Scripps Research

Last weekend, Scripps Research joined thousands of riders, runners and walkers at this year’s #CureboundCancerChallenge! Thank you to everyone who supported our team—your generosity helps fund collaborative cancer research. There’s still time to give before August ends—give now at: ow.ly/K63F50Wzze2

Scripps Research awarded $1.7 million by NIH to advance biomedical data integration and AI-powered discovery

The NIH awards Scripps Research Professors @andrewsu.bsky.social, & Chunlei Wu, PhD $1.7M from NCATS to power the Biomedical Data Translator program—creating an open-source platform that integrates data across genomics, pharmacology, clinical research, patient care and more.

More: ow.ly/p86E50WuSpl

Life beyond Crohn’s disease - Scripps Research Magazine After enduring decades of complications from Crohn’s disease, Gary Jacobson received a pioneering treatment from a Scripps Research professor that gave him relief and a renewed sense of control.

After enduring decades of complications from Crohn’s disease, Gary Jacobson received a pioneering treatment from Scripps Research professor and colorectal surgeon Amy Lightner: stem cell injections for perianal fistulas. The results changed his life.

Seeing translational research in real time at #ScienceinAction, following @scripps.edu EVP Eric Topol’s Front Row lecture! Guests explored tools used by the Digital Trials Center in their public studies, with the chance to enroll.

Watch @erictopol.bsky.social's full lecture at: frontrow.scripps.edu

What can you expect to learn at #IBDCuttingEdge2025? Clinical trials, emerging therapies, surgical strategies, and patient-centered models—all designed to improve outcomes in IBD care & advance future therapies.

Join us on:
📅 Sept 19–21
📍 Coronado, CA
🎟️ Register now: ow.ly/uoJ550Wuctu

We can predict a person's risk of coronary artery disease better than ever before. Cover of new
@naturemedicine.bsky.social
regarding our @scripps.edu recent paper
nature.com/articles/s41...

Behind every cure is someone who believed in the power of science. Philanthropy is essential to Scripps Research.

Your gift helps our scientists turn bold research into real hope in cancer, brain disease and other urgent health challenges.

To help support Scripps Research, visit: ow.ly/3rLb50WqN6Q

Where did RNA come from?

Where did RNA come from? A new study from @scripps.edu found that ribose binds to phosphate—another molecular component of RNA—more quickly and effectively than other sugar molecules. This feature could have helped select ribose for inclusion in the molecules of life.

Professor and Nobel laureate Ardem Patapoutian (@ardemp.bskyverified.social) is studying pain at the cellular level to develop new therapies. His team is transforming our understanding of physical sensation—and how those insights could lead to better treatments for chronic pain. ow.ly/pf0S50WqeFZ

Scripps Research clinical trial fights cancer with novel on-off switch New research explores ‘switchable’ T cells, possibly allowing safe treatment of solid tumors

#ICYMI: @nbcsandiego.com & @sandiegouniontribune.com featured the first trial of switchable CAR-T therapy for breast cancer by @scripps.edu & Calibr-Skaggs, using engineered T cells to attack tumors with precise control and potential for long-term remission.

🎥 ow.ly/tl1S50WrYNZ
📰 ow.ly/o2un50WrYOL

Today’s the day! Join us at 1PM PT for the second installment of our virtual masterclass summer series.

To join this session or learn more about the Biotech Innovation Summit, contact biotechsummit@scripps.edu

Tiny chip speeds up antibody mapping for faster vaccine design

A new microchip invented by @scripps.edu shows how antibodies interact with viruses using just a drop of blood.
The system, called microfluidic EM-based polyclonal epitope mapping (mEM), uses ~100x less blood than previous methods and completes the process in ~90 minutes. @natbiomedeng.nature.com.

As we age, the body’s ability to repair and replace tissue declines, leading to illness and infirmity.

To address this, Calibr-Skaggs and Scripps Research scientists are developing drugs that coax a patient’s own stem cells to regenerate healthy tissue. More: magazine.scripps.edu/features/202...

Viome and Scripps Research partner to develop first at-home RNA screening test to prevent colon cancer before it strikes

Viome Life Sciences and Scripps Research today announced a strategic partnership to develop and clinically validate the first at-home RNA test designed to detect precancerous colon polyps as colorectal cancer rises in adults under 50, enabling early prevention of colorectal cancer.

Join us on July 17 for the second installment of our virtual masterclass summer series where founders and pharma partners share what real early engagement looks like.

To join this virtual masterclass and learn more about this year's Biotech Innovation Summit, email us at biotechsummit@scripps.edu.

The Venom Vanquisher - Scripps Research Magazine Irene Khalek is on a quest to design a universal antivenom and protect people around the world from the deadliest snakebites. Across cultures, countries and mythologies, snakes are often associated wi...

Roughly 100,000 people die each year from venomous snakebites. To change that, Irene Khalek, PhD, a staff scientist in the Jardine lab at Scripps Research, is designing a universal antivenom that could protect against all medically relevant snakebites.

