Han de Jong

I am incredibly excited and proud to share my first preprint from my postdoc! Thank you to all of the co-authors for all your hard work!
Check out the paper for big insights into plasticity mechanisms in navigation circuits! And surprising motifs for inhibitory synaptic plasticity!

🚨Our preprint is online!🚨

www.biorxiv.org/content/10.1...

How do #dopamine neurons perform the key calculations in reinforcement #learning?

Read on to find out more! 🧵

A flexible hippocampal population code for experience relative to reward - Nature Neuroscience Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵

www.nature.com/articles/s41...

What dopamine teaches depends on what the brain believes - Nature Neuroscience How does the brain learn to predict rewards? In this issue of Nature Neuroscience, Qian, Burrell et al. show that understanding how dopamine guides learning requires knowledge of how animals interpret...

Nature Neuroscience

What dopamine teaches depends on what the brain believes

www.nature.com/articles/s41...

🧠✨ Symposia submissions are NOW OPEN for Dopamine Meeting 2026! @DopamineSociety
📍Sevilla, Spain
📅 Open: May 1, 2025
⏳ Deadline: June 16, 2025
Spread the word — don’t miss out!
#Dopamine2026
dopaminesociety.org

I’m excited to present a new research project at #cosyne2025 this year!

High Sensitivity Vibration Sensor

It's not perfect, but this works: www.te.com/en/product-C...

Our new study: Dopamine in the tail of the striatum facilitates avoidance in threat–reward conflicts. Congrats Iku-Tsutsui Kimura, Melissa Tian and others! Led by Mitsuko Watabe-Uchida. www.nature.com/articles/s41...

New Pre-Print led by @emilyprevost.bsky.social Glutamate-dopamine, nonglu-dopamine, and glu-only neurons and neurotransmitters they use have dissociable contributions to motivated behavior. Important to segregate DA subcell-types to better understand the many motivation-related functions of DA

Your use of the term "average" in this analysis implies that the tax savings are normally distributed. I doubt that is true, a few long-term home owners reap all the benefits. Young families pay all the tax.

The time course and organization of hippocampal replay The mechanisms by which the brain replays neural activity sequences remain unknown. Recording from large ensembles of hippocampal place cells in freely behaving rats, we observed that replay content i...

1/19 I’m thrilled that my postdoctoral work, with John Widloski and David Foster is now out in @science.org, along with a wonderful preview by Daniel Bendor!

Help #neurosky #neuroskyence

Are you (or do you know) someone studying the transcription factor Ascl4/Mash4? 🧠 #neurodevelopment #differentiation #neurons #wiring

N.b. This is not the same as the acyl CoA synthetase protein ASCL4

I have some questions 💡

Please share! 🙏

My paper is out!! 🎉

"Opponent control of reinforcement by striatal dopamine and serotonin", @Nature

Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain

THREAD ⬇️

1/n

Thank you for helping your trainees out! Honestly, it feels like a lot to ask! I wish every university would just use Interfolio.

Happy birthday to both of you!