Dementias Platform UK

Even a few thousand steps a day can reduce your risk of Alzheimer’s – new study Even modest amounts of walking – as few as 3,000 steps a day – may help protect against Alzheimer’s by reducing harmful tau proteins in the brain.

Happy Friday! 🎉

Weekend plans? New research shows just 3,000 steps a day (30 min walk) could cut Alzheimer's risk by nearly half 🧠👟

Optimal: 5,000-7,500 steps. Get outside, grab a friend, enjoy nature.

Every step counts!

zurl.co/gSyQy

#HappyFriday #BrainHealth

New Paper from @dementiasplatform.bsky.social researchers FatemehTabassi Mofrad and Chris Patrick Pflanz. Their findings offer a guide for regenerative strategies and therapeutic interventions by locating subcortical regions most vulnerable to age-related atrophy and inflammation.
zurl.co/HEjQM

Congratulations to Dishaa Sinha, one of the many outstanding women working with @dementiasplatform.bsky.social for her award at #WINAwards2025. She has done great work on our #FAST study and #GreatMinds register. #dementiaresearch #cognition #bloodbiomarkers #ageing #aging 👏👩‍🔬

Physical activity as a modifiable risk factor in preclinical Alzheimer’s disease - Nature Medicine In cognitively normal older adults at risk for Alzheimer’s dementia, physical inactivity was associated with faster tau protein buildup and cognitive decline.

Physical activity as a modifiable risk factor in preclinical Alzheimer’s disease www.nature.com/articles/s41...

Have you ever thought of studying at #Oxford?
#psychiatry

Points West - Evening News: 04/11/2025 The latest news, sport, weather and features from the West of England.

Great to see READ-OUT study and the #BloodBiomarkerChallenge leading the news on Points West zurl.co/Sg16V
Both @researchnbt.bsky.social and
@reminduk.bsky.social are participating in the study. It could revolutionise #dementia #diagnosis @alzheimerssoc.bsky.social @alzheimersresearchuk.org

Dr Delia Gheorghe & Prof Sarah Bauermeister discussed their @DementiasUK research on Pro TV News Romania (interview in Romanian).

Great to see dementia research reaching international audiences!

👉 Watch the interview: zurl.co/QHi9d

#DementiaResearch #SciComm

A fantastic new milestone for the @dpukdataportal.bsky.social which has passed last year's record access requests - hitting 150 so far in 2025. AND we've had over 2,500 dataset requests too. Continued growth for an extraordinary #dementia #research resource. #aging #cognition

READ-OUT is combining blood and digital tests to assess #dementia. New funding for two digital tests comes from Innovate UK (UKRI). Find out more zurl.co/VmhBG Using blood & #digital tests together may be a way of speeding up a #diagnosis, widening access in the NHS.

YouTube video by Dementias Platform UK DPUK Great Minds | Saïd Business School, Oxford, 16 Oct 2025

Great Minds event 'Decoding Dementia: Biomarkers, Big Data, and the Future of Diagnosis' is now available to watch 🧠

Featuring #DPUK experts discussing blood-based biomarkers, AI, and NHS readiness

Watch here: www.youtube.com/watch?v=kvQE...

#DementiaResearch #Biomarkers

We're live at The Saïd Business School, Oxford!

Our Great Minds event is underway with Prof John Gallacher presenting on big data and dementia insights.

More from Prof James Rowe, Prof Vanessa Raymont & Dr Ivan Koychev to come!

#GreatMinds #DementiaResearch

Congratulations to our NTAD team for a paper in @molpsychiatry - A study assessing new biophysical models of non-invasive human #MEG imaging to test pharmacological and disease modulation of NMDA-receptor inhibition.
zurl.co/VWbGK
#dementia #alzheimers #dpuk

Dementia is a global challenge. On World Mental Health Day, #DPUK wants to thank every single research scientist dedicated to better understanding the disease...and each study volunteer helping them too. #dementia, declining #cognition, #MND and #Parkinsons.

#35AEC in Bologna - and 2 presentations from @DementiasUK in the Brain Health session.
Congratulations to Megan Smith (MIND Diet and Aging) and Pippa Watson (Lifestyle factors & SuperAgers) for excellent talks about their research.
#dementia #alzheimers #cognition @alzheimereurope.bsky.social

DON'T MISS THIS EVENT if you are part of the #READ-OUT study or working at a research centre. It's a chance to hear about some of the latest research areas for dementia: biomarkers, AI & diagnosis.
In Oxford: zurl.co/1T7fO
Or ONLINE: zurl.co/LpgW6

Don't miss it! Book your place at our latest GREAT MINDS LIVE event - in Oxford (and online). Decoding Dementia: Biomarkers, Big Data and the Future of Diagnosis. FREE, but places are limited.

Attend in person: zurl.co/3aacq
Online: zurl.