S. García-Silva

Today is Worldwide Day against Melanoma. Do not forget a few easy-to-follow recommendations.

Dr. Patrick Hwu on X: "#ScienceSaturday ➡️ Melanoma secretes a protein called midkine (MDK), which plays a key role in reprogramming dendritic cells in the tumor microenvironment. ❓ How can this impact immune responses? ➡️ In this study by @msmelanoma et al., MDK was shown to induce immune https://t.co/mTkeNnoxKM" / X #ScienceSaturday ➡️ Melanoma secretes a protein called midkine (MDK), which plays a key role in reprogramming dendritic cells in the tumor microenvironment. ❓ How can this impact immune responses? ➡️ In this study by @msmelanoma et al., MDK was shown to induce immune https://t.co/mTkeNnoxKM

Nice comment on a fantastic paper by Xavi Catena, @msmelanoma.bsky.social and team.
x.com/PatrickHwuMD...

¿Curar el cáncer? Con la investigación empieza todo En el Centro Nacional de Investigaciones Oncológicas, el CNIO, investigamos para aprender a reducir el riesgo de cáncer; detectarlo cuanto antes; y tratarlo eficazmente. Sabemos que no es fácil, y que avanzaremos poco a poco. Pero tenemos claro que nuestro trabajo, la investigación, es el punto de partida para curar el cáncer. De todo esto […]

¿Cómo curar el cáncer? Lo primero, con investigación. Nuestros/as científicos/as os contarán del 27 al 29 de marzo cómo lo hacemos en @cniostopcancer.bsky.social . En nuestro stand en #MadridesCiencia (#IFEMA pabellón 1, stand 1E02), os  mostrarán:
👉🧵

https://surl.li/xvtxvh

#madrimasd

Exclusive: NIH to terminate hundreds of active research grants Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.

NEW: The NIH has begun terminating grants for active projects studying gender identity, DEI, environmental justice, climate change, among other topics.

At least 16 termination letters have already been sent — and hundreds more are coming, people inside NIH tell me.
www.nature.com/articles/d41...

Could multi-cancer tests help GPs spot cancer? - Cancer Research UK - Cancer News GPs see lots of people with cancer symptoms, but cancer cases can be like needles in the haystack. Multi-cancer tests might help find them.

Multi-cancer tests could signal to your GP if vague early-stage symptoms could be caused by cancer, potentially leading to earlier diagnosis when treatment is more likely to be successful.

Explore how these tests work and how they could support GPs to diagnose cancer earlier 👇

The spirit of multidisciplinary work in just one man, Wolfgang von Goethe. Here it is an illustration from Zur Farbenlehre (Theory of Colours).

Targeting ELOVL6 to disrupt c-MYC driven lipid metabolism in pancreatic cancer enhances chemosensitivity - Nature Communications Overexpression of c-MYC regulates tumor metabolism in pancreatic ductal adenocarcinoma (PDAC). Here the authors identify ELOVL6, a fatty acid elongase regulated by c-MYC, as a potential therapeutic ta...

1️⃣ We are super happy to announce our latest paper in Nature Communications! 🚀

We show how targeting ELOVL6 disrupts c-MYC-driven lipid metabolism in PDAC, enhancing chemosensitivity.

📄 Read more: doi.org/10.1038/s414...

#PDAC #CancerResearch #ELOVL6 🧪

Gracias JC!

The Spanish Association for Cancer Research, @aseica.bsky.social is now active in @bsky.app!!
Follow us for our actions in the defense of R&D, promotion of young investigators, women in science, basic-clinical interactions and innovación in and outside Spain.
More info in our digital magazine👇

Es una gran experiencia participar en #CONOCELAS de la @aseica.bsky.social y promover el dia de la mujer y la niña en la Ciencia. Gracias al #instituto_cardenal_cisneros, y gracias a #Rocio_Codes, #Jose_deJuan su directora #Mar_Ruiz_Calero y a los alumnos de 4º y 1ºESO y 1º de Bachillerato!

Promotional image for the Building Trust in Science 2025 conference

Join us on March 10th for the "Building Trust in Science for a More Informed Future" conference. The conference will span combatting disinformation, engaging the global public, and mobilizing knowledge for a better world: https://bit.ly/4aweGzL Cohosted with @aspeninstitute.bsky.social

La importancia de ALIA, la IA española de código abierto en el camino de la independencia tecnológica de EE. UU. y las grandes corporaciones España debe apostar por el desarrollo de sistemas de IA propios y en español, que permitan la independencia de Estados Unidos y las grandes corporaciones norteamericanas. ALIA es el primer paso en el ...

Ecosistema ALIA de LLMs enriquecidos en lenguas del estado:
- público, abierto y evaluable
- momento geopolítico
- implicaciones socio-económicas
- modelos pequeños (7B) y aplicaciones
- y el 40B en camino
@mintradigital.bsky.social SEDIA
@bsc-cns.bsky.social

theconversation.com/la-importanc...

