Christopher Chong

CD14-deficiency protects against osteoarthritic subchondral bone sclerosis via enhanced osteoclastogenesis following joint injury https://www.biorxiv.org/content/10.64898/2026.02.10.705094v1

📍Radio Eltham

Australia politics live: Liberals face ‘existential crisis’, Jane Hume says; Israeli president arrives in Sydney Follow live

"New survey data from the Health Students Alliance found 42% of health students are going hungry during placements."

www.theguardian.com/australia-ne...

Synovial Fluid Cell Counts and the Degree of Synovial Tissue Lymphocytic Inflammation in Patients with Rheumatoid Arthritis. Graphical abstract created using BioRender

Analysis of synovial fluid and tissue samples from rheumatoid arthritis patients undergoing knee arthroplasty showed synovial fluid features reflected findings in the synovial tissue, and could differentiate high & low lymphocytic synovial inflammation

ACR Open Rheumatology
doi.org/10.1002/acr2...

Daily activity patterns may predict mortality in knee osteoarthritis Individuals with knee osteoarthritis who had low activity levels in the morning and evening demonstrated a two-fold higher risk for earlier mortality than other patients, according to data published i...

Daily activity patterns may predict mortality in knee osteoarthritis
www.healio.com/news/rheumat...

Footscray, Victoria, Australia

⚫🟡🔴 Our Survival Day 2026 @ The Briars, Mt Martha, Victoria, Australia 🔵🟢⚪

Sankey diagram demonstrating the transition of phenotypes before and after total joint arthroplasty

Psychological distress phenotypes were used to model changes between pre- and post-op experiences of 494 patients who underwent primary hip or knee arthroplasty at a university health system

ACR Open Rheumatology
doi.org/10.1002/acr2...

(1/2) This 76 y/o male presented with complaints of muscle pain. Their past medical history is significant for Sjogren’s syndrome, fibromyalgia, peripheral neuropathy, hypertension and hyperlipidemia. Laboratory studies showed normal CPK and elevated CRP.

#neuropathology #neuromuscular #pathsky

Rheumatology Around the World 🌎

Challenges of Assessment of SpondyloArthritis international Society Criteria in Real-World Colombian Patients With Spondyloarthritis: A Cross-Sectional Study

📖 doi.org/10.3899/jrhe...

#AxialSpondyloarthritis #CohortStudies #Colombia #Spondylarthritis

Image of an animal cell showcases web-like fibers called vimentin — a protein that provides mechanical stability to cells and tissues

Created using fluorescence microscopy, this stunning image of an animal cell showcases thin, web-like fibers called vimentin — a protein that provides mechanical stability to cells and tissues, despite a single vimentin being ~7000x smaller than the width of a human hair. 📸 @aaandmoore.bsky.social

Racism in healthcare is a serious barrier that prevents Indigenous peoples from receiving the care they need. At @usask.ca, Dr Holly Graham is supporting Indigenous nurses and has developed a guide to empower healthcare professionals to address racism.
futurumcareers.com/health-is-we...

Join us for an online symposium exploring the evidence behind lifestyle factors and their impact on health &wellbeing.

Hear from expert speakers, engage with current research, & gain practical insights relevant to clinical & research settings.

💻 Online symposium
🔗 Register now : lnkd.in/gqhzZqiH

Glucocorticoid Injections in Knee Osteoarthritis

A randomized clinical trial of 60 patients found that glucocorticoid injections into the infrapatellar fat pad (IPFP) did not significantly reduce pain scores in patients with inflammatory knee OA (compared to placebo).

buff.ly/9MNYlHH

Mechanomedicine - Nature Reviews Bioengineering Mechanical forces are crucial regulators of biological functions in health and disease, offering measurable biomarkers and therapeutic targets. This Review introduces the principles of mechanomed...

www.nature.com/articles/s44...

Mans not hot...

Never hot.

Editorial

Understanding the Resolution of Clinically Suspect Arthralgia: Moving Forward, but Challenges Remain

📖 doi.org/10.3899/jrhe...
@cu-kidney.bsky.social

#Biomarkers #DiseaseProgression #RheumatoidArthritis

"These findings demonstrate that the detection and interpretation of OA-related alterations in chondrocyte mechanobiology are strongly dependent on the dimensionality and degradable properties of the culture system."

Osteoarthritic chondrocytes exert higher contractile forces and exhibit enhanced protrusive activity when cultured in 3D degradable hydrogels Osteoarthritis (OA) induces phenotypic changes in chondrocytes as well as alterations in matrix composition and mechanics. Yet, its impact on active c…

"OA alters the expression + organisation of proteins involved in force exertion + transmission across both 2D + 3D cultures, but only in a 3D degradable hydrogel environment do these changes translate into higher cell-generated contractile forces"

www.sciencedirect.com/science/arti...

Get vaccinated #PublicHealth

Breakdown of materials evaluated, with the number of studies evaluated for each (#) and the associated animal models used. (Note: 6 of the 24 studies were comparative studies that evaluated two or more HBMs). Titanium (Ti), Cobalt Chromium (CoCr), Stainless Steel (SS), Alumina Ceramic (AC), Pyrolytic Carbon (PyC), Partially Stabilized Zirconia (PSZ), Zirconia Dioxide (ZrO2), Polyetheretherketone (PEEK), Polyvinyl Alcohol (PVA).

Check out "In Vivo Evaluation of Hemiarthroplasty Bearing Materials Using Animal Models: A Scoping Review (Part II)", by Landon M. Begin & coauthors in JOR: onlinelibrary.wiley.com/doi/10.1002/...

Figure showing specialist nephrology management of chronic kidney disease. Copyright: 2025 The Author(s). Published by Elsevier Ltd. CC BY 4.0.

By 2050, chronic kidney disease (CKD) is projected to become the fifth leading underlying cause of death worldwide.

A new Seminar provides a simple approach to CKD diagnosis, staging, and management that can be applied in most clinical settings: spkl.io/63323AlsFF

“The original plan was for the Medical Research Future Fund […] to disburse about $1 billion annually once it reached maturity at $20 billion. But that has not happened, and the government is instead releasing $650 million a year.”

Meanwhile us researchers are left dejected an burnt out.

Comorbidity and Health Management: Tuesday Night Rheumatology

Join panelists Vanessa Hill, NP-C, Lindsay Tom, PA-C, Barb Slusher, MSW, PA-C and Jack Cush, MD as they discuss comorbidity and health management in rheumatic disease.

buff.ly/igZwTQn

Scientists retrieve RNA from an extinct animal, marking a first in genetics research Researchers in Sweden recovered RNA from a 130-year-old Tasmanian tiger, allowing them to identify which genes were active in its tissues before extinction.

Scientists retrieve RNA from an extinct animal, marking a first in genetics research

share.google/et9vTjZxn3Wt...

New developments and old battles: Australia's health year in 2025 As with most years, the health sector has been a constant source of news stories - from outbreaks of illnesses to outstanding medical research, from politics to pandemics, from injuries to infections....

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www.sbs.com.au/news/podcast...