CBM CNRS UPR4301

Recommandations from "Stop treating code like an afterthought: record, share and value it"
media.nature.com/original/mag...

Antimicrobial peptides | Canal U How can antimicrobial peptides become an alternative to antibiotics ?

And our last video on antimicrobial peptides in English is now out:
www.canal-u.tv/chaines/cbm/... thanks to @agencerecherche.bsky.social

Antimicrobial peptides | Canal U How can antimicrobial peptides become an alternative to antibiotics ?

And our last video on antimicrobial peptides in English is now out:
www.canal-u.tv/chaines/cbm/... thanks to @agencerecherche.bsky.social

How Scientists Turn Massive Molecular Simulations into Clear, Useful Pictures | Marc Baaden Ever wondered how scientists make sense of the billions of atoms and mountains of data churned out by molecular simulations? Our latest review in Frontiers in Bioinformatics dives into the art and sci...

Scientists are turning massive MD data into clear, actionable visuals, from classic 3D to VR—bridging complexity and decision-making. Read more → Frontiers review ↗ #moleculardynamics #visualization 🔬 What do you think?

is.gd/1MefYo

a man sits in a row of red seats in a theater Alt: a man sits in a row of red seats in a theater

@canal-u.bsky.social est vital.
Le CBM a même une chaîne sur www.canal-u.tv/chaines/cbm

Besoin d’une source fiable pour vos #recherches ?
Canal-U, c’est +50 000 vidéos & podcasts en accès libre produits par +400 universités, instituts & musées, dans +60 disciplines.
👉 Découvrez www.canal-u.tv !
@enseignementsup-recherche.gouv.fr @fondationmsh.bsky.social
#CanalU #ESR #sciences

A part of our team at the recent EMBO SUMO conference in La Grande Motte/Montpellier

Image de fossiles avec comme titre "Comment reconnaître les premières traces de vie sur Terre ?"

Quelles sont les 1ères traces de vie sur Terre ?

Une synthèse graphique de Claire Marc, écrite par @cnrs-insu.bsky.social avec la précieuse aide d'Isabelle Daniel @lyongeologie.bsky.social

#vulgarisation #SVT

Thread à dérouler ci-dessous :

1/6

Glioblastome : une découverte scientifique pour mieux comprendre ce cancer agressif A travers l’utilisation de la porphyrine de manganèse (III) tétrakis (acide 4-benzoïque) (MnTBAP), des scientifiques ont identifié la protéine sulfide:q

#ResultatScientifique🔎| Une avancée concernant une nouvelle cible thérapeutique pour le glioblastome, le plus agressif des cancers du cerveau

✍️ Laurent Chatre
📕 Redox Report |

Screening de novo designed protein binders in unpurified lysate using flow induced dispersion analysis Computational protein design can create binders against targets of interest, but identifying binders with sufficient affinity still requires biochemical screening of many designs. In this work, we te....

Experimental verification is increasingly the bottleneck in protein design projects.

In this paper, we develop a new mini-binder screening pipeline based on the microfluidic sizing technique called flow-induced dispersion analysis (FIDA).

doi.org/10.1002/pro....

Sharing once again - and highly recommending - the postdoc positions with Antoni. One of the projects is a collaboration with us and the postdoc will include a sojourn in our lab.

🔬 Postdoc in RNA Biology! Study Rho-dependent transcription termination in Helicobacter pylori using Helicase-SELEX for genome-wide mapping. 2-year position at the intersection of RNA biochemistry & bacterial genetics.
📩 Interested? DM to connect!
#Postdoc #RNABiology #HelicobacterPylori #ScienceJob

Dear colleagues, positions at CNRS (and INRIA) will (in all probability) be announced this winter. By then it will however be too late to properly prepare an application. Recent PhDs, postdocs etc interested in such positions should get right now in contact with teams who would like to recruit them.

The intrinsically disordered regions of organellophagy receptors are interchangeable and control organelle fragmentation, ER-phagy and mitophagy flux - Nature Cell Biology Rudinskiy et al. examine organellophagy receptor features, finding modules of functionally conserved intrinsically disordered regions and defining shared features despite sequence divergence, such as ...

Mitophagy receptors’ IDRs trigger ER fragmentation and ER-phagy when transplanted at the ER membrane.
www.nature.com/articles/s41...

I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.