Comprehensive Phenotyping of Extracellular Vesicles in Plasma of Healthy Humans – Insights Into Cellular Origin and Biological Variation Despite immense interest in biomarker applications of extracellular vesicles (EVs) from blood, our understanding of circulating EVs under physiological conditions in healthy humans remains limited. U....

Let's talk about circulating EV diversity and variation in healthy conditions!
doi.org/10.1002/jev2...

Fascinating study!

The VIDA COFUND Postdoctoral Programme is now open at @vhio.bsky.social . Please visit vhiovidaprogramme.eu for more info and join any of our #cancer #research laboratories in Barcelona! #oncosky #medsky 🧪 malumbreslab.org

Paralysed man flies virtual drone using brain implant Device that links neural signals to fine movements provides unprecedented control over speed and direction in a video-game obstacle course.

Researchers have developed a device that let a 69-year-old man with paralysis fly a virtual drone using only his thoughts.

https://go.nature.com/3E4es6Q

Thanks for posting this paper.

The Thorny Ethics of Planetary Engineering Whenever someone waxes poetic about terraforming alien worlds, it’s worth taking a moment to consider the ethical implications of the proposal.

“If there is life on Mars, I believe we should do nothing with Mars. The existence of an independent biology on a nearby planet is a treasure beyond assessing, and the preservation of that life must, I think, supersede any other possible use of Mars.”
–Carl Sagan, "Cosmos"

Vibrational fiber photometry: label-free and reporter-free minimally invasive Raman spectroscopy deep in the mouse brain - Nature Methods Vibrational fiber photometry enables Raman spectroscopy in the mouse brain with low impact, owing to the use of tapered fibers.

Vibrational fiber photometry, developed by the Pisanello lab, enables Raman spectroscopy in the mouse brain with low impact, owing to the use of tapered fibers.

www.nature.com/articles/s41...

Happy to share our last review on TAMs complexity! Mastered by @saraimrtnez.bsky.social & #janHochstadt from @cniostopcancer.bsky.social check it out: www.sciencedirect.com/science/arti...

Does Drinking Alcohol Cause Cancer? Learn About the Risks Learn more about the link between drinking alcohol and the risk of developing cancer.

Just for counteracting a little bit all the explicit publicity about drinking alcohol in any movie and TV series... Have a read on this. www.mskcc.org/news/does-dr...

Los médicos se preguntan por qué está aumentando el cáncer en las personas jóvenes Esta tendencia en menores de 50 años, acreditada por varios estudios –el último publicado en The Lancet Oncology– y confirmada en las consultas, mantiene en vilo a oncólogos y epidemiólogos, que apunt...

www.eldiario.es/sociedad/med...

Interesting article in Spanish regarding the increasing incidence of cancer in young adults. It's curious that we feel younger than the previous generations but we trend to prematurely suffer from old age-associated diseases.

🔴Would you like to work in one of Europe's leading research and technology centres❓

BSC offers you the opportunity to join a team of international scientific prestige & access to innovative facilities that will allow you to dream ✨

👀See our positions
➡ www.bsc.es/vacancies

#trabajo #feina #job

Top Cancer Research Advances at MSK in 2024 MSK researchers continued to make strides against cancer in 2024. Learn about some of their top discoveries.

In 2024, Researchers at MSK continued to make discoveries to advance the global understand of #cancer and develop new therapies.

Here's a look back at some of the most exciting scientific discoveries reported over the past year, in chronological order ⬇️

El @ciccancer.bsky.social contará con nuevo laboratorio especializado en la investigación de resistencia a tratamientos de cáncer que será dirigido por Mónica Álvarez Fernández se incorporará como investigadora principal

www.cicancer.org/science-soci...

Rectal Cancer Disappears After Experimental Use of Immunotherapy, Now an FDA Designated Breakthrough Therapy Rectal cancer patients saw their tumors disappear in a clinical trial involving immunotherapy at Memorial Sloan Kettering Cancer Center—without surgery, radiation, or chemotherapy.

A small but heralded clinical trial at MSK that saw #rectalcancer disappear in 100% of people who took part has taken a step towards approval by the @fda.gov.

Learn more about the clinical trial led by MSK's Dr. Andrea Cercek that is now an FDA Designated Breakthrough therapy. ⬇️

Jamie Goldfarb, a Stage IV melanoma survivor life was saved by a clinical trial treatment. At MRA, we're committed to funding innovative research & connecting patients with potentially life-saving clinical trials.
Visit curemelanoma.org/clinicaltrials to learn more about possible treatment options.

Use of Promotional Language in Grant Applications and Grant Success

"Levels of hype in successful NIH grant applications have increased over time"

Open Access
jamanetwork.com/journals/jam...