@vpizzuti.bsky.social
IM PGY3 at University of Colorado, Future Heme/onc Hopeful, Former Engineer. He/him
I am happy to announce I was selected by @ash.hematology.org to receive the ASH HONORS Award!
Excited for this project studying PET/CT radiomics in DLBCL. Grateful to Dr. Manali Kamdar for her mentorship & ASH!
#ASHAwards #Fight4Hematology
@cudeptofmedicine.bsky.social
@cuhematology.bsky.social
@majorajay.bsky.social
18.12.2024 23:46 — 👍 1 🔁 0 💬 0 📌 0@cuhematology.bsky.social @cudeptofmedicine.bsky.social
18.12.2024 23:45 — 👍 0 🔁 0 💬 0 📌 0
Be on the lookout for a manuscript next year further describing our work! Big thanks to @ASH_hematology for allowing me to present and my mentor @majorajay for all the guidance and support!
Check out for more info:
- ashpublications.org/blood/article/…
- bison-pro.org
We plan to further expand this work by modeling pt cohorts at higher risk for inferior QoL outcomes, using the heatmap model to potentially detect those pts at risk for relapse/tx failure, and further examining the impact of novel txs in different disease states #ASH24 /9
18.12.2024 23:45 — 👍 1 🔁 0 💬 1 📌 0Taken together, this proof-of-principle study demonstrates we can successfully utilize the BISON-PRO study group to detect meaningful differences between groups of lymphoma pts receiving different treatments/monitoring #ASH24 /8
18.12.2024 23:45 — 👍 1 🔁 0 💬 1 📌 0
Similar improvements in reducing negative QoL outcomes were observed for active treatment groups at 6 months. Pts receiving cell therapies had temporary worsening of anxiety/depression early in tx but did have improvement in fatigue in our cohort #ASH24 /7
18.12.2024 23:45 — 👍 2 🔁 0 💬 1 📌 0
For the positive outcomes, surveillance pts saw minimal changes from 0 to 6 months. Pts receiving systemic tx or cell therapies had overall improved measures at 6 mos., but pts receiving chemo had worsened cognitive function at 6 months #ASH24 /6
18.12.2024 23:45 — 👍 1 🔁 0 💬 1 📌 0Once we observed these differences, we used these PROMIS T-scores to calculate percentiles and use the relative change in T-score percentiles from baseline to various time points to construct a heatmap model of positive and negative QoL measures #ASH24 /5
18.12.2024 23:45 — 👍 1 🔁 0 💬 1 📌 0
Similarly, PROMIS instruments were able to detect differences between groups, and here we highlight that global physical health and role functioning were higher in patients undergoing active surveillance vs active tx #ASH24 /4
18.12.2024 23:45 — 👍 2 🔁 0 💬 1 📌 0
Using FACT instruments, we observed significant differences between groups at baseline for lymphoma pts. Interestingly, QoL seemingly improved for pts with lymphoma undergoing active tx (FACT-LYM), but this was not seen with CLL pts (FACT-LEU) #ASH24 /3
18.12.2024 23:45 — 👍 2 🔁 0 💬 1 📌 0
In our initial feasibility study, we administered PROMIS and FACT instruments to patients in 3 arms longitudinally and sought to determine if we could detect meaningful differences between study groups #ASH24 /2
18.12.2024 23:45 — 👍 1 🔁 0 💬 1 📌 0
Interested in patient reported outcomes (PROs) in patients with lymphoma? Join me as I recap my poster highlighting our work on the BISON PRO QoL Study presented at #ASH24 #lymsm
18.12.2024 23:45 — 👍 7 🔁 1 💬 1 📌 1
Really grateful to have had the opportunity to present a poster highlighting my work with @majorajay.bsky.social at #ASH2024 it was a great experience with a great group of people!
10.12.2024 15:51 — 👍 9 🔁 1 💬 2 📌 1
Sneak peek of my mentee Dr. Pizzuti's heatmap PRO analysis PROs from our BISON-PRO Quality of Life Study (http://bison-pro.org). His abstract is at tonight's #ASH24 poster session; big congrats on his ASH Achievement Award! #MajorPROsASH cc @cuhematology.bsky.social @vpizzuti.bsky.social
09.12.2024 20:17 — 👍 7 🔁 1 💬 0 📌 0
