Innovative Genomics Institute

Jennifer Doudna is named 2026 Priestley Medalist The award recognizes the biochemist for discoveries on ribozyme function and CRISPR gene editing, and international science leadership

@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky 🧪

Tiny CRISPR Tool Opens the Door to Faster, Simpler Plant Genome Editing Tiny CRISPR Tool Opens the Door to Faster, Simpler Plant Genome Editing - Innovative Genomics Institute (IGI)

In a recent paper, IGI's @jenniferdoudna.bsky.social @doudna-lab.bsky.social and Jill Banfield @banfieldlab.bsky.social collaborate with UCLA's @jacobsenucla.bsky.social to create a new, tiny #CRISPR tool for quicker, easier plant genome editing! Read more in this Q&A with Steve: ow.ly/6Szs50VGElf

illustration shows poppies that are clear or fuzzy to illustrate preventing versus treating disease or enhancing a trait

Did you know that the illustrations in our resources like CRISPRpedia are free to use for non-commercial, educational purposes? Check out our #SciArt page to see a selection of the amazing work from our designers and artists. Tag us to show us how you're using them! lnkd.in/e_CGXPAz

Untangling phage immunity systems can be really challenging but @owentuck.bsky.social and team used phylogeny and biochemistry beautifully to show how a pair of genes got repurposed as a component in multiple defence systems.

7 world-changing UC innovations that emerged from federal research funding From the internet to the ozone layer, AI to the human genome, UC scientists have turned federal research funding into history-making, economy-boosting solutions.

🧬 25 years ago, UC Santa Cruz posted the Human Genome Project’s first draft of the human genome sequence online, available to anybody for free. Scientists and doctors around the world have since used this data to accelerate diagnosis and treatment. Via @uofcalifornia.bsky.social: bit.ly/4eV96cm

CRISPR Made Simple CRISPR Made Simple - Innovative Genomics Institute (IGI)

We ❤️ phages and this illustration from our resource CRISPR Made Simple: innovativegenomics.org/crispr-made-...

Drop a bad guy you actually love.

Science x Art Science x Art - Innovative Genomics Institute (IGI)

Did you know that the illustrations in our resources like CRISPRpedia are free to use for non-commercial, educational purposes? Check out our Science x Art page to see a selection of work from our designers & artists. Tag us to show us how you're using them! innovativegenomics.org/science-x-art/ 🧬🎨

Precise virulence inactivation using a CRISPR-associated transposase for combating Enterobacteriaceae gut pathogens - Nature Biomedical Engineering A self-transmissible CRISPR-associated transposase system encodes a nanobody payload to treat Shiga toxin infections.

The Ronda lab's newest publication on targeted editing: www.nature.com/articles/s41...

Meet the Ronda lab members!

IGI Investigator Carlotta Ronda's New Tool for Precision Microbiome Editing IGI Investigator Carlotta Ronda's New Tool for Precision Microbiome Editing - Innovative Genomics Institute (IGI)

Out now in Nature Biomedical Engineering from IGI's Carlotta Ronda @rondalab.bsky.social — a novel way to precisely edit the genomes of microbes in the microbiome to defeat harmful infections. Read more: ow.ly/efsS50WsVen

Jennifer Doudna is helping drive the effort to make personalized CRISPR cures for children a reality.

@innovativegenomics.bsky.social

bit.ly/4nDufvI

CRISPR researchers and startup entrepreneurs will share new building in UC Berkeley's Innovation Zone - Berkeley News A planned addition to the campus's Innovation Zone will expand lab space for the Innovative Genomics Institute and build out the largest innovation hub — Bakar Labs — at any U.S. university.

We’re thrilled to announce IGI–Bakar Labs. This new building will allow the IGI to continue expanding our impact in health and agricultural applications of #CRISPR, and will be shared with the Bakar Labs incubator for growing biotech companies. Learn more: news.berkeley.edu/2025/07/17/c...

Out today in @natbiotech.nature.com, IGI's @urnov.bsky.social and leaders across the #biotech industry on expanding patient access to #CRISPR cures with platform technology.

The $20 Million Bet on CRISPR to Cure Rare Childhood Diseases The center will bring custom gene-editing treatments to children.

More on the new Center
time.com/7300257/cent...

🥳🥳 Our work exploring the core microbiomes of stable cyanobacterial communities is now out in the @isme-microbes.bsky.social Journal!!! Excellent work by @andrejakust.bsky.social and company!

