IECB Bordeaux

🚨 Fully funded PhD position in plant & structural biology! Join the @eliastahl.bsky.social lab in collaboration with our team. Exciting project on protein structure/function in plants 🌱. Contact us for details!
#PlantBiology #StructuralBiology #PhDposition @iecb.bsky.social

Looking forward to the demo of the @abberior.rocks #MINFLUX in few weeks in Bordeaux (organised by @iins-bordeaux.bsky.social and hosted by @iecb.bsky.social)

Deux nouveaux microscopes pour aller au cœur du vivant La plateforme de cryo-microscopie électronique à l’Institut européen de chimie et biologie (IECB) est renforcée par l’acquisition de deux nouveaux microscopes, Glacios 2 et Talos L120. Ces équipements de pointe offrent aux chercheurs une capacité unique pour explorer l’architecture moléculaire et cellulaire avec une précision inédite, positionnant Bordeaux comme un acteur majeur dans ce domaine en France.

L’Institut européen de chimie et biologie @iecb.bsky.social est renforcé par l’acquisition de deux nouveaux microscopes de pointe, offrant aux chercheurs une capacité unique pour explorer l’architecture moléculaire et cellulaire avec une précision inédite :
www.u-bordeaux.fr/ac...

Indeed, we are looking of a PhD student at the interface between chemistry, biophysics and biology to work on light induced LLPS. join us at @iecb.bsky.social in Bordeaux !

We are recruiting!
A three year PhD position @iecb.bsky.social and @lbm-bordeaux.bsky.social to study lipid recognition by plant receptor-like kinases. A collaborative project with the team of @pierre-maisonneuve.bsky.social. Join us in the beautiful city of Bordeaux!

emploi.cnrs.fr/Offres/Docto...

Only one week left to apply 🤓!!!

BRAF oncogenic mutants evade autoinhibition through a common mechanism Uncontrolled activation of the rat sarcoma (RAS)–extracellular signal–regulated kinase (ERK) pathway drives tumor growth, often because of oncogenic BRAF mutations. BRAF regulation, involving monomeri...

🎉 New paper out in Science!
In collaboration with Marc Therrien’s lab, we show how oncogenic BRAF mutants adopt a pre-active conformation, escaping auto-inhibition and driving RAS–ERK pathway activation in cancer.
Proud to have contributed! #IRIC #CBMN @iecb.bsky.social @univbordeaux.bsky.social

Only two weeks left to submit your application!!!

Fellow ladies in science, as part of the disappearing species of international female scientists in France and perhaps every/elsewhere, I want to bring your special attention to our institute's open call for group leaders 👩‍🔬🦠🧪🔬🤓!!! Come join me in doing some coolicious science here 🙏!

We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to submit your application 🤓!!!

Molecular basis for the calcium-dependent activation of the ribonuclease EndoU - Nature Communications Eucaryotic EndoU are endoribonucleases that require calcium ions to cleave RNA substrates. Here, the authors solved the structure of calcium-activated human EndoU and proposed a structural model for U...

Check out the latest study from our Campagne Lab on the structure and calcium-dependent activation of the ubiquitous ribonuclease EndoU 🤩! Congratulations to all the authors 👏👏👏

www.nature.com/articles/s41...

Deciphering the formation of cooperative multicellular biofilms Bacterial films are a hazard throughout the healthcare system, and as antibiotic resistance increases there is an even greater imperative...

🦠 Most #bacteria form #biofilms, protective communities that resist #antibiotics.

Petya Krasteva's research explores the structure & behaviour of these biofilms, hoping to develop new #antimicrobial strategies.

Read more 👉 buff.ly/YajqauG

@krastevalab.bsky.social @iecb.bsky.social @CNRS.fr

Excited to join 2025 Korean Chemical Society 135th General Meeting &Exhibition this week! Always a pleasure to catch up with colleagues and reconnect with lab alumni. Thank you, Sung Hyun @yoo-bios-lab.bsky.social for the fantastic welcome in Korea — truly appreciated!
@iecb.bsky.social
#ChemSky

We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!!

