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Leonardo Claudino

@lmbclaudino.bsky.social

Computer Science PhD. Staff Scientist at the Laboratory of Brain and Cognition (LBC) @NIMH/NIH. Opinions are my own.

109 Followers  |  229 Following  |  25 Posts  |  Joined: 13.11.2024  |  2.3116

Latest posts by lmbclaudino.bsky.social on Bluesky

This is a nice paper. It faces down a common problem: in order to explain to why a common approach cannot work even in theory, we first need to teach a framework in which regression is not magic that tells us which variables on right cause the variable on left. It's exhausting.

Anyway great paper!

07.10.2025 11:38 β€” πŸ‘ 79    πŸ” 15    πŸ’¬ 3    πŸ“Œ 0

Mirror manifolds: partially overlapping neural subspaces for speaking and listening https://www.biorxiv.org/content/10.1101/2025.09.20.677504v1

20.09.2025 23:15 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

In retrospect, it was the presidency of Obrack Ofuane -- a Greek ambulance-chasing lawyer from Queens with eye-popping white veneers -- from 2009 to 1017 that set us on this current course toward madness

08.08.2025 19:21 β€” πŸ‘ 99    πŸ” 16    πŸ’¬ 3    πŸ“Œ 0

Repetition-related reductions in neural activity support improved behavior through increases in oscillatory power https://www.biorxiv.org/content/10.1101/2025.07.06.663291v1

07.07.2025 03:17 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 2

New work from our lab investigating the relationship between repetition suppression, repetition priming and increases in oscillatory power in simultaneous fMRI-EEG. Induced power increases are strongly associated with priming magnitude, supporting a mix of the synchrony and facilitation models.

07.07.2025 14:30 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
This is figure 1, which shows aniline synthesis from carboxylic acids in vitro and in vivo.

This is figure 1, which shows aniline synthesis from carboxylic acids in vitro and in vivo.

Escherichia coli bacteria (E. coli) can convert a molecule derived from a waste plastic bottle into paracetamol, a pain medication also known as acetaminophen, according to a paper in Nature Chemistry. go.nature.com/44cvLw1 #chemsky πŸ§ͺ

06.07.2025 01:16 β€” πŸ‘ 37    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1
Wikipedia definition of "idiot plot": In literary criticism, an idiot plot is one which is "kept in motion solely by virtue of the fact that everybody involved is an idiot",[1]:β€Š26β€Š and where the story would quickly end, or possibly not even happen, if this were not the case.

Wikipedia definition of "idiot plot": In literary criticism, an idiot plot is one which is "kept in motion solely by virtue of the fact that everybody involved is an idiot",[1]:β€Š26β€Š and where the story would quickly end, or possibly not even happen, if this were not the case.

06.06.2025 00:42 β€” πŸ‘ 9854    πŸ” 1855    πŸ’¬ 113    πŸ“Œ 152
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Computational characterization of metacognitive ability in subjective decision-making Metacognition is the process of reflecting on and controlling one's own thoughts and behaviors. Metacognitive ability is often measured through modeling the relationship between confidence reports and...

Preprint alert 🚨! Excited to share our new work on metacognition in value-based decision-making. www.biorxiv.org/cgi/content/.... We ask whether it is possible to derive a computational measure of metacognitive ability for economic preference choices.

29.05.2025 02:41 β€” πŸ‘ 25    πŸ” 13    πŸ’¬ 1    πŸ“Œ 1

This project began after my move to NIH and has been an eye-opening synthesis of my and Silvia's previous work. Couldn't be prouder of the incredible work of my first trainee and first author Corey Plate, who has just left NIH to begin his MD/PhD!

29.05.2025 03:10 β€” πŸ‘ 14    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Here’s your chance to ask the new NIH director some questions. Don’t be shy!

25.04.2025 02:58 β€” πŸ‘ 19    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
Meme shows a pentagon with the word β€˜pentagon’ underneath. Next is a hexagon with hexagon written underneath, then an octagon with octagon written underneath. The final shape looks like a crashing stock market outline with β€˜Portfoliogone’ written underneath

Meme shows a pentagon with the word β€˜pentagon’ underneath. Next is a hexagon with hexagon written underneath, then an octagon with octagon written underneath. The final shape looks like a crashing stock market outline with β€˜Portfoliogone’ written underneath

I’ll just leave this here.

06.04.2025 15:23 β€” πŸ‘ 107    πŸ” 17    πŸ’¬ 3    πŸ“Œ 0
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Majority of Brazil's Supreme Court panel accepts coup charge against ex-President Bolsonaro A majority of a panel of justices of Brazil’s Supreme Court has accepted charges against former President Jair Bolsonaro over an alleged attempt to stay in office after his 2022 election defeat.

