Open Ephys

Learn how to use the new Acquisition Board and GUI with our training team in a remote training 📚

Tailored to your experiments, we cover everything you need to help you get started with our ephys data acquisition equipment and software 💻

Take a look at open-ephys.org/training for more details 🔍

The low-profile SPI Headstage 64ch is ideal for promoting naturalistic behavior, as it significantly reduces torque on the animal's head in comparison with the SPI Headstage 32ch version 🌱🐁

Each headstage includes an embedded 9-axis IMU that senses absolute orientation, from which you can get pitch, yaw, and roll movements and drive our torque-free SPI commutator 🌀

We have three variants of our 3D capable SPI headstages: 32ch unipolar, 64ch unipolar low-profile and 16ch bipolar 📈

The Acquisition Board works seamlessly with three types of 𝟯𝗗 𝗰𝗮𝗽𝗮𝗯𝗹𝗲 𝗵𝗲𝗮𝗱𝘀𝘁𝗮𝗴𝗲𝘀 to follow your subjects’ every mooove 🕺💃

Headstage-mounted inertial measurement units (IMUs) can be used to acquire head orientation data based on an animal’s head movements 🐭🧭

Along with our new-and-improved GUI, the 𝟯𝗿𝗱 𝗚𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝗼𝗻 𝗢𝗽𝗲𝗻 𝗘𝗽𝗵𝘆𝘀 𝗔𝗰𝗾𝘂𝗶𝘀𝗶𝘁𝗶𝗼𝗻 𝗕𝗼𝗮𝗿𝗱 is part of a complete platform for multichannel ephys.

✅ Scales to 512 channels
✅ Prevents cable twisting in freely moving recordings
✅ Ships globally from Lisbon

Buy it now at open-ephys.org/store

𝗢𝗽𝗲𝗻 𝗘𝗽𝗵𝘆𝘀 𝗚𝗨𝗜 𝘃𝟭.𝟬

A major upgrade to the most flexible software for ephys data acquisition.

✅ Handles 10k+ channels in parallel
✅ Includes dozens of UI/UX improvements
✅ Streams data from Open Ephys/IMEC/Intan/Kontex/NI hardware

Try it out today open-ephys.org/gui

Acquisition Board — Open Ephys The 3rd generation of our Acquisition Board captures up to 512 ch of neural data and absolute head orientation from our 3D capable headstages to drive a torque-free commutator for tangle-free naturalistic recordings.

15 years ago, we created the first prototypes of two tools that make multichannel ephys more affordable and scalable. Today, there are 2k+ Open Ephys Acquisition Boards in the field and 500+ pubs using the Open Ephys GUI. Both tools have now been rebuilt for the future of neuroscience.

#OpenEphys

💥 GOSH Community Council nominations are open! 💥
Want to shape the future of GOSH + open science hardware? Know someone who should? Step up - or nominate a fellow leader.

🕒 ~6 hrs/month
🌍 New & longtime GOSHers welcome!
🔗 goshcommunity.limesurvey.net/252574?lang=en

...all due to passion and the enthusiasm of the wonderful TAs and lecturers that make TENSS happen (only some with handles here): @pgupta-cshl.bsky.social @open-ephys.org @antblot.bsky.social @brunopichler.bsky.social @mtkostecki.bsky.social @neuroetho.bsky.social @alecamera.bsky.social

🚩What’s next? We are actively developing an Open Ephys GUI ONIX plugin to expand software options for ONIX users. Keep your eyes peeled for a pre-release version in July!

Release v0.6.0 · open-ephys/bonsai-onix1 What's Changed 🎉 New Features Add support for i2c multibyte access and make polledbno use it by @aacuevas in #456 Aggregate changes targeting controller gateware version 2.0 by @jonnew in #443 Add...

📑Here’s the full change log: github.com/open-ephys/bonsai-...
And the docs on how to update (1) the controller firmware (bit.ly/4kgZxpt) and (2) the Bonsai package (bit.ly/4eyphfK)

🔄 Update to ONIX controller firmware v2.0 and the OpenEphys.Onix1 Bonsai package v0.6.0 to to get ~3x higher temporal resolution for behavioral tracking on neuropixels headstages, faster hardware communication, and improved system stability.

📢 We are excited to announce a substantial update to ONIX hardware and software that delivers significant performance improvements and enhanced system reliability.
#OpenEphys #ONIX #Bonsai

Stacks of GOSH stickers on a table top at a GOSH event

The 🌍🔬 Gathering for Open Science Hardware 🔬🌍 is a global community making science tools open, accessible, and ethical. We share designs for everything from microscopes to sensors, and we hope you'll join us!

🌟 Learn more: openhardware.science
🌟 Join the conversation: forum.openhardware.science

Optics and Microscopy Workshop 2025 May 9-11th, Nencki Institute We are happy to announce the fourth edition of our Optics and Microscopy Workshop! The workshop will be a thorough, hands – on introduction to optics and microsco…

We are super happy to announce the 4th edition of our Optics and Microscopy Workshop that will be held May 9-11 th at Nencki! Join us to learn optics - from basics up to building your fluorescent microscope! More info here -https://nenckiopenlab.org/optics-and-microscopy-workshop-2025/

ONIX analog and digital expansion board, with commutator and Neuropixels headstage. Monitor showing the workflow in Bonsai using the OpenEphys.Onix1 package and the Open Ephys GUI Probe Viewer plugin.

