discovered a natural mechanism in the body that not only stops Alzheimer's damage but reverses it
www.nature.com/articles/s41...
Sox9 protein could reverse Alzheimer's: Breakthrough at Baylor College
www.ad-hoc-news.de/boerse/news/...

Frontiers | Health Associations of Various Fruit Forms: Solid Fruits, Juices, and Smoothies The rising prevalence of noncommunicable diseases (NCDs) highlights the need for refined dietary recommendations that distinguish between forms of fruit cons...

UCLA researcher discovers the healthiest way to eat #fruit

www.frontiersin.org/journals/nut...

Cross-sectional survey associations (N = 443)

Fruit smoothies
— best overall #health
— mental health
— energy levels

Fruit juices
— poorest health
— high cholesterol
— low sleep quality

#science 🧪