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David Michonneau

@dmichonneau.bsky.social

MD, PhD, hematologist @hopitalsaintlouis.bsky.social Professor of hematology @upcite.bsky.social @INSERM @institut-leucemie.bsky.social UMR1342 https://www.institut-leucemie.fr/linstitut-de-la-leucemie-recherche/immunologie-translationnelle/

52 Followers  |  118 Following  |  6 Posts  |  Joined: 17.01.2025  |  1.4189

Latest posts by dmichonneau.bsky.social on Bluesky

Gut microbiota–derived TMAVA is a modulator of acute CNS-GVHD In this study, we report that microbiota depletion exacerbates acute graft-versus-host disease in the central nervous system, driven by microglial activati

doi.org/10.1084/jem....

Great collaboration with the group of Robert Zeiser linking microbiota-derived metabolites and central nervous system GVHD

10.07.2025 08:20 — 👍 1    🔁 1    💬 1    📌 0
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Diet outperforms microbial transplant to drive microbiome recovery in mice - Nature Experiments in mouse models show that proper recovery of the intestinal microbiota following depletion, with or without faecal microbiota transplant therapy, is dependent on syntrophic interactions th...

www.nature.com/articles/s41...

19.06.2025 08:25 — 👍 2    🔁 0    💬 0    📌 0
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Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey Bone Marrow Transplantation - Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey

Great collaboration with Robert Zeiser @institut-leucemie.bsky.social @upcite.bsky.social @ap-hp.bsky.social @insermpresse.bsky.social Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey @springernature.com @BMT journal

rdcu.be/ehWV5

16.04.2025 07:36 — 👍 3    🔁 1    💬 0    📌 0
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Efficacy and safety of belumosudil for treatment of cGVHD: multicenter retrospective analysis of the French cohort of the compassionate use program, on behalf of the French Society of Bone Marrow Transplantation and Cellular Therapy Bone Marrow Transplantation - Efficacy and safety of belumosudil for treatment of cGVHD: multicenter retrospective analysis of the French cohort of the compassionate use program, on behalf of the...

Happy to share our last paper, published with @springernature.com in @BMTjournal, about the French experience with belumosudil in the treatment of steroid-resistant cGvHD. Best ORR 57.4% including 14.7% of CR in patients who previously received at least 2 LOT
rdcu.be/efZg9

01.04.2025 18:20 — 👍 4    🔁 1    💬 0    📌 0
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HLA evolutionary divergence score after donor lymphocyte infusion following allogeneic hematopoietic stem cell transplantation Donor lymphocyte infusion (DLI) prevents acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) relapses following hematopoietic stem cell transplantation. Given the life-threatening toxiciti....

Congratulations to Sophie Le Grand for her very interesting paper in Hemasphere about the role of HLA evolutionary divergence score to predict outcome of prophylactic donor lymphocyte infusion after alloHSCT

doi.org/10.1002/hem3...

14.02.2025 15:14 — 👍 1    🔁 0    💬 0    📌 0
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Systems-level immunomonitoring in children with solid tumors to enable precision medicine In a population-based cohort of 191 children with diverse solid tumors, systems-level analyses unravel immune variation with age and tumor type and provide a reference for future precision immunothera...

Systems-level immunomonitoring in children with solid tumors to enable precision medicine: Cell www.cell.com/cell/fulltex...

20.01.2025 19:03 — 👍 5    🔁 1    💬 0    📌 2

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