Diamond Lab

‼️Diamond Lab is considering potential a new postdoctoral researcher. If you have strong interests in microbiomes, metagenomics, machine learning, or rumen biology drop us a line and shoot us a CV!

We Love it!! And in our colors too

Love these!!! Now let’s see some communities in watercolor

Think about all the amazing chemotropic microbes that must support this system!!! I hope they took samples

Science x Art Science x Art - Innovative Genomics Institute (IGI)

Did you know that the illustrations in our resources like CRISPRpedia are free to use for non-commercial, educational purposes? Check out our Science x Art page to see a selection of work from our designers & artists. Tag us to show us how you're using them! innovativegenomics.org/science-x-art/ 🧬🎨

Strategies for zygotic gene expression during plasmid establishment Conjugative plasmids are key drivers of horizontal gene transfer and the spread of antimicrobial resistance. Their successful establishment in new hos…

Rally nice review on plasmid leading strand anti defense and establishment @bursteinlab.bsky.social

www.sciencedirect.com/science/arti...

Precise virulence inactivation using a CRISPR-associated transposase for combating Enterobacteriaceae gut pathogens - Nature Biomedical Engineering A self-transmissible CRISPR-associated transposase system encodes a nanobody payload to treat Shiga toxin infections.

The Ronda lab's newest publication on targeted editing: www.nature.com/articles/s41...

IGI Investigator Carlotta Ronda's New Tool for Precision Microbiome Editing IGI Investigator Carlotta Ronda's New Tool for Precision Microbiome Editing - Innovative Genomics Institute (IGI)

Out now in Nature Biomedical Engineering from IGI's Carlotta Ronda @rondalab.bsky.social — a novel way to precisely edit the genomes of microbes in the microbiome to defeat harmful infections. Read more: ow.ly/efsS50WsVen

CRISPR researchers and startup entrepreneurs will share new building in UC Berkeley's Innovation Zone - Berkeley News A planned addition to the campus's Innovation Zone will expand lab space for the Innovative Genomics Institute and build out the largest innovation hub — Bakar Labs — at any U.S. university.

We’re thrilled to announce IGI–Bakar Labs. This new building will allow the IGI to continue expanding our impact in health and agricultural applications of #CRISPR, and will be shared with the Bakar Labs incubator for growing biotech companies. Learn more: news.berkeley.edu/2025/07/17/c...

CRISPR Researchers and Startup Entrepreneurs Will Share New Building in UC Berkeley's Innovation Zone CRISPR Researchers and Startup Entrepreneurs Will Share New Building in UC Berkeley's Innovation Zone - Innovative Genomics Institute (IGI)

Very excited to now share publicly that @innovativegenomics.bsky.social will be expanding to an amazing new building in the 2028 - 2029 academic year! innovativegenomics.org/news/igi-bak...

Our friends @thehesslab.bsky.social are actively looking for postdoctoral researchers interested in anerobic microbiology, and studying the rumen microbiome. #microbiologists #bioinformatics #microbiomes

Check out their website: hesslab.com

Thank you for the kind words! We agree there is still significant work to be done in this area, and many more model communities to potentially test. If it is any consolation we did choose PCC7120 as it is both in the genus Nostoc (NCBI taxonomy) and a genetic model for studying heterocyst formation.

The $20 Million Bet on CRISPR to Cure Rare Childhood Diseases The center will bring custom gene-editing treatments to children.

Out now in TIME — @jenniferdoudna.bsky.social on IGI's new initiative, teaming up with the @chanzuckerberg.bsky.social to create a new center for pediatric #CRISPR cures! Read here: ow.ly/E5un50WnbCi

graph of progress of various clinical, described in text at the link

Hot off the presses: our reader-friendly 2025 overview of #CRISPR clinical trials! 🧬 Check it out here: ow.ly/mRPl50WneTS

Click on the post for more info about the paper!!!

CRISPRi-ART enables functional genomics of diverse bacteriophages using RNA-binding dCas13d - Nature Microbiology Leveraging RNA-targeting dCas13d enables selective interference with phage protein translation and facilitates measurement of phage gene fitness at a transcriptome-wide scale.

Dive into our lab’s first peer-reviewed publication—co-led with our friends @benadler.bsky.social and Muntathar Al-Shimary from the @doudna lab! If you’ve already read the preprint, don’t miss the new updates: doi.org/10.1038/s415... @naturemicrobiol.bsky.social

🚨 Fresh from the press! We created and analyzed over 100 in vitro cyanobacterial consortia using well-characterized model cyanobacterial hosts to better understand how cyanobacteria recruit and interact with their microbiomes.

Check it out: doi.org/10.1093/isme...

Nostoc cyanobacteria by My Microscopic World

Out now from @diamondlab.bsky.social — stable microbiome communities using tractable cyanobacteria. An important development for folks working on cyanobacteria, microbial community formation and establishment in lab settings, and microbial community ecology! Read here: tinyurl.com/3cs2x6r7

🥳🥳 Our work exploring the core microbiomes of stable cyanobacterial communities is now out in the @isme-microbes.bsky.social Journal!!! Excellent work by @andrejakust.bsky.social and company!

#microbiology #cyanobacteria #metagenomics

4.6 Billion Years On, the Sun Is Having a Moment In the past two years, without much notice, solar power has begun to truly transform the world’s energy system.

Globally, roughly a third more power is being generated from the sun this spring than last. If this exponential rate of growth can continue, we will soon live in a very different world, @billmckibben.bsky.social writes.

We’re happy to share our preprint where applied phages to Microbiomes to test microbial interaction hypotheses - without losing the relevance of the community.

Bonus: using SNPs we studied how our targeted organism recovers from infection, and find how the community likely influences this process.

Unicore Enables Scalable and Accurate Phylogenetic Reconstruction with Structural Core Genes Abstract. The analysis of single-copy core genes, common to most members of a clade, is important for key tasks in biology including phylogenetic reconstru

Also if you want to construct phylogenetic trees across the tree of life, also brought to you by the FoldSeek team...Unicore

doi.org/10.1093/gbe/...

Multiple Protein Structure Alignment at Scale with FoldMason Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...

Some very nice multiple protein alignment software based on predicted structure brought to you by the folks behind #MMseqs and #FoldSeek ... Gotta try out FoldMason!!

www.biorxiv.org/content/10.1...

Universal rules govern plasmid copy number - Nature Communications Plasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-Martínez et al. analyse the copy number of thousands of diverse b...

Really fantastic paper on plasmid copy number control. Environmental plasmids are critical and surprisingly understudied tools for microbial community editing and manipulation

www.nature.com/articles/s41...

Scientists may have found a radical solution for making your hamburger less bad for the planet Scientists are studying how to genetically modify the makeup of cows’ gut microbiomes to prevent their planet-warming methane emissions.

Hello Bluesky! Our lab is very excited to be here. This is post is a little older but is a really lovely article by the @washingtonpost.com and @shannonosaka.bsky.social about some of the work we are doing on microbiomes to combat climate change!
www.washingtonpost.com/climate-solu...

#microbiome