Linda Crnic Institute for Down Syndrome

As Down Syndrome Awareness Month comes to a close, the Crnic Institute would like to thank the 1,400+ participants in the Human Trisome Project! Thank you to all our participants for being the research heroes who make our work possible. Learn more about the HTP at trisome.org.

This #DownSyndromeAwarenessMonth, we celebrate the incredible self-advocates among our staff at the Crnic Institute: Grace and Andrew. Join us in recognizing their extraordinary contributions and the impact people with Down syndrome bring to the world, today and every day! 💙💛 @cuanschutz.bsky.social

Crnic Institute Team

Crnic Institute Team

Crnic Institute Team

Crnic Institute Team

Our team had an amazing time at this year's Be Beautiful Be Yourself Fashion Show, hosted by the Global Down Syndrome Foundation! Thank you to all who made this year's event a success. Our work would not be possible without you!

HTP Participant

¿Asistirás a la Reunión Familiar 2025 de la Black Down Syndrome Association? ¡Podrás participar en el Proyecto del Trisoma Humano en persona durante este evento! Más información en bit.ly/Trisome-es.

NEW RESEARCH PARTICIPATION OPPORTUNITY! CONTACT OUR TEAM! ENROLLING NOW THROUGH 2028 Project CAPE-abilities C o m m u n i c a t i o n A n d P l a y E a r l y a b i l i t i e s i n D o w n S y n d r o m e The DD Lab at CSU has a new research study that focuses on how young children with Down syndrome play and communicate! Play and communication are important for a child’s development. This study will show how these skills grow in children with Down syndrome and how they connect to other health conditions and autism. We are excited to learn more about your child’s CAPE-abilities! Infants with Down syndrome birth to 24 months Locations throughout the US Families can receive up to $300 Study Lead: Deborah Fidler, Ph.D. at CSU 970-680-3415 ddlabcsu@gmail.com | DEVELOPMENTAL DISABILITIES RESEARCH LABORATORY #40456920.0 IRB Approved at the Study Level Apr 25, 2024

The Developmental Disabilities Lab at CSU Announces a NEW Research Opportunity! For more information, call or email the research team at 970-680-3415 or ddlabcsu@gmail.com.

We’re working with Boys Town National Research Hospital from November 7-12 in Dallas, TX to better understand hearing and balance in people with Down syndrome. Compensation is provided. Learn more and schedule at bit.ly/HearinginDS, or email dsresearch@cuanschutz.edu.

Text: Celebrating Down Syndrome Awareness Month Linda Crnic Institute for Down Syndrome Image: five photos of people with Down syndrome

October is Down Syndrome Awareness Month! We invite you to join us in raising awareness and celebrating our research heroes. Together, we can continue advancing science that makes a lasting difference.

#DownSyndromeAwarenessMonth @cuanschutz.bsky.social

HTP Participant

¿Asistirás a la Reunión Familiar 2025 de la Black Down Syndrome Association? ¡Podrás participar en el Proyecto del Trisoma Humano en persona durante este evento! Más información en bit.ly/Trisome-es.

HTP Participant

Are you attending the 2025 Black Down Syndrome Association Family Reunion? Help the Global Down Syndrome Foundation and Crnic Institute researchers learn more about the health of people with Down syndrome! You can participate in the Human Trisome Project in-person at this event! 🔗 bit.ly/Trisome.

Crnic Institute Supergroup October 15, 2025 from 11:30 a.m. - 1 p.m. Jamie Belkind-Gerson, MD, MSc Director of Neurogastroenterology Children’s Hospital Colorado Professor of Pediatrics CU Anschutz Division of Gastroenterology Enteric Nervous System Lab Presentation: Gastrointestinal motility disorders in Down syndrome Marisa Stahl, MD, MSCS Assistant Professor of Pediatrics CU Anschutz Division of Gastroenterology Colorado Center for Celiac Disease Presentation: Genetic Risk Profile of Celiac Disease in Down Syndrome

Join us this Wednesday, October 15, for our monthly Supergroup presentations! This event is open to all Crnic Institute Members. Become a member today at bit.ly/CrnicInstituteMember. The location and Zoom link for this event will be shared on a calendar invite with our members.

Birthday study flyer

CSU Announces a NEW Research Opportunity! The DD Lab is studying the fascinating connection between biology and learning in infants with Down syndrome. For more information, call or email the research team at (970) 680-3415 or ddlabcsu@gmail.com.

The Linda Crnic Institute for Down Syndrome needs people with Down syndrome ages 25-55 to join a community of potential clinical trial volunteers who could help one day find a cure for Alzheimer’s disease. Visit trcds.org for more information.

Our team had an amazing time meeting with our community at the Northern Colorado Down Syndrome Association Buddy Walk! Thank you to all who showed up and stopped by our booth. Make sure to get DS-Connected today at ds-connect.org

Congratulations to Lauren Dunn, PhD, for successfully defending her thesis, entitled "Altered hepatic metabolism in Down syndrome." We look forward to seeing what Dr. Dunn accomplishes in the field of Down syndrome research.

