Dimitris Vavylonis

Just posted (bioRxiv): A novel #mechanobiology model revealing how #immune #Tcells combine a #nucleus as a #piston, an #uropod, and #microenvironment to power #amoeboid #cellmigration in #cellconfinement via a hydraulic cell engine. #CellBiophysics #ImmuneMigration
www.biorxiv.org/content/10.1...

Thrilled to be featured in The New York Times! @nytimes.com

Fantastic piece by @jack-tamisiea.bsky.social on our discovery of the role of physical forces in evolution! With insightful comments from @wcratcliff.bsky.social!

There are a few more days to apply to the biophysics summer school in Crete! Deadline is extended to April 15.

Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required.
Please Repost 🙏 thanks !

Inside the Collapse at NIH Administration officials pressured NIH to avoid clear advice from the agency’s own lawyers to restart grant funding now.

The Atlantic story on the situation at NIH is sobering. We are so screwed.

www.theatlantic.com/health/archi...

🚨🚨Please repost!! 📢📢
Still time to submit short talk abstract for EindPBS2025!
Five themes this year:
• Mechanobiology
• Protein pattern formation
• 4D Genome
• Stochastic biology
• Biohydrodynamics
bit.ly/EdinPBS2025

🚨PA colleagues:

"Senator Fetterman wants to hear from you about how the federal funding freeze is affecting Pennsylvania."

"If your project has been impacted, please fill out our constituent impact form:" forms.office.com/g/mFv2JAPxpC

Get out your Other Support and share that info!

We are announcing the 2nd biophysics summer school in Rethymno, Crete, Greece for undergraduates, MS and PhD students. Please forward to anyone interested! biophysics.materials.uoc.gr
Lecturers include: Meredith Betterton, Michael Layden, Surya Maddu, Carl Modes, Tassos Pavlopoulos, Stas Shvartsman

From random gliding to ordered patterns.
The movie starts with microtubules gliding on a minus-end directed molecular motor.
Then, @bhagyanaths.bsky.social added a plus-end directed motor (magenta) to induce this polarity sorting and ordering process.
more details here:
www.pnas.org/doi/10.1073/...

YEARLY RECAP. Today we have the August 2024 issue of #CYTOSKELETON @cytoskeljournal.bsky.social. This #SpecialIssue on the #PHYSICS OF THE CYTOSKELETON was a huge hit when it came out! Loaded with #openaccess papers.Check it out here: onlinelibrary.wiley.com/toc/19493592... @dvavylonis.bsky.social

The NSF summer Research Experiences for Undergraduates (REU) program in Physics at Lehigh University invites student applications. We have faculty mentors in many areas, including biophysics and computational physics. Application deadline: Feb 3, 2025
physics.cas.lehigh.edu/undergraduat...

Flyer for the Biological Sciences PhD Program at Lehigh University, with images highlighting the diverse research being carried out in this program. Application deadline Jan 1st, 2025.

🚨The deadline to apply for Lehigh University’s Biological Sciences PhD program is just a few weeks away! Are you (or do you know) an amazing undergrad, post-bac, or master’s student passionate about science & ready to thrive in a supportive, interdisciplinary environment? Apply here!👉bit.ly/3VwZL29

Please join two sessions of the 8th Frontiers in Cytokinesis Subgroup on Sunday Dec 15 at #cellbio2024!

Do you want to learn more about RNA targeting to the midbody? Check out my student's Katie Vaeth talk in CellBio 2024 meeting in San Diego. She will talk in Cytokinesis session on December 15th, 5:00pm, room 29C.
plan.core-apps.com/ascbembo2024...

what a dynamic steady state! how does assembly match exactly the disassembly rate? how does it distribute in space without rupturing the cell in multiple pieces? fascinating movie!

For folks just arriving in #AcademicBsky or #ScienceBsky, here are a couple of Biophysics starter packs. Biophysicists, pls tag yourself and others and I will add you to the new starter packs. go.bsky.app/4AUjqVz

Couldn't find one so made a quick physics of life list, enjoy! go.bsky.app/EA2VsDN

Starting a theoretical biophysics starter pack, feel free to (self-) nominate, I’ll keep updating this in the next days/weeks!

go.bsky.app/RMF7jUK

I thought of a sneaky way to find my people on this thing.

Self-identify and I will add you...

See you at APS-DFD!

go.bsky.app/8Njfprh

Can you please add me? Thanks!

Can I join? Thanks!

Please add me. Thanks!

Can you please add me? Thanks! www.lehigh.edu/~div206/

Structural response of microtubule and actin cytoskeletons to direct intracellular load

rupress.org/jcb/article/...

Reconstitution of Arp2/3-nucleated actin assembly with proteins CP, V-1, and CARMIL Mooren et al. show that membrane-bound CARMIL activates capping protein (CP) by dissociating CP from V-1, thereby promoting actin polymerization nucleated by Arp2/3. The activity of CP is a critical d...

Reconstitution of Arp2/3-nucleated actin assembly with proteins CP, V-1, and CARMIL. Mooren, Olivia L. et al.
Current Biology, Volume 34, Issue 22, 5173 - 5186.e4
www.cell.com/current-biol...
Open access due to WashU agreement w/ Elsevier, fyi.