Simon Michaeli

We had a fab lab trip last week 🌻

Long in the making, but happy to present the Chlamydomonas chlororibosome!
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵

#transgenerational transmission of a core #microbiome that protects against downy mildew from soil to #phyllosphere

Fantastic and important study by @jellespooren.bsky.social @rlberendsen.bsky.social
@cornepieterse.bsky.social
academic.oup.com/ismej/advanc...
#plantscience

New review from P Genschik’s team in
@jxbotany.bsky.social 🧬 A fresh look at the huge diversity and functions of plant F-box proteins.
👉 Open questions & new perspectives for 🌱 biology.
▶️https://academic.oup.com/jxb/advance-article-abstract/doi/10.1093/jxb/erag074/8475508?redirectedFrom=fulltext

"The most uncomfortable part for me is that I no longer think that scientific research will resolve the crises that we face."

"I keep doing research not because I think it will save us, but because it would be a form of surrender to stop seeking understanding."

Beautiful #preprint on a novel regulator of plant #autophagy from the @cnaumann123.bsky.social lab. How do plants regulate #autophagosome size??? ER-PM contact sites and Can1 seem to be key! www.biorxiv.org/content/10.6...

Our own ‏Dorothy Matiki‏ presented her research (on autophagy in 🍅 ripening) impressively and earned her M.Sc. title! 🎉🍾

Soon Dorothy will meet the @weizmanninstitute.bsky.social Doctoral studies committee to (hopefully) approve her joining the lab of Prof. ‏Michal Sharon‏.
All the best Dorothy!

Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate Polyamines are often associated with ribosomes and are thought to stabilize their integrity. In Arabidopsis, the polyamine thermospermine (tSpm) affects xylem cell fate. tSpm induces translation of SU...

In @science.org this week, thermospermine affects ribosome methylation, which in turn regulates translation of xylem development proteins www.science.org/doi/10.1126/...

#plantscience

Apusomonad rhodopsins: A new family of ultraviolet to blue light–absorbing rhodopsin channels | PNAS Apusomonads are sediment-dwelling bacterivorous protists that are sister to all Opisthokonta. They have been found to show a negative phototactic r...

Apusomonad rhodopsins: A new family of ultraviolet to blue light–absorbing rhodopsin channels www.pnas.org/doi/full/10....

#SaturdayVibes

New year, new preprint! 🎊

We are excited to share our recent work on #E3 ligase regulation in #metabolism!

www.biorxiv.org/content/10.6...

#ubiquitin #targetedproteindegradation #chemicalbiology

1/6

a black background with the word idiocracy written in white letters . ALT: a black background with the word idiocracy written in white letters .

Dear @dfg.de So, I will spend months writing a grant and you will let people judge it with AI tools that are trained on predatory journals like Frontiers, MDPI or alike that are practically not peer-reviewed??? Is this how you will select cutting edge science??? #idiocracy

Fig. 1 (shortened, full legend in paper): Complexity of gynoecium development shown with confocal microscopy imaging. (A) Meristematic stages of floral development in which the inflorescence meristem (IM) is observed; from stage 3, the sepal primordia (asterisks) are observed; in stage 4, the developing sepals (asterisks) partially cover the floral meristem (FM); and in stage 5, the FM is completely covered by the sepals. (B) Stage 6 in which the gynoecium is established with the appearance of the primordium of the gynoecium. (C) In stage 7, the middle and lateral domains can be differentiated (marked by dotted lines). (D–H) Longitudinal view of the gynoecium from stage 8 to 12. At stages 8 and 9, the gynoecium grows as a hollow tube and the valves and young replum can be seen. (F and G) Longitudinal view of stage 10 and 11 gynoecia showing the replum and valves. (H) Mature stage 12 gynoecium showing the stigma, style, and ovary, the latter formed by the valves and replum.

🌸 Flowering Newsletter Review 🌸

López-Gómez et al. review the role of protein–protein interactions in flower and fruit development and discuss the latest techniques to study them.

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪 @defolter-lab.bsky.social

Why are so many plant viruses phloem-restricted? New work from Xueping Zhou’s lab reveals how this tissue tropism is determined in a geminivirus — and why phloem confinement can turn out to be an evolutionary advantage! www.nature.com/articles/s41... 🌱🦠🚷🅿️🛫🌱

Our work now on @jxbotany.bsky.social. Make sure you add some Cas13a fluorescent virus detection to your Christmas lights ✨️

Dynamic ASK1 proximity networks uncover SCF-dependent and noncanonical roles in ABA and drought adaptation Plants rely on rapid proteome remodeling to withstand fluctuating environmental conditions, yet how the ubiquitin system dynamically coordinates these multilayered responses remains unclear. Here we d...

Excited to share our latest work to close out 2025: Dynamic ASK1 proximity networks uncover SCF-dependent and noncanonical roles in ABA and drought adaptation🌱 With @justinwwalley.bsky.social , we map how ASK1/SKP1 dynamically rewires protein networks during stress www.biorxiv.org/content/10.6...

Researchers developed a #CRISPR-based method that's user-friendly, extraction-free, 15 min protocol for on-site #virus #detection using a portable fluorescence viewer and a mobile #phone camera directly from RNA of several crop species, including #tomato, #cucumber, and #rapeseed. 👉 bit.ly/4p6Jo8t

A 1.25 A!!! cryo EM structure of rubisco.

Christmas 🎄 and Hanukkah 🕎 celebration in Hala's (Dr. Khamesa-Israelov) place with all group members. What a treat 🥂🍻🍰

Raffinose induces autophagy to promote the growth of Arabidopsis Thaliana - BMC Plant Biology Background Plant growth depends on the integration of environmental signals and nutrient availability. Under stress conditions, growth is often attenuated to prioritise defense, creating a trade-off b...

Excited to share our work about autophagy and raffinose. So proud of Sahar Magen for doing a great job and grateful for all the people who helped bring this work to light.
link.springer.com/article/10.1...

Christmas 🎄 and Hanukkah 🕎 celebration in Hala's (Dr. Khamesa-Israelov) place with all group members. What a treat 🥂🍻🍰

Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

The Clavel Group is recruiting a new postdoc for two possible projects dealing with plant-virus interactions and selective autophagy! More (wordy) details below ⬇️🌱🦠

When the localization of a protein you thought you know well still manages to surprise you... 😯🤔☘️

#fluorescenceFriday by postdoctoral fellow Dr. Hala Khamesa-Israelov @volcaniinstitute.bsky.social

Blue light decreases ER Ca²⁺ in stomatal guard cells, with refilling in the dark. Our new @newphyt.bsky.social study shows how ER Ca²⁺ shapes cytosolic Ca²⁺ dynamics
doi.org/10.1111/nph....

Narcissus

When the localization of a protein you thought you know well still manages to surprise you... 😯🤔☘️

#fluorescenceFriday by postdoctoral fellow Dr. Hala Khamesa-Israelov @volcaniinstitute.bsky.social

May their words reach politicians‘ ears…

Tenure Track Professorship (W1 with Tenure Track to W3) in “Molecular Biology" (f/m/d) - Heidelberg job with Universität Heidelberg | 12850668 The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a   Tenure Track Professors...

Please RT‼️ #TenureTrack position @zmbh.uni-heidelberg.de one of the best #proteostasis research centres in the world. www.nature.com/naturecareer...

Check out our latest paper. Very glad to see this one finally out. Fantastic work by @charlotte-dlslle.bsky.social . Learn more about MBAP proteins and their roles in brassinosteroid signaling. www.sciencedirect.com/science/arti...