#microbiology #cyanobacteria #metagenomics

Nostoc cyanobacteria by My Microscopic World

Out now from @diamondlab.bsky.social — stable microbiome communities using tractable cyanobacteria. An important development for folks working on cyanobacteria, microbial community formation and establishment in lab settings, and microbial community ecology! Read here: tinyurl.com/3cs2x6r7

graph of progress of various clinical, described in text at the link

Hot off the presses: our reader-friendly 2025 overview of #CRISPR clinical trials! 🧬 Check it out here: ow.ly/mRPl50WneTS

The $20 Million Bet on CRISPR to Cure Rare Childhood Diseases The center will bring custom gene-editing treatments to children.

Out now in TIME — @jenniferdoudna.bsky.social on IGI's new initiative, teaming up with the @chanzuckerberg.bsky.social to create a new center for pediatric #CRISPR cures! Read here: ow.ly/E5un50WnbCi

Our conversation photo and photo of Baby KKJ

A new Pediatric Center for CRISPR Cures builds on the recent saved life of Baby KJ, who expeditiously had bespoke in vivo base genome editing
@jenniferdoudna.bsky.social @doudna-lab.bsky.social
@innovativegenomics.bsky.social
@chanzuckerberg.bsky.social
erictopol.substack.com/p/new-center...

Aysel Ogul, an undergraduate research assistant at the IGI, pipetting in the lab with her mentor Kevin Briseno

We're excited to announce that the IGI is teaming up with @chanzuckerberg.bsky.social to create a new center for pediatric #CRISPR cures @UCSF + @ucberkeleyofficial.bsky.social building on the recent success of an on-demand CRISPR therapy for Baby KJ. Read more: ow.ly/XUQH50Wmt7U

Kevin Wasko (left) and Honglue Shi in front of their gel imager, confirming that the SpRY Cas9 variant struggles to effectively open DNA

“What we’ve done here is uncover the secret sauce that makes typical #Cas9 — the original Nobel molecule — so efficient and precise." – Co-first author Honglue Shi of the @doudna-lab.bsky.social on his recent paper in Molecular Cell

Read here: innovativegenomics.org/uncovering-c...

Photo: Members of the SambaFunk! collective dance and drum during the 2019 Berkeley Juneteenth Festival (Liliana Michelena/KQED). Catch them performing at noon this Sunday!

In celebration of Juneteenth, the 38th annual Berkeley Juneteenth Festival will be held this Sunday in South Berkeley! Check out activities for the whole family including the KID/STEM zone! Learn more here: berkeleyjuneteenth.org

#Juneteenth #BlackInSTEM

Photo: SambaFunk! in 2019 in Berkeley/KQED

Baby KJ looking alert and healthy

Thanks to the BBC's The Inquiry program for great conversations with IGI's @jenniferdoudna.bsky.social @doudna-lab.bsky.social and @urnov.bsky.social about Baby KJ, #CRISPR on-demand, and the future of personalized medicine!

Listen here: www.bbc.com/audio/play/w...

Photo credit: TODAY

Happy #Pride!
Love, Rubisco

Baby KJ’s Bespoke Gene Therapy Is a Masterclass in Scientific Collaboration Scientists behind a world-first gene therapy reveal how they teamed up with experts across academia and industry to produce a drug from start to finish in just six months.

From The Scientist - How collaboration lead to KJ's on-demand #CRISPR treatment

Read more: ow.ly/shuz50W7nIL

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YouTube video by U.S. Food and Drug Administration FDA Roundtable on Cell and Gene Therapy

More here: www.youtube.com/watch?v=0qDh...

YouTube video by U.S. Food and Drug Administration FDA Roundtable on Cell and Gene Therapy

IGI's @urnov.bsky.social today at the #FDA Roundtable on Cell & Gene Therapy. Grateful for an opportunity to share more about using #CRISPR on demand to treat rare diseases!

Watch here: www.youtube.com/watch?v=0qDh...

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Here: Baby KJ at home with his mom Nicole.
This really happened, folks. Hundreds of people from 8 organizations (led by Rebecca Ahrens-nicklas and Kiran Musunuru) came together to make a bespoke gene editor for this kiddo. He was once in the 7th percentile of body weight. Look at him now! ❤️

CRISPRpedia: Chapter 5 CRISPR & Ethics

Check out CRISPRpedia, our resource on all things #CRISPR! The latest chapter is on CRISPR & ethics: innovativegenomics.org/crisprpedia/...

CRISPRpedia features 85+ original illustrations that are free to download & use for non-commercial purposes!

#STEMeducation #STEMed #bioethics #SciArt