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Centre for Medicines Discovery

@cmd.ox.ac.uk

A multi-disciplinary Institute within the University of Oxford which focuses upon translational activities to catalyse the discovery of new medicines.

55 Followers  |  22 Following  |  3 Posts  |  Joined: 27.11.2024  |  1.4641

Latest posts by cmd.ox.ac.uk on Bluesky

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🚀 On July 21, the Chemical Probes Portal celebrates 10 years! Launched after the landmark 2015 @NatChemBio paper by Arrowsmith et al., it now features >1150 compounds, >600 targets, and 1600+ expert reviews—powering better biomedical research. 🧪🔬
👉 chemicalprobes.org #ChemicalBiology @icr.ac.uk

21.07.2025 19:07 — 👍 8    🔁 5    💬 2    📌 1
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Cryo-EM studies by the Bullock group @cmd.ox.ac.uk reveal how phase II drug UM171 and cancer mutations similarly reshape E3 ligase KBTBD4 to recruit neosubstrate HDAC1/2. This unexpected structural mimicry may inspire future degrader discovery. #TPD #CancerBiology rdcu.be/egdFy

04.04.2025 13:22 — 👍 0    🔁 0    💬 0    📌 0
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AI-Powered Databases Boost the Alzheimer’s Drug Discovery Process Researchers studying Alzheimer’s disease are using artificial intelligence-powered databases to accelerate the drug discovery process by making it easier to sift through vast amounts of biomedical dat...

The ODDI has been featured in a Wall Street Journal article, describing the use of AI in identifying and stratifying novel targets for therapeutic intervention in Alzheimer’s disease.

www.wsj.com/articles/ai-...

01.04.2025 10:49 — 👍 2    🔁 0    💬 0    📌 0
Prof Daniel Ebner and Georgie Maynard in the lab

Prof Daniel Ebner and Georgie Maynard in the lab

Georgie Maynard and brother Charlie - LibDem MP for Witney, visited the Centre for Medicines Discovery, University of Oxford Brain Tumour Charity/CRUK funded research team led by Prof Daniel Ebner working on a five-year study to identify existing cancer drugs could shrink glioblastoma brain tumours.

31.03.2025 13:49 — 👍 0    🔁 0    💬 0    📌 0

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