At Science in Action, a new Front Row post-lecture activity, the Lairson lab showed attendees how they apply cellular and molecular techniques to drive myelin repair, from guiding stem cell differentiation to modeling neural signaling.

Watch Luke Lairson’s full lecture: frontrow.scripps.edu

Medicines without borders - Scripps Research Magazine Calibr-Skaggs scientists are advancing innovative medicines to help the world prepare for the next pandemic and transform medical care in regions that lack access to essential health services. Drug di...

What if the future of medicine prioritized access over profit?

Calibr-Skaggs scientists are advancing single-dose treatments and chemical vaccines to address health challenges long overlooked by industry. Read the full feature:

Jin-Quan Yu selected for the 5th Akira Suzuki Award - Scripps Research Magazine Jin-Quan Yu, the Bristol Myers Squibb Endowed Chair in Chemistry and the Frank and Bertha Hupp Professor in Chemistry at Scripps Research, has been selected as the recipient of the 5th Akira Suzuki Aw...

Prof. Jin-Quan Yu will receive the 5th Akira Suzuki Award for his research on C–H bond activation, which makes it easier to build complex molecules. His work accelerates advances in pharmaceuticals, molecular tools and materials science.

Congrats to Prof. @donnablack.bsky.social, recipient of the 2025 Centenary Prize for Chemistry and Communication from @rsc.org—awarded for pioneering work in kinetic methods of organic catalysis, asymmetric catalysis mechanisms, homochirality, and excellence in communication. More: ow.ly/iFhM50Wgn0z

YouTube video by Scripps Research A new metastatic breast cancer trial with a "switchable" CAR-T therapy

Calibr-Skaggs has dosed the first patient in a phase 1 trial evaluating CLBR001 + ABBV-461, a novel switchable CAR-T cell therapy for metastatic breast cancer.

The therapy is being tested in solid tumors for the first time, in collaboration with AbbVie. More at: ow.ly/TOpA50Wb1QG

This year on #SCL, we’ve had some amazing scientists join us to share their work, their stories and what drives them.

There’s one question we love to ask our guests: What advice would you give to scientists just starting out? Hear what they had to say: ow.ly/5l2s50WagBV

Kristian Andersen elected to Norwegian National Academy of Science and Letters - Scripps Research Magazine Infectious disease researcher and Scripps Research professor Kristian Andersen, PhD, was elected to the Norwegian Academy of Sciences and Letters, an organization founded in 1857 to support and promot...

Congratulations to @kgandersen.bsky.social, who was elected to the Norwegian Academy of Sciences and Letters for his contributions to infectious disease research, which include understanding the emergence and evolution of viruses such as Ebola, Lassa, Zika, Mpox and SARS-CoV-2.

Two-part vaccine strategy generates a stronger, longer-lasting immune boost against HIV

In a study published in Science Translational Medicine, part of @science.org, Scripps Research scientists show that pairing two vaccine adjuvants elicits a stronger, longer-lasting immune response against HIV in a preclinical model.

FDA approves ENCELTO, a first-of-its-kind eye implant that slows vision loss in rare eye disease

The @fda.gov has approved ENCELTO, a first-of-its-kind eye implant that slows vision loss in rare eye disease.

The cell-based therapy developed by Neurotech Pharmaceuticals with roots at Scripps Research offers new hope for patients with MacTel type 2.

Diversifying the reference iPSC line concept We discuss how to diversify the reference iPSC line concept. We highlight workflows for generating diverse iPSC lines. We ask whether reference lines can act as inclusive sources of human diversity fo...

A new @cp-cellstemcell.bsky.social article co-authored by Scripps Research Prof. Jeanne Loring calls for genetically diverse reference iPSC lines to better benchmark disease modeling, drug testing, and regenerative medicine.

A major concern this flu season is reassortment, when seasonal flu and bird flu infect the same host and swap genetic material, potentially creating a new, more dangerous strain. With H5N1 in cows and human cases emerging, our virology labs are closely tracking its evolution. More: ow.ly/thLP50WafhH

Last Tuesday, Scripps Research hosted its third Biotech Salon—with Savills and UBS—to foster dialogue among biotech innovators and the scientific community.

We heard from a distinguished panel, all deeply connected to Scripps Research, discussing the challenges and opportunities shaping the field.

Females may be more biochemically sensitive to alcohol—long before dependence sets in

Females may be more biochemically sensitive to alcohol, long before dependence sets in.

A Scripps Research study could help guide personalized treatment strategies for alcohol use disorder, especially for women and those in early stages of harmful use. ow.ly/7kSf50W7YLv

Females may be more sensitive to alcohol – rat study Researchers from the USA found that changes in the brains of female rats exposed to alcohol appear earlier than in males, potentially guiding personalised treatments for women.

♀️ ♂️ New study at‪ @scripps.edu found that changes in the brains of female rats exposed to alcohol appear earlier than in males, potentially guiding personalised treatments for women.

Learn more: www.eara.eu/post/females...

#AnimalResearch #dependence #alcohol