Context-aware geometric deep learning for RNA sequence design https://www.biorxiv.org/content/10.1101/2025.06.21.660801v1
22.06.2025 04:46 β π 2 π 1 π¬ 0 π 0
Presenting RISoTTo, a molecular context-aware model for RNA sequence design, building on our work with PeSTo (for protein binding interface prediction) and CARBonAra (for protein design).
π Preprint: www.biorxiv.org/content/10.1...
π» Code & more coming soon!
#RNAdesign #RNAbiology #AI4Science
22.06.2025 09:02 β π 18 π 4 π¬ 1 π 2
Carbonara - a Hugging Face Space by LBM-EPFL
Interactive demo of carbonara
Inspired by @simonduerr.bsky.social at ERC'24 I built and deployed our sequence redesign model called CARBonAra on @hf.co.
The model is aware of any biomolecular context and performs on par with ProteinMPNN (see paper)
Check it out here: huggingface.co/spaces/LBM-E...
@lbm-epfl.bsky.social
13.12.2024 15:23 β π 3 π 1 π¬ 1 π 0
Absolute π
12.12.2024 13:54 β π 0 π 0 π¬ 0 π 0
Three BioML starter packs now!
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
03.12.2024 03:27 β π 147 π 60 π¬ 16 π 6
@benediktsinger.bsky.social
03.12.2024 07:21 β π 1 π 0 π¬ 0 π 0
I felt the same when I saw so many people working on enzyme design at EuRosettacon last week
21.11.2024 09:57 β π 1 π 0 π¬ 0 π 0
Dr. Norbert Perrimon's lab at Harvard Medical School researches functional genomics, cell circuitry, and tissue homeostasis in Drosophila melanogaster.
https://perrimon.med.harvard.edu/
Welcome to the RNA networks lab! At the UK DRI at King's College London, Francis Crick Institute and Kemijski inΕ‘titut (National Institute of Chemistry) in Ljubljana πͺπΊ
Professor | Director, UQ Centre for RNA in Neuroscience | Queensland Brain Institute | Noncoding RNA and memory; RNA and DNA modification in the brain.
PhD student in the Soller lab (University of Manchester )π©π»βπ¬ mRNA Methylation|Cap methylation
ICREA Professor & Group Leader - Epitranscriptomics & RNA Dynamics @CRGenomica. Biochemist and bioinformatician. #RNAmods #nanopore #ribosome #tRNA #inheritance. Mom of 3. Piano, beach vball, hiking
Website: novoalab.com
Professor of Biochemistry at the University of Toronto. Studies mRNA processing, mRNA nuclear export, mRNA translation, genomic evolution, junk DNA, junk RNA.
https://www.palazzolab.com/
The GrailleLab is interested in understanding how RNA post-transcriptional and/or protein post-translational modifications are written, erased and read as well as how they influence mRNA decoding by ribosome for protein synthesis.
Nucleic Acid Chemistry Lab
RNA technologies. hesselberthlab.org
RNA Biologist - Bloomberg Distinguished Professor of mRNA Biology and Therapeutics. Director of the Hopkins RNA Innovation Center. Cofounder - Tevard Biosciences. Cofounder - Alliance for mRNA Medicines. Cofounder - Foundation for mRNA Medicines.
I'm a scientist! Asst Prof at Univ of Delaware | RNA biochemistry, RNA modifications, (metallo)enzymology, structural biology, and chemistry | Postdoc at UCSF | PhD at UCBerkeley | he/him
mugridgelab.org
Circular RNAs and RNA modifications, Assistant Professor at Yale University
Structural biologist, biochemist | Prof @EmoryChem
| Protein synthesis, RNA, toxin-antitoxins |
https://dunham.emorychem.science/
Assistant Prof @ Yale MCDB; RNA enthusiast; washed up college athlete; kid wrangler x2 (not necessarily in that order)
Molecular Biologist. Transcription aficionado. Birder. Assistant Professor of Biological Sciences, University of Delaware
Scientist interested in the RNA biology underlying brain development and synaptic plasticity
Postdoc @ NYU | Ph.D. @ Duke University Biochemistry | UVa Alum | he/him/his π³οΈβπ
Assistant Professor Dept. Pharmacology. Northwestern University, Chicago. RNA biologist. RNA-modifying enzymes. Protein synthesis.
https://www.helmholtz-munich.de/en/ife