Our new research opportunity aims to better treat chronic constipation in individuals with Down syndrome and improve future care. Be a part of the movement towards a healthier, happier future. Tag someone who might be interested! https://bit.ly/3tICP5p

Text: 6th International Conference T21RS Research Society Denver, CO June 17-20

Save the Date! The 6th International Conference of the Trisomy 21 Research Society will be held June 17–20, 2026, in Denver, Colorado. Stay updated at bit.ly/3WguBf7.

NEW RESEARCH PARTICIPATION OPPORTUNITY! CONTACT OUR TEAM! ENROLLING NOW THROUGH 2028 Project CAPE-abilities C o m m u n i c a t i o n A n d P l a y E a r l y a b i l i t i e s i n D o w n S y n d r o m e The DD Lab at CSU has a new research study that focuses on how young children with Down syndrome play and communicate! Play and communication are important for a child’s development. This study will show how these skills grow in children with Down syndrome and how they connect to other health conditions and autism. We are excited to learn more about your child’s CAPE-abilities! Infants with Down syndrome birth to 24 months Locations throughout the US Families can receive up to $300 Study Lead: Deborah Fidler, Ph.D. at CSU 970-680-3415 ddlabcsu@gmail.com | DEVELOPMENTAL DISABILITIES RESEARCH LABORATORY #40456920.0 IRB Approved at the Study Level Apr 25, 2024

The Developmental Disabilities Lab at CSU Announces a NEW Research Opportunity! For more information, call or email the research team at 970-680-3415 or ddlabcsu@gmail.com.

Text: Linda Crnic Institute for Down Syndrome New Grant Awarded: Deirdre Logsdon, PhD, "Defining the association between trisomy 21 and placentation defects" Headshot of Deirdre Logsdon, PhD

Congratulations to Dr. Deirdre Logsdon of the CU Boulder BioFrontiers Institute for receiving an NIH R21 grant for her project, entitled "Defining the association between trisomy 21 and placentation defects." We look forward to seeing these exciting discoveries!

@cumedicalschool.bsky.social @cuanschutz.bsky.social

Doctor and person with Down syndrome

New research from the Crnic Institute reveals how trisomy 21 shapes biology across the lifespan, providing new insight into how Down syndrome affects health from childhood through adulthood and highlights opportunities for age-specific interventions. Learn more at bit.ly/48vXP0X.

is your little one turning one? Join the birthday study! The DD Lab at CSU is studying the fascinating connections between early learning and biology in babies with Down syndrome! PAID RESEARCH STUDY UP TO $300 FLEXIBLE AND CONVENIENT Children younger than 13 months with Down syndrome Contact our team! DEVELOPMENTAL DISABILITIES RESEARCH LABORATORY (970)680-3415 | ddlabcsu@gmail.com Study Lead: Deborah Fidler, Ph.D. at CSU

CSU Announces a NEW Research Opportunity! The DD Lab is studying the fascinating connection between biology and learning in infants with Down syndrome. For more information, call or email the research team at (970) 680-3415 or ddlabcsu@gmail.com.

Aurélie Ledreux, PhD, and Juan Fortea, MD, PhD

Congratulations to Dr. Aurélie Ledreux and Dr. Juan Fortea on a new publication! Read "Cargo of small extracellular vesicles from neuronal origin shows progression of dementia in individuals with Down syndrome" at https://bit.ly/4gGoFWk

Scientists and physicians from the Crnic Institute at the University of Colorado, Children’s Hospital Colorado, and Children’s Hospital Los Angeles have teamed up to investigate potential treatments for Down Syndrome Regression Disorder (DSRD). Visit https://bit.ly/3tjKC98 to learn more.

"Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse model," published in iScience, a Cell Press Journal

Congratulations to Dr. Paula Arya, Dr. Joaquin Espinosa and Dr. Kelly Sullivan for leading a new study published in iScience entitled "Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse model." Read more at https://bit.ly/3Io31cK.

Our DS-Connect team had an amazing time at the NYC Buddy Walk earlier this month, hosted by the National Down Syndrome Society! Make sure to get DS-Connected today at ds-connect.org

Postdoc Appreciation Week Brian Niemeyer, PhD Sara Sherman, PhD Ariel Timkovich, PhD

As Postdoc Appreciation Week ends, we celebrate our three outstanding postdocs at the Crnic Institute. Thank you, Dr. Brian Niemeyer, Dr. Sara Sherman and Dr. Ariel Timkovich, for your invaluable contributions. Our mission to advance Down syndrome research wouldn’t be possible without you!

Are you attending the DSDN Rockin' Moms Retreat? Visit the DS-Connect booth to learn how DS-Connect helps families and individuals with Down syndrome participate in research, access valuable resources and find the latest community events. Come by and get DS-Connected TODAY! ds-connect.org

Super excited to attend the 54th @isehsociety.bsky.social
conference in Japan next week! First time in Japan. First time at a hematology conference. Great chance to network with the world's best and share our CH work in Down Syndrome.
@crnicinstitute.bsky.social @cuanschutz.bsky.social

The Linda Crnic Institute for Down Syndrome needs people with Down syndrome ages 25-55 to join a community of potential clinical trial volunteers who could help one day find a cure for Alzheimer’s disease. Visit trcds.org for more information.

Our new research opportunity aims to better treat chronic constipation in individuals with Down syndrome and improve future care. Be a part of the movement towards a healthier, happier future. Tag someone who might be interested! https://bit.ly/3tICP5p