Werner Siemens Imaging Center

We’re thrilled that our researchers will present on microbiota-derived metabolites in cancer 🧫⚛️ at two meetings!

🇩🇪 Munich Metabolomics Meeting –
🗣 @sissid.bsky.social (Oct 10, 11:20)

🇨🇭 Swiss Metabolomics Society – Oct 10
🗣 Christoph Trautwein (14:40)
🔗 swiss-metabolomics.ch

👏 Good luck to both!

Greetings from Hannover! 🇩🇪

Our colleague Dr. Christoph Trautwein presents at the German Society for Metabolomics 🧪🧬 Talk: Multimodal metabolomics (NMR, timsTOF LC-MS, MALDI Imaging) in cancer 📅 Oct 2, 9:00–9:15 #Metabolomics #CancerResearch

Exciting science at #IMSIS2025! 🌟🇺🇸 Our colleague @sissid.bsky.social will present on multimodal metabolomic profiling to uncover biomarkers & pathways in endometriosis. 📍UC Davis, Sep 30, 13:30. Don’t miss insights into mass spectrometry imaging & women’s health! #Endometriosis #Metabolomics

First day of our 5th Day of Intravital Microscopy conference has started!
Organised by our Team Intravital Microscopy and the working group of the @wsic.bsky.social and iFIT Cluster of Excellence.
Already had amazing talks and are looking forward to many more ✨
#IvMic2025

🎓✨ Congratulations to Dr. Federica Bonanno on her successful defense! 👏

Her thesis, “Development and Radiolabeling of Structurally Distinct Pyrazolethiazole PET Tracers for Imaging of Alpha-Synuclein Aggregates”, marks an important step forward in molecular imaging of neurodegenerative diseases🧠🔬

Happy to share that our PhD Student Ragini Kushwaha will be presenting at the 7th UK Preclinical Stroke Symposium at Keble College, University of Oxford 🇬🇧✨

Title: “The role of Gai proteins in neutrophils and platelet-neutrophil complexes during ischemia reperfusion injury”

🗓️ Today ⏰ 11:30–11:45

Still feeling inspired after our time at TOPIM 2025 in Siena🇮🇹
We are excited for the work happening in theranostics 🧬💉

Congrats to Grace Mayuni for the Poster Award 🏆 and to Dimitri Stowbur as part of the winning Red Team👏

And of course, a huge thank you to the ESMI for their organizing work!

Day 2 at #TOPIM2025 🇮🇹✨

🧬 Grace Mayuni presenting her poster on enzymatically radiolabeled scFv fusion proteins (Poster Pitch II, Tue 16:30)

🎤 Dr. Dimitri Stowbur on L-DOS47 & the tumor microenvironment (Wed 17:15)

🦠 Marc Neumann on oncolytic virus therapy & ICI-based immunotherapy (Wed 17:35)

Hello from Siena 🇮🇹!

The WSIC is at TOPIM 2025 – "Theranostics: Pushing the Limits"

Kicking off our line-up, Francisco Reche-Pérez will present:

🗣️ Next-generation β-galactosidase targeting senescence radiotracers☢️💉

📅 Tue, Aug 26 | 17:35–17:50

Stay tuned for more from our team!

📰New Paper📰!

Our study: "PET-based immunomapping of intratumoral CD4⁺ cells to monitor acquired resistance to checkpoint inhibitors,☢️💉"

We present a non-invasive PET approach to map CD4⁺ T cells in tumors & track resistance to immunotherapy🧬.

🔗 www.science.org/doi/10.1126/...

WSIC Lab Celebrates Summer & Success!⛱️🍹

Cheers to our amazing team for a memorable #summerparty ☀️

Congrats to our 2025 awardees:
🏆 Dr. Laura Kuebler – Best Thesis
🍾 Marilena Poxleitner – Best Publication
🥇 Yasmin Al-Moufleh & Adrian Mannel -winner chefs of our food contest!🌮🍜

🗞️New paper!!

🧊Cryogenic tissue pulverization + lyophilization as a tool for multi-omics from a single mouse biopsy 🧬🧪

Takeaways:
✅ Preserves molecular integrity
✅ Reduces biological variability
✅Single sample multi-omics

🔗 www.nature.com/articles/s41...

Congrats to @laimziz.bsky.social & team🎉

What an event!
Huge thanks to the organizers and everyone who stopped by to chat and exchange ideas. I’m always excited to bring open, accessible conversations to non-scientific audiences - breaking down the barriers of complex science and medicine.
Truly enjoyed every moment! 😎
@wsic.bsky.social

🧪 We are happy to share a recent study by Gyuntae Bae and our #metabolomics team - using NMR spectroscopy and inflammatory profiling in long #Covid-19🫁 —reveals a persistent hyperlipidemic signature alongside low-grade progressive inflammation.

More info here🔗 link.springer.com/article/10.1...

Latest work by Georgy Berezhnoy and members of our metabolomics team 👏

🧠 Highlights:
• Stratified Parkinson's Disease by genetics (e.g. GBA), duration, and severity
• Identified potential biomarkers
• Linked metabolite patterns to dementia with Lewy Bodies

🔗: www.nature.com/articles/s41...

