Molecular Epidemiology at LUMC

The MolEpi group congratulates Niels van den Berg with his Veni grant! 👏🥂

📝 Title of the project: Spousal survival Advantage by Marrying into longevity Enriched families (SAME)

👉 www.nwo.nl/en/news/200-...

#NWO #veni #grant #Causality #BDS-MOLEPI #LUMC #ODDISEI #DataScience #HealthCampustheHague

Translational genomics of osteoarthritis in 1,962,069 individuals Nature - A genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of...

Click on the link to this article: rdcu.be/erchW

🧬A landmark GWAS on osteoarthritis—the largest to date—was just published in Nature! As part of this global effort led by Helmholtz Munich, the Leiden team Ingrid Meulenbelt, Margo Tuerlings & Rick Mulders analyzed allelic expression imbalance in osteoarthritic cartilage and bone
#OAResearch #Molepi

Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants - GeroScience Human longevity, which is coupled to compression of age-related disease, is a heritable trait. However, only few common genetic variants have been linked to longevity, suggesting that rare, family-spe...

I am very proud to present you the first paper from the main research line of my group at the @mpiage.bsky.social in collaboration with my current group @molepi.bsky.social @bds-lumc.bsky.social at the LUMC, which is now published in @geroscience.bsky.social!

link.springer.com/article/10.1...

Tomorrow MolEpi's OA-PhD Student Giorgia Mazzini will be presenting "Human induced pluripotent stem cell-derived chondroprogenitors as a sustainable source for neo-cartilage production" @ the Tissue Engineering and Regenerative Medicine (TERMIS) in Freiburg (G). #oaresearch #molepi #bds #lumcleiden

German longevity study reveals novel rare pro-longevity alleles clustering in mTOR signaling pathway - GeroScience In this study, we investigated the contribution of rare coding variants to human longevity by analyzing whole exome sequencing data from 1245 German long-lived individuals (LLI) and 4105 geographicall...

Please check out this new publication by Daniel Kolbe from our ongoing collaboration between the @molepi.bsky.social @bds-lumc.bsky.social department at the Leiden University Medical Center and the IKMB at Kiel University!

link.springer.com/article/10.1...

We are looking for a postdoctoral researcher with bioinformatic expertise to join our research group @molepi.bsky.social @bds-lumc.bsky.social at the LUMC! More details, including the link to submit applications, are provided on the website below.

🖥️🧪

www.lumc.nl/en/about-lum...

Today Molepi's Margo Tuerlings will be pitching her research proposal "GROWTH – Determining the key determinants of human growth by elucidating chondrocyte cell states" for a @lumc_leiden funded PhD project. The pitching event will start at 12PM sharp! Zoom-link: us02web.zoom.us/j/4350642321...

Onze HLO stagiaires Daan en Justin zullen vanmiddag hun poster presenteren op de Leidse Hogeschool over hun artrose onderzoeksstage die ze doen bij de Moleculaire Epidemiologie! Komen jullie ff hallo zeggen?
@hogeschoolleiden.bsky.social @lumc.bsky.social

#HLO #lumc #molepi #artroseonderzoek