Gc Rox

Reposting, submit soon!

We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.

Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com

Opening session for the 2025 Midwest Microbial Pathogenesis Conference.Going on with Year 31 of this great get together. @
#mmpcconference

Assistant Professor in Microbiology APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...

🎙️ Job Announcement: Penn State is seeking an ASSISTANT PROFESSOR in MICROBIOLOGY (any subdiscipline) in the Department of Biochemistry and Molecular Biology.

Learn more and Join the Microbiome Jubilee: psu.wd1.myworkdayjobs.com/en-US/PSU_Ac...

Postdoc position (please re-post)
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
h-seifert@northwestern.edu
#MicroSky

STING cyclic dinucleotide sensing originated in bacteria - Nature Structures of prokaryotic homologues of STING permit the reconstruction of the evolutionary trajectory of its incorporation into metazoan innate immunity, and reveal a role for the conserved cGAS–STIN...

Together with @soreklab.bsky.social, our labs discovered that the human cGAS-STING pathway evolved from ancient bacterial proteins in CBASS anti-phage defense

www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...

Postdoctoral Position (Please re-post)
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
h-seifert@northwestern.edu

Our latest efforts to understand Enterococcal wound infection. In long-term collaboration with @gthibault.bsky.social, we discovered how E. faecalis makes extracellular ROS - via EET!⚡️Which in turn dysregulates host UPR to delay wound healing. Led by @aarontan.bsky.social - his videos below are 🤩!

How thoughtful experimental design can empower biologists in the omics era - Nature Communications Here, the authors discuss principles of experimental design that are relevant for all biology research, along with special considerations for projects using -omics approaches, highlighting common expe...

I am really excited to see this article on basic experimental design principles published. Definitely will be mandatory reading for incoming graduate students in my lab. Maggie Wagner who led this article did an amazing job with the illustrations of basic principles www.nature.com/articles/s41...

Happy to see that this fantastic work is in press now! Congrats to the Palmer lab and lead authors @xiaomeiren.bsky.social and @rmasonclark.bsky.social.

Please contact Congress ASAP to raise awareness of this accounting plan.

Cools story about bacterial crosstalk influencing disease relevant traits! 🧪

Northwestern Micro representing at the 2025GRC MAST conference in beautiful Newport. Great science, collegial people but there’s a cloud hanging over us all. ☁️

graphical abstract of the article the extended mobility of plasmids

Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...

Infection and Immunity Journal Homepage Infection and Immunity Journal helps microbiologists, immunologists, epidemiologists, pathologists, and clinicians develop novel strategies to prevent or treat infectious diseases.

Many exciting initiatives led by EIC
@abaumler.bsky.social on including New Voices in Microbiology and special topics issues - check it out! journals.asm.org/journal/iai

New preprint! We characterise the small, regulatory RNA Arp which controls DNA uptake and twitching motilty in A. baumannii. Led by our Dr Fergal Hamrock @hamrockfergal.bsky.social and in collaboration with @westermannlab.bsky.social and Mike Gebhardt's lab!

Expansion of tetM-Carrying Neisseria gonorrhoeae in the United States, 2018–2024 | NEJM During 2018–2024, the percentage of N. gonorrhoeae isolates carrying tetM, which confers tetracycline resistance, increased from less than 10% to more than 30% across the United States.

New @nejm.org report shows a rapid rise in tetM-carrying Neisseria gonorrhoeae strains in the U.S. jumping from <10% in 2020 to >30% by early 2024.
Why? Likely linked to our increased use of doxycycline both for STI treatment and DoxyPEP.
#MedSky #IDSky
www.nejm.org/doi/full/10....

Goodbye and good luck in graduate school, Kabita Kunwar!

David Holden's breakthrough or suing barcoding and transposon mutagenesis to identify negative selection mutants.

science.sciencemag.org/content/269/...

🍂 👿 Brown University has not Received NIH Grant Payments Since April
🧪
"Department of Health and Human Services (HHS) also told NIH to not communicate with the schools about 'whether or why the funds are frozen' "
fiercebiotech.com/

White House Eyes Rarely Used Power to Override Congress on Spending

Important story about OMB's plans with regard to appropriated funds. This is a big deal, both practically and constitutionally.

[Gift article]

www.nytimes.com/2025/06/17/u...

Two line graphs show NIH Outlays for Grants at Brown University. The left graph, "Outlay per month (USD)," shows monthly outlays from October (P01-P02) to June (P09) for fiscal years 2022, 2023, 2024, and 2025. The 2025 line (black) shows outlays around $15,000,000 from October 2024 to March 2025, then drops sharply to $0 in April 2025 and remains at $0 for May and June. Lines for previous fiscal years remain above $10,000,000 throughout the period. The right graph, "Percent of grants without an outlay," shows the percentage of grants without monthly outlays over the same period. The 2025 line (black) shows percentages below 10% until March 2025, then spikes to 100% in April 2025 and remains at 100% for May and June. Lines for previous fiscal years remain below 20%.

Two line graphs show NIH Outlays for Grants at Columbia University. The left graph, "Outlay per month (USD)," shows monthly outlays from October (P01-P02) to June (P09) for fiscal years 2022, 2023, 2024, and 2025. The 2025 line (black) shows outlays between $40,000,000 and $60,000,000 from October 2024 to March 2025, then drops sharply to approximately $20,000,000 in April 2025 and to $0 in May and June. Lines for previous fiscal years fluctuate but remain generally above $25,000,000. The right graph, "Percent of grants without an outlay," shows the percentage of grants without monthly outlays over the same period. The 2025 line (black) shows percentages below 20% until March 2025, then spikes to 100% in April 2025 and remains at 100% for May and June. Lines for previous fiscal years remain mostly below 20%.

Two line graphs show NIH Outlays for Grants at Cornell University. The left graph, "Outlay per month (USD)," shows monthly outlays from October (P01-P02) to June (P09) for fiscal years 2022, 2023, 2024, and 2025. The 2025 line (black) shows outlays between $10,000,000 and $20,000,000 from October 2024 to March 2025, then drops to $0 in April 2025 and remains at $0 for May and June. Lines for previous fiscal years show some variability but generally stay above $0, with some dips. The right graph, "Percent of grants without an outlay," shows the percentage of grants without monthly outlays over the same period. The 2025 line (black) shows percentages below 20% until March 2025, then spikes to 100% in April 2025 and remains at 100% for May and June. Lines for previous fiscal years show more variability than Harvard and Northwestern, with some spikes, as well, but returning to normal levels after.

Two line graphs show NIH Outlays for Grants at Northwestern University. The left graph, "Outlay per month (USD)," shows monthly outlays from October (P01-P02) to June (P09) for fiscal years 2022, 2023, 2024, and 2025. The 2025 line (black) shows outlays around $30,000,000 from October 2024 to March 2025, then drops sharply to $0 in April 2025 and remains at $0 for May and June. Lines for previous fiscal years remain above $25,000,000 throughout the period. The right graph, "Percent of grants without an outlay," shows the percentage of grants without monthly outlays over the same period. The 2025 line (black) shows percentages below 15% until March 2025, then spikes to 100% in April 2025 and remains at 100% for May and June. Lines for previous fiscal years remain below 20%.

NEW at grant-watch.us: Emma Mairson and Marian Jarlenski report on funding freezes at Brown, Columbia, Cornell, and Northwestern, that have received zero payments for #NIH grants since the start of April: grant-watch.us/posts/trends...

Where is here?

This is more than just lost grant dollars...this is patients in experimental treatments for incurable cancers having to stop their course of treatment.

It's patients with medical devices going unmonitored.

It's entire lines of groundbreaking science coming to a hard stop.

#DownWithDOGE

👏🏽👏🏽👏🏽🇨🇦🇨🇦🇨🇦

Medical Research Funding — Unbreaking How the administration is breaking the government, and what that means for all of us.

Comprehensive reporting of issues with US science funding. unbreaking.org/issues/medic...

#AcademicSky #EduSky