Join us this Friday, April 4th, for an afternoon minisymposium on protein structure and dynamics in disease! The place is as usual our IECB amphitheater!

Check out the latest work from our Guichard Lab creating cell-permeable, macrocyclic peptide-oligourea foldamers to target hDM2 and restore p53 signaling in cancer cells 🤩🧪⚗️!

Solid-state NMR Observation of Chitin in Whole Cells by Indirect 15N Detection with NC, NCC, CNC and CNCC polarization transfers Chitin is the most important nitrogen-containing polysaccharide found on Earth. This polysaccharide is a polymer of an N-acetylglucosamine and it is a…

Our work on indirect 15N chitin detection in whole cells by Solid-State #NMR with Laurence Delhaes, work done at
@iecb.bsky.social with @cnrs.fr and @univbordeaux.bsky.social
www.sciencedirect.com/science/arti...

It was really good to host the French EPR society meeting in Bordeaux at @iecb.bsky.social

Molecular Distinction of Cell Wall and Capsular Polysaccharides in Encapsulated Pathogens by In Situ Magic-Angle Spinning NMR Techniques Pathogenic fungal and bacterial cells are enveloped within a cell wall, a molecular barrier at their cell surface, and a critical architecture that constantly evolves during pathogenesis. Understandin...

Check our study in press in JACS on the use of solid-state #NMR to investigate polysaccharides in encapsulated pathogens, demonstrated on #Cryptococcus neoformans. Congrats to Alons Lends and all coworkers
@iecb.bsky.social @cnrs.fr @univbordeaux.bsky.social
pubs.acs.org/doi/10.1021/...

It was such a pleasure and privilege to have Prof Sabine Flitsch from Manchester university presenting today at our IECB seminar series @iecb.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social

Don't forget to join us today!

Guanidinium‐Stapled Helical Peptides for Targeting Protein‐Protein Interactions Peptide stapling has emerged as a versatile approach in drug discovery to reinforce secondary structure elements especially α-helices and improve properties of linear…

Happy to share our work on guanidinium-stapled peptides, now published in @angewandtechemie.bsky.social! A versatile method to stabilize peptide helices for precise protein surface recognition. Congrats to the team and special thanks to Morgane Pasco! 👏
🔗 doi.org/10.1002/anie...
@iecb.bsky.social

We just received a New EPR spectrometer installed in Bordeaux @iecb.bsky.social 🥰. Table top Xband.

Join us in March for two days of EPR-driven science courtesy of our in-house EPR whiz @fichoulab.bsky.social ! Program and more information coming soon 🤓!

I am starting to assemble a starter pack with past and current members of our institute @iecb.bsky.social

Send me a message if you wish to be included.

go.bsky.app/L86XUk1

Join us next week on Friday the 7th, at 11 am, in our IECB amphitheater to learn a whole lot on the design and applications of enzyme cascades for organic synthesis 🤓🧪👩‍🔬⚗️! Guest speaker Prof. Sabine Flitsch from the University of Manchester 🤩!!!

www.iecb.u-bordeaux.fr/evenements/i...

Already here with plenty of followers 😊! Keeping an open mind ✌️🤓

Join us tomorrow at 11 am at the IECB amphitheater to learn more on the physiology of phospholipids 🤩! Guest speaker @yvonjaillais.bsky.social from the ENS Lyon 🤓

Congratulations to our @iecb.bsky.social and MFP colleague Nicolas Reyes for his medal from the French académie des sciences (médaille de la section de Biologie moléculaire et cellulaire, génomique).
@univbordeaux.bsky.social @cnrs.bsky.social

It was an honor to host Frances Separovic at IECB @iecb.bsky.social for a special symposium and later for the ceremony of her Honoris Causa of Bordeaux University @univbordeaux.bsky.social ; awarded for her amazing work in #NMR science as well as her contribution to promote #womeninscience
#NMRchat