Mathew Piasecki

**Come work with us!!**

Three-year post-doc position funded by Parkinson's UK available Cardiff University - using TMS to study inhibition of planned stepping movements and better understand freezing of gait. Full details here - krb-sjobs.brassring.com/TGnewUI/Sear...

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Postdoctoral Research Fellowship (286516) | University of Oslo Job title: Postdoctoral Research Fellowship (286516), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025

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2 new positions in the lab as postdoc & PhD!

Interested in stress, pain, or reward? This project has it all!

We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶

www.jobbnorge.no/en/available...

New 3-year PostDoc opportunity in CoMAP, funded by UKRI-BBSRC — developing innovative methods to study motor unit adaptation to ageing and its functional consequences in humans. Please pass on to any who may be interested.

@ukri.org
jobs.nottingham.ac.uk/Vacancy.aspx...

New paper - Sex differences in healthy brain aging are unlikely to explain higher Alzheimer’s Disease prevalence in women: https://doi.org/10.1073/pnas.2510486122

Postdoctoral Research Associate in Muscle Biology and Genomics | King's College London

🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important

Good collab with @droch.bsky.social so travel to CPH involved as well

www.kcl.ac.uk/jobs/126245-...

We had a little appearance on Channel4 last night; Michael Mosley: Secrets of the Superagers

Michael came to our lab and tried a few of our methods, including needle EMG

See 36 mins in for some pretty good spikes 😎

www.channel4.com/programmes/m...

Mathew Piasecki of uniofnottingham.bsky.social discusses motor unit adaptation to disuse: crossing the threshold from firing rate suppression to #neuromuscular junction transmission ⚙️ 🔎

📖 Read the #TopicalReview here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Penultimate presentation from our group at @northumbriauni.bsky.social is @elisanedelec.bsky.social presenting her work on knee extensior neuromuscular function across the menstrual cycle at @ecssofficial.bsky.social in Rimini, Italy 🇮🇹

Second up from our group from @northumbriauni.bsky.social is @padraig-spillane.bsky.social presenting his work titled Contraction intensity-specific fluctuations in motor unit behaviour across the menstrual cycle at @ecssofficial.bsky.social in Rimini, Italy 🇮🇹

francoishug.bsky.social‬ et al. investigated non-homogeneous distribution of inhibitory inputs among #motor units in response to #nociceptive stimulation at moderate contraction intensity ⚙️ ✍️

📜 Read the #Research here: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP288504

Chronic resistance and endurance training alters the way in which motor unit discharge rates are modulated across contraction intensities, suggesting alterations in net excitatory synaptic input - another fun collaboration with @jskarabot.bsky.social and colleagues.

www.biorxiv.org/content/10.1...

Non‐homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity Abstract figure legend We combined experimental data and in silico models to investigate the contribution of inhibitory and neuromodulatory inputs to motor unit behaviour in response to nociceptive s....

🆕📝 New publication in @jphysiol.bsky.social “Non-homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity”
🔗 doi.org/10.1113/JP28...
@univcotedazur.bsky.social @simonavrillon.bsky.social @agencerecherche.bsky.social

Senior Editors Paul. L. Greenhaff & Harold D. Schultz examine the central role of human and clinical physiology in the era of multi-omics and inter-organ crosstalk ✍️

🔗 Read the #Editorial here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Load and muscle‐dependent changes in triceps surae motor unit firing properties in individuals with non‐insertional Achilles tendinopathy Abstract figure legend Motor unit firing properties of the medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SO) muscles were assessed using high-density surface electromyography (HD....

‘Load and muscle-dependent changes in triceps surae motor unit firing properties in individuals with non-insertional Achilles tendinopathy’ Our latest study has just been published in @jphysiol.bsky.social - open access below

A subcortical switchboard for perseverative, exploratory and disengaged states - Nature Behavioural experiments in mice demonstrate that GABAergic (γ-aminobutyric acid-expressing), glutamatergic and serotonergic neurons in the median raphe nucleus have distinct and complementary function...

The revival of an old metaphor, first coined by Henri Bergson in the 1880s - the brain is (or has) a switchboard!

Tomomichi Oya of @westernuwin.bsky.social writes this #Perspective on Dernoncourt et al. (2025), as their experimental results raise several important considerations regarding MU #flexibility 💭

🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Job Alert (please repost)!

We are looking to hire a Research Assistant to join us in an exciting project looking into Brain-Computer Interfaces (BCIs) and how brains learn to control them.

📣 CALL FOR PAPERS 📣

Organised by @pgreenhaff.bsky.social & focusing on:

🚑 Injury and rehabilitation
⛰️ Altitude physiology
🦵 Muscle adaptation
🚴 Exercise training
💉 Pharmacological interventions
⚙️ Body composition

🔗 buff.ly/2sVbnLk

Job Vacancy at the University of Nottingham: Research Assistant (Fixed Term) We seek a predoctoral research assistant to join the Humphries’ group at the University of Nottingham on a BBSRC-funded project to study the neural basis of foraging, in collaboration with the groups ...