SUMOylation studies just got a serious upgrade! Fresh out of the lab- our team including our brilliant chemist PostDoc just published a clean, streamlined way to purify SUMO E2 and SUMO RANGAP. Whether one is into structural biology or biochemical wizardry, this toolkit is your new best friend.

Thrilled to restart the Friday seminars with:

- Sept. 12: Aranyadip Gayn
- Sept. 19: Ariel Loubota
- Sept. 26: Hervé Memoni
- Oct. 3: Daniel Duzdevich
- Oct. 10: Guillaume Leseigneur

Production and Purification of SUMO-UBC9 and SUMO-RANGAP1CTD SUMOylation is a post-translational modification catalyzed by a multi-step enzymatic cascade. To gain structural biology insights into the last step of this process, where SUMO is transferred from a S...

We are happy to have contributed a protocol to a book on SUMO methods (work mainly by postdoc El Hadji Cisse and engineer Stéphane Goffinont): link.springer.com/protocol/10....

An open-source version can be found here: hal.science/hal-05232002

Comprehensive mapping of transcription terminator Rho utilization (Rut) sites across the Bacillus subtilis genome Abstract. Recent evidence indicates that the bacterial Rho helicase regulates Bacillus subtilis gene expression in a growth-dependent manner. This regulati

Pleased to share our latest article on Rho-dependent transcription termination in Bacillus subtilis. Great collaboration with Sylvain Durand #IBPC and Elena and Vladimir Bidnenko #INRAE_DPT_MICA
#CNRSchimie

academic.oup.com/nar/article/...

#Communiqué 🗞️ Le CNRS vous invite à découvrir des installations et plateformes expérimentales, habituellement fermées au public, dans ses centres de recherche en France et en Guyane.

👉 www.cnrs.fr/fr/presse/vi...

Today in Chemistry History graphic on Rosalind Franklin and the structure of DNA. Rosalind Franklin was a chemist and X-ray crystallographer whose work was instrumental in the discovery of the structure of DNA. She missed out on a Nobel Prize for her work as they are not awarded posthumously. Photograph 51 is an X-ray diffraction image of DNA taken during Franklin’s research. It was crucial in developing a model of DNA and confirming its double helical structure.

Rosalind Franklin was born #OTD in 1920. She was a chemist and crystallographic who made a key contribution to the discovery of the double helix structure of DNA: www.compoundchem.com/2017/07/25/f...

#ChemSky 🧪

Grateful to have recently hosted my mentor @clausenlab.bsky.social and his family in Orléans. Happy that he could visit @cbm-upr4301.bsky.social , getting to know our lab and team, and that we could share moments of friendship.

Can robots in a swarm act like the cells of an organism? Thanks to Sedeer El-Showk for the new article in @nature.com, which highlights the work of a number of research groups, including our own, on how “Robots demonstrate principles of collective intelligence”. www.nature.com/articles/d41...

Our lab superstar Stephane takes care of our lab in the best way possible. It's an honor to share the lab with him every single day.

The helium crisis – the CNRS is breathing more new life into science For some years now, research laboratories have been suffering from the effects of worldwide inflation on the price of helium, an essential

Research laboratories have been suffering a worldwide inflation on the price of helium, an essential gas in many scientific disciplines. In response, the CNRS is implementing a national supply and management strategy for this rare gas 💨
www.cnrs.fr/en/update/he...

Brillouin microscopy showing strength in non-invasive, live-imaging applications!

Studying fruit fly embryos during gastrulation as cells rapidly change shape @prevedel-lab.bsky.social @gomezjm-devmech.bsky.social @marialep.bsky.social characterised & mapped mechanical changes in 3D. rdcu.be/ev6ZX

L'année 2024 a été riche en découvertes scientifiques, innovations à impact, actualités institutionnelles et grands événements de médiation scientifique. Plongez dans le nouveau rapport d'activité pour découvrir ces moments marquants.

👉 www.cnrs.fr/fr/actualite...

WeTransfer TOS says they can use all your uploaded content for genAI

Bye forever, WeTransfer.

Top stories : le meilleur des actus de la recherche au mois de juin Saviez-vous qu'Einstein a établi les prémices de la mécanique quantique ? Que des chercheurs CNRS ont enquêté sur l'origine des plantes à fleurs ?

Saviez-vous qu'Einstein a établi les prémices de la mécanique quantique ? Que des chercheurs CNRS ont enquêté sur l'origine des plantes à fleurs ?🌼
Découvrez notre sélection des #TopStories du mois de juin.