A majority of a panel of justices of Brazil’s Supreme Court has accepted charges against former President Jair Bolsonaro over an alleged attempt to stay in office after his 2022 election defeat.

26.03.2025 15:39 β€” πŸ‘ 451    πŸ” 89    πŸ’¬ 23    πŸ“Œ 37
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Temporal fMRI Dynamics Map Dopamine Physiology Spatial variations in dopamine function are linked to cognition and substance use disorders but are challenging to characterize with current methods. Because dopamine influences blood vessel dilation,...

Interested in dopamine? Have fMRI data? We’ve identified a temporal BOLD feature that carries rich information about dopamine physiology. This measure, obtainable from resting-state and task fMRI, opens new ways to indirectly probe dopamine’s role in cognition and disease. 1/n tinyurl.com/bddyz67b

26.03.2025 12:40 β€” πŸ‘ 99    πŸ” 43    πŸ’¬ 5    πŸ“Œ 1

We still have space for a few more folks to attend. All expenses paid!

26.03.2025 13:37 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1

Can’t wait!!

20.03.2025 21:00 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This cure for sickle cell anemia was made possible by NIH-funded research to turn the gene for fetal hemoglobin back on. It was done predominantly by NIH researchers, including intramural researchers on the NIH campus.

irp.nih.gov/catalyst/33/...

15.03.2025 18:44 β€” πŸ‘ 1187    πŸ” 480    πŸ’¬ 11    πŸ“Œ 13

as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech
bsky.app/profile/need...

15.03.2025 18:49 β€” πŸ‘ 329    πŸ” 116    πŸ’¬ 3    πŸ“Œ 0

Indeed, this expect evidence from denialists is a different thing, and would be too passive aggressive under current circumstances. I’m with you that the press has to put these guys on the spot as much as possible to break there fallacies.

11.03.2025 21:07 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

In science, when someone states there is a link, it normally comes with some kind of evidence, so it is reasonable that the interviewer expected it without having to ask (didn’t read it either)

11.03.2025 18:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Drinking this much coffee a day is linked to a lower risk of several diseases People who consumed 200 to 300 milligrams of caffeine a day were less likely to develop coronary heart disease, Type 2 diabetes or stroke.

People who consumed 200 to 300 milligrams of caffeine a day were less likely to develop coronary heart disease, Type 2 diabetes or stroke.

11.03.2025 12:00 β€” πŸ‘ 112    πŸ” 17    πŸ’¬ 17    πŸ“Œ 32
Post image

Can we use brain scans to identify biologically distinct "autisms"? And If so, how?

In our latest cross-species study πŸ­πŸ‘¨ with @iitalk.bsky.social we dive into these questions!

Find out more here πŸ‘‡πŸ‘‡
www.biorxiv.org/content/10.1...

Thread below 🧡 1/n

06.03.2025 11:18 β€” πŸ‘ 74    πŸ” 27    πŸ’¬ 5    πŸ“Œ 3

β€œWaste, abuse and fraud” is the new bs talking point to be repeated over and over without any evidence by the red hat folks

06.03.2025 18:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Let me ask my kids when I get home. They can come up with something much better than I could ever

05.03.2025 22:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

He already deserves a name

05.03.2025 22:49 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

He knows he is never going to be held accountable for what he does, let alone what he says.

05.03.2025 04:02 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It’s everywhere, at every news station, with no fact checking at all. And I just can’t stand Mike Johnson’s face.

05.03.2025 02:57 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Could be. The question is, where is the fact checking on this? Is there anywhere we can see pictures of database tables, records, etc? Otherwise this doesn’t mean anything.

05.03.2025 02:52 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Are these fraud claims anywhere they can be fact checked or is he just pulling them out of his maga hat?

05.03.2025 02:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
A still from β€œI’m Still Here.”

A still from β€œI’m Still Here.”

β€œI’m Still Here” wins Best International Feature Film at the #Oscars. It will also be up for Best Picture at the end of the night, and its star, Fernanda Torres, remains a dark horse in the Best Actress category. www.newyorker.com/live/oscars-...

03.03.2025 03:13 β€” πŸ‘ 205    πŸ” 17    πŸ’¬ 5    πŸ“Œ 4

I believe there is no coming back from season 2. It’s so bad that Misty is the most likable of the girls in both timelines. Shauna and Tai are despicable. Van is a nothing. And Travis?

03.03.2025 04:53 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

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