My lab is hiring a pre-doctoral research assistant to work on the neural computations of foraging, seeking common cross-species algorithms. A BBSRC-funded project in collaboration with Matt Apps (Birmingham) & Nathan Lepora (Bristol)

Closes May 5th

Pls share!
jobs.nottingham.ac.uk/vacancy.aspx...

Here comes the sun: the central role of human and clinical physiology in the era of multi‐omics and inter‐organ crosstalk Click on the article title to read more.

Clinical and humans physiology to the fore. Think about submitting your work to The Journal of Physiology.

doi.org/10.1113/jp28...

Intrinsic properties of spinal motoneurons degrade ankle torque control in humans Abstract figure legend All motor commands are processed via spinal motoneurons, whose intrinsic electrical properties are adapted by brainstem neuromodulatory inputs. The effects of these neuromodula....

New pub from Drew in CJ’s lab. We showed prolonged firing of motoneurons makes it hard to control force, estimates of PICs are larger at short muscle lengths, and combining the two exacerbates this prolongation of firing-induced force variability.

physoc.onlinelibrary.wiley.com/doi/full/10....

Research Associate in Neurophysiology of Amyotrophic Lateral Sclerosis at Loughborough University Apply now for the Research Associate in Neurophysiology of Amyotrophic Lateral Sclerosis role on jobs.ac.uk - the leading job board for higher education jobs. View details.

Exciting two-year postdoc position available in neuromuscular physiology!

www.jobs.ac.uk/job/DML152/r...

À la recherche du temps perdu: will AI and 150 years of human movement research drive the next Neuroscience revolution? Click on the article title to read more.

…been silent for a while, reappeared with a piece in @jphysiol.bsky.social on #MotorControl #Neurophysiology and #AI #history -> behavioral research holds valuable insights that new AI methods can leverage to understand brain function.
tinyurl.com/cbc64ff6
#neuroscience #NeuroAI #cognitivescience

Acute Intermittent Hypoxia in People Living With Chronic Stroke: A Case Series | Stroke BACKGROUND: Acute intermittent hypoxia (AIH) is a novel therapeutic intervention that facilitates recovery of function, but the tolerability and effectiveness have not been tested in people living wit...

Our recent case series on the tolerability and safety of acute intermittent hypoxia in people living with chronic stroke is now available online at Stroke. Initial results are positive, with much more work needed to refine protocols and confrim effectiveness www.ahajournals.org/doi/10.1161/...

Blue plaque review series: A.V. Hill, athletic records and the birth of exercise physiology Abstract figure legend Depiction of the world running records from 1925 studied by A. V. Hill and those of 2025 up to and including ultradistance events on a semi-logarithmic plot. These records, in ...

A.V. Hill was a hero, a genius, and the most upright person Bernard Katz ever met. He helped bring exercise physiology into being. Here’s our review of that story, published in @jphysiol.bsky.social. physoc.onlinelibrary.wiley.com/doi/full/10....

Our latest preprint, using startling acoustic stimuli in combination with neurostimulation to better understand the neural mechanisms of fatigue 🧠

🚨ONLY 2 DAYS LEFT TO APPLY🚨

To our 2025 Editorial Board Fellowship scheme!

Read about Andrew Holmes' experience as an Editorial Fellow🎓👇

How to apply: 🔗https://buff.ly/2s5K83y

Flexible control of motor units: is the multidimensionality of motor unit manifolds a sufficient condition? Abstract figure legend We recorded large populations of motor units from the vastus lateralis (VL) and gastrocnemius medialis (GM). Using a linear dimensionality reduction approach, we observed that ....

🆕 🚩 Check out our latest publication in @jphysiol.bsky.social led by F. Dernoncourt 👨‍🎓👏: "Flexible control of motor units: Is the multidimensionality of motor unit manifolds a sufficient condition?" - 🔗 urlr.me/x3uVGE @univcotedazur.bsky.social @agencerecherche.bsky.social @simonavrillon.bsky.social

🚨 Registration Open! 🚨

Join us in Brescia 🇮🇹 for the INcEPTION Winter School 2025 on HDsEMG!

📅 10th–14th March 2025
📍 In-person only | Limited spots!
✅ No registration fee

Don't miss this opportunity! Find further details here: forms.gle/EY4wNMnbYRn9nT…

Periop people - a colleague from @uniofnottingham.bsky.social is developing a consensus on the impact of prehabilitation on postoperative cognition among patients >65. Here’s an online thingy… forms.office.com/e/QW7JKaBhfz #AnSky #GeriSky #SurgSky @adamgordon1978.bsky.social @cpoc.bsky.social