Shweta Shah

Clinical importance of prediction tools: 🔬
The prediction tool was developed with the data from 4000 people in multinational and multiracial cohorts and can be generalized to all.
Do you routinely use prediction tools with IgAN patients? #NephJC

Treatment in children: 👶💉
Management is based on RAS blockade, salt restriction, and blood pressure control. Glucocorticoids are used in those with persistent proteinuria or high-risk features, sometimes combined with cyclophosphamide in severe cases.

#NephJC

Off label use tried in small studies, awaiting Double PROTECT study

Noted

NephJC Shorts: MCD and FSGS Outcomes — NephJC A NephJC Shorts discussion of the long term data on kidney failure in FSGS and MCD

🤔 How often is end-stage kidney disease in patients with MCD/ FSGS? #NephSky #MedSky

@brianrifkin.bsky.social dissected the conclusions from the RaDar study in this #NephJCshorts

*the original article from @asnpublications.bsky.social

www.nephjc.com/news/nephjc-...

Everything said and done - although eGFR diff may signal ominous outcomes - practically speaking following one eGFR over time and seeing the eGFR fall predicts outcomes better than anything else ! And that’s what would be feasible across economies ! #NephJC

Introducing NephJC Shorts — NephJC In just over a decade of critical appraisal on NephJC, we have done several experiments. Some of them have worked out phenomenally well, such as the Freely Filtered podcast. Others were not ready for ...

The #NephJC editorial team knows that plenty of papers deserve attention between our bi-monthly, full-length discussions

✨Enter #NephJCShorts - quick hits with a critical eye 🦅 on high-impact reads
www.nephjc.com/news/nephjc-...

#MedSky #NephSky

“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”

From Rivka Galchen’s article in @newyorker.com:

“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”

And that’s how I’m going to explain it from now on.

Missed the #NephJC yesterday, but increasingly using Ritux for SDNS and even redosing at 6mo-1yr. Some stay in remission longer with add MmF

I do the same with any agent. Treat for 2 years then try off. If relapse, then another 2 years. #NephJc I don’t think there’s great data. Just seems a good balance of risk.

award winner list

Congrats to all the @asnkidney.bsky.social lifetime and mid-career awardees!

@ksusztak.bsky.social @genetickidneydoc.bsky.social @shinamenon.bsky.social @michellejtx.bsky.social and everyone else!

No, as someone who has used it before and now no longer using #NephJC

DDAvP will increase VWF levels but in an uremic mileu does it really help towards platelets adhesion?
#NephJC

Short window to work with!
#NephJC

Would make sense to check VWF otherwise hard to prove anything unless they compare with their previous institutional cohort
# NephJC

T0c
So how does DDAVP skip the bleeding drama? 🩸
🧬 Desmopressin → triggers cAMP → exocytosis of vWF & FVIII from endothelium
➡️ Boosts platelet adhesion in uremic dysfunction
⏱️ Onset: 30–90 min ⏳ Duration: 4–8 h
#NephJC

Due to cost and other logistics we stopped PFA, haven’t used desmo preemptively
#NePhJC

We used to do pre procedure DDAVP for abnormal PFA’s, mostly in CKD/ uremic kids
# NephJC

Peds Nephrologist @texaschildrens.bsky.social
No COI
#NephJC

Join hosts Emily Zangla and Jordy Salcedo with moderators from four nephrology sessions at the 2025 Pediatric Academic Societies Conference in Honolulu, Hawaii.
buff.ly/HdQWefG

Anyone seen membranous nephropathy( PLA2r neg) in pt with long standing Thal major, transfusion dependent?
#NephSky #askrenal @askrenal.bsky.social

🚨 The ASPN Scavenger Hunt is almost here!
🗓 Launches April 25 – are you ready?
✅ Download the ASPN Go App now
Complete tasks ➡ Win prizes!
🎁 Daily Yeti Cups + a grand prize Amazon Gift Card
#ASPNHunt #ComingSoon buff.ly/br6ocqR

Attending #PAS2025 ? Fun way to engage with fellow nephrons through our ASPN Go App!!📱📲
#pedsneph #ASPNHunt

@aspnr.bsky.social @nefronica-2rair.bsky.social @drm-sudha.bsky.social @sugarkro.bsky.social @asouth-neph.bsky.social

Skeleton Key Group Case #37: A case of elevated anion gap metabolic acidosis Welcome to the 37th case of the Skeleton Key Group, a team of nephrologists from around the world who build a periodic education package for the Renal Fellow Ne

Skeleton Key Group still going strong with their 37th electrolyte case

www.renalfellow.org/2025/03/19/s...

#NephMadness party ✅
Were there cookies? ❌
Was it a great discussion? ✅✅

Some were resistant, some needed incremental push, lot of disasters and conflicts, but finally convinced!!🤣🤣🤣

@nephmadness.bsky.social

Genetics in FSGS 🏆

After listening to this podcast, i might be a convert now!
Genetic counseling might be more important than sending genetic testing!!
@nephmadness.bsky.social #NephMadness

Love the science behind anti-nephrin Ab but
35% AA have one risk allele for APOL-1 & 14% have 2 risk alleles!

Those r huge number of people predisposed to AMKD!

IMO, it will be the winner , it has to🤣
@nephmadness.bsky.social

Are you a patient with Alport syndrome? The 2025 In-Person Alport Connect meeting will be in Chicago on July 19-20th. Child and teen programming available. See you there! alportsyndrome.org/for-patients...

On it! @nephmadness.bsky.social party Tuesday! Reading in process!! #NephMadness #NephSky

APOL1 versus Anti-nephrin!!

Loving it #NephMadness