New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
10.09.2025 15:23 — 👍 7 🔁 3 💬 0 📌 0
Multi-panel figure showing that CTL function improves days after deletion of Cdc42.
. @adamrochussen.bsky.social, Claire Ma & Gillian Griffiths @griffithslab.bsky.social find that deletion of Cdc42 in primary T cells triggers transcriptional adaptation, leading to enhanced T cell function.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
11.08.2025 10:56 — 👍 5 🔁 2 💬 1 📌 0
Yup!
07.08.2025 00:48 — 👍 0 🔁 0 💬 0 📌 0
Excited to see this published today!
04.08.2025 19:46 — 👍 1 🔁 0 💬 0 📌 0
2025 | CSAR
Congrats to the other awardees. Very fortunate to be included in such a stellar group of young scientists. You can read about our projects here:
csar.org.uk/student-awar...
Thanks also to @cambridgeindy.bsky.social for highlighting the awards:
premium.cambridgeindependent.co.uk/business/tru...
21.07.2025 17:12 — 👍 0 🔁 0 💬 0 📌 0
Delighted to have been awarded a CSAR 2025 PhD Student Award for some of my work in the @griffithslab.bsky.social
@thecimr.bsky.social
The CSAR mission to recognise and prioritise research with real-world application is a super important one that I'll be taking forward as a postdoc & beyond
21.07.2025 17:12 — 👍 2 🔁 0 💬 1 📌 1
Welcome to the dynamic world of T cells!
08.01.2025 09:59 — 👍 6 🔁 1 💬 1 📌 1
Researcher at the CIMR, University of Cambridge @MarciniakLab interested in cell biology, especially proteostasis and the ER.
An interdisciplinary institute within University of Cambridge School of Clinical Medicine
Determining the molecular mechanisms of human disease, focusing on genetic/ pathogen-induced disruptions to fundamental cellular pathways
https://www.cimr.cam.ac.uk/
Final year medical student @uniofcam.bsky.social, biochemistry MSci in the Gershlick lab @thecimr.bsky.social. Interests include fluorescence microscopy, organelle dynamics & biophysics
Wellcome Trust career development fellow treating #IEI patients (athymia/SCID) @GreatOrmondSt & translational research @uclchildhealth to improve their outcomes!
https://profiles.ucl.ac.uk/70769-alexandra-kreins
EMBO postdoc fellow @jourdainlab.bsky.social at @dib-unil.bsky.social diving into the metabolism of cancer and immune cells | Previously @griffithslab.bsky.social @thecimr.bsky.social @Cambridge_Uni | City Coordinator of @pintofscience.ch
PhD student @griffithslab @Cambridge_Uni working on CAR-T cells 🧫
Discovering the remarkable intracellular dynamics of killer T cells