Are you using Neuropixels probes with our ONIX headstages?

🛠️ We’ve just uploaded a tutorial that details how to stream Neuropixels data from Bonsai to Open Ephys GUI so you can use its high-density probe visualizers while retaining the flexibility of Bonsai.

#OpenEphys #Bonsai #ONIX #Neuropixels

The Transmitter datasets survey What datasets do you mostly rely on? We want to hear from you.

We want to hear from you! Given recent changes to publicly available data, @thetransmitter.bsky.social wants to know what datasets are most important to the neuroscience community. What datasets do you use in your research?

#neuroskyence

thetransmitter.typeform.com/datasets?utm...

🤔 Want to use the Miniscope in your experiments?
🧐 Are you already working with it, but want to learn how to harness its full potential?
💡 Attend our free virtual event with Ceci Herbert @chucklescience.bsky.social from @open-ephys.org.
📅 Thu, March 20 at noon (ET) via Zoom
Register 👇

Workshop: Science through Computation · Luma The Computational Motifs Initiative is coming to San Francisco! Together with Pebblebed, we’re hosting a 2-day hackathon on 26-27 March connecting builders and…

We (www.compmotifs.com) are coming to SF!

Together with Pebblebed, we’re hosting a 2-day hackathon on 26-27 March for builders and scientists across disciplines to build new methods and tools for the computational and natural sciences. Join us: lu.ma/t5yik06g.

Reposts will be much appreciated!

✅Save your spot at our next hybrid workshop and learn how to dig into open-source tools for data acquisition and analysis, including the Miniscope!
🗓️Thu, March 20 at noon (ET) via Zoom
🧑‍🔬Join our expert Ceci Herbert
@chucklescience.bsky.social
from
@open-ephys.org

👇Link & details
#openscience

2025 Allen Institute Modeling Software Workshop Join us at the 2025 Allen Institute Modeling Software Workshop for a hands-on opportunity to learn how to use open-source software modeling tools developed by the Allen Institute and our collaborators at UIUC.

Training opportunity! The 2025 Allen Institute Modeling Software Workshop: learn how to use #opensource software modeling tools.

Apply by March 15: alleninstitute.org/e...

@AllenInstitute@mastodon.world @alleninstitute.bsky.social @AllenInstitute

#OpenEphys #OpenEphysGUI

Stay tuned for an update about the official release—we just need to put the finishing touches on the documentation before that’s announced. In the meantime, we would love to hear any feedback you have about the latest preview (v1.0.0-alpha.3)!

We’ve put a lot of effort into making this version more robust, performant, and user friendly—it’s something we’re proud to call “version 1.0.” You can find a summary of the major enhancements here: open-ephys.github.io/gui-docs/Use...

Update preview of Open Ephys GUI 1.0

The Open Ephys GUI is the world’s only cross-platform, plugin-based application for high-channel-count electrophysiology. A preview of the long-awaited version 1.0 is now available to download: openephys.jfrog.io/ui/native/GU...

⏰ Last days to apply!!⏰

This hands-on course covers:
🦠 Flies/Zebrafish – Optogenetics, 2P imaging
🐭 Mice – 2P/3P imaging, Neuropixels, closed-loop behavior

📅 June 8-27, 2025 | Champalimaud, Lisbon
⏳ Apply by March 7
🔗 loom.ly/OMvqMcE

Picture of a screen showing NP a recording in OpenEphys

We are very happy and proud to have helped the Bacci team get their first Neuropixels recordings using @open-ephys.org in @institutducerveau.bsky.social . 🚀

Null and Noteworthy, relaunched: Probing a schizophrenia biomarker This edition of Null and Noteworthy—the first for The Transmitter—highlights new findings about the auditory steady-state response in people with schizophrenia that, all within one study…

New newsletter alert! We're relaunching Null and Noteworthy, a monthly roundup about null results and replications in neuroscience research. This month: A failed replication of a potential schizophrenia biomarker.

By Laura Dattaro

#neuroskyence

www.thetransmitter.org/null-and-not...

🧠NEUROSCIENCE NEEDS MAKERS!🔧
🚨LAST SPOTS for our workshop on BONSAI_RX for systems and behavioral neuroscientist.
5th to 7th June 2025, UC-Biotech, Coimbra (Portugal).

Register here (be fast! first come first served!):
docs.google.com/forms/d/e/1F...

@open-ephys.org @open-neuroscience.com

Release v0.4.4 · open-ephys/bonsai-onix1 What's Changed 🚀 Performance Improvements Tie lifetime of oni.Context to that of ContextTask by @jonnew in #409 📄 Documentation Add voltage conversion equations to Neuropixels DataFrame docs by ...

📢 Update notice

🔄 Make sure to update to version 0.4.4 of our ONIX Bonsai package (OpenEphys.Onix1) for performance improvements.

Here is the change log:
github.com/open-ephys/b...

And the docs on how to update:
open-ephys.github.io/bonsai-onix1...

#OpenEphys #ONIX #Bonsai