🧬New paper!

@sissid.bsky.social & co-authors explored microbiota-derived metabolites in ascites from ovarian and GI cancer patients. With 4D #metabolomics, they found shared profiles in advanced disease and links to immune markers like IL-10.
🔗 cancerandmetabolism.biomedcentral.com/articles/10....

WSIC at the 17th SEeON Conference✨

This morning, Eden Laing will be giving a talk on her PhD work!

🕘 9:45–10:45 | Session on Gut Microbiota Recovery

Eden’s work showcases innovative approaches at the intersection of imaging and microbiome research🔬🧪🦠

✨Don’t miss it!

#SEeON2025

🧪 Day 2 at #Metabolomics2025 in Prague 🇨🇿!

Check out Poster Group B (June 24–25):

@sissid.bsky.social -P2058B: NMR + MALDI reveal metabolic heterogeneity in endometriosis

Gyuntae Bae – P2059B: Lipidomics + cytokines uncover post-COVID inflammation

Come meet our PhD students behind the science!

🎉 Heading to #Metabolomics2025 in Prague!
Join us Mon (June 23) at the Welcome Reception & Tues (June 24) A.M. break/lunch.

📍#1063A – Dr. Christoph Trautwein: NMR in solid cancers
📍#1074A – @laimziz.bsky.social : Tumor microenvironment via spatial metabolomics

#NMR #CancerResearch

🎉 Some exciting news!

Our PhD student, Remy Chiaffarelli's abstract for #ISMRM2025 scored in the top 5% — earning him a special award🎖️— and was also selected by the Annual Meeting Program Committee (AMPC) for further recognition.

Congratulations Remy👏

@ismrm.bsky.social

Gina Dunkel from our department will be presenting a poster at #EACR2025!🇵🇹

The congress brings together researchers from all over the world to share breakthroughs in cancer research. If you’re there, don’t miss it!

2025.eacr.org

#EACR2025

🧠 Just published: our latest paper explores why great segmentation doesn't always equal accurate therapy detection in stroke research. Key finding: Training nnU-Net with probabilistic GMM labels boosts therapy response accuracy.

Dive in 👉 www.sciencedirect.com/science/arti...

#AI #StrokeResearch

Greetings from South Korea🇰🇷!

Proud to share that two of our members are presenting their work at the 🧠Brain & Brain PET 2025 conference in Seoul!

Coming up, Prof. Dr. Kristina Herfert will present on - "Functional dynamics through a molecular lens: Imaging connectivity in preclinical models".

5th Day of Intravital Microscopy - German BioImaging Intravital microscopy (IVM) enables the observation and precise quantification of cellular processes within native tissue microenvironments, with resolutions unmatched by other techniques. This powerf...

🚨Registration now open!
Join us for the 5th Day of Intravital Microscopy on 18-19 September 2025 in Tübingen. Organized together with @wsic.bsky.social.

👉Don’t miss out and register now: gerbi-gmb.de/event/5th-da...

#IVMIC25

📢New paper alert!

📝Co-authored by Yan Ma & Laura Kübler

This study highlights the importance of carefully selecting breathing methods & anesthesia in combined PET/fMRI studies, as they can significantly impact the accuracy & interpretation of brain imaging data.
🔗 link.springer.com/article/10.1...

Hello Tübingen 👋

Join us tonight in📍Neckawa where @bettina-weigelin.bsky.social will be speaking at Pint of Science🍻

Topic - "Our Body":Von Abwehrkräften & Genboten – Wenn Immunzellen kämpfen und Viren Pakete liefern.

(German only 🇩🇪)

For more info: pintofscience.de/event/our-bo...

Congratulations to Dr. Ran Sing Saw, who successfully defended her doctoral thesis!!🎓🎊

Her defense, titled "Towards PET Imaging of alpha-Synuclein Aggregates : Preclinical Evaluation of Potential Alpha-Synuclein PET Tracers," focused on the development of tracers in synucleinopathies🧠🔬

Catch WSIC at #iSRS2025 !🌏 🇦🇺

◽Jonathan Cotton speaks on ⁶⁴Cu-labelled α-fucosidase for imaging #senescence 🧪☢️

◽Federica Bonanno shares a poster on α-synuclein #PET ligands🧠☢️

If you're attending, feel free to stop by!!

We look forward to engaging with the #radiopharmaceutical research community!

I am so jealous but grateful that @Remy Chiaffarelli and @kimiasm.bsky.social are representing our lab so well. If you are attending the @ismrm.bsky.social in Hawaii, go see these 2 rock stars. 💪✌️👏🌺

Aloha from WSIC 🌺

We're excited to share that our PhD students, Remy Chiaffarelli and @kimiasm.bsky.social , will be presenting their work at ISMRM 2025 in beautiful Honolulu, Hawaii! 🌊🌴

Stay tuned for more research from our lab at ISMRM 2025. 🧲🔍🧬 #ISMRM2025 #WSIC #PhDLife #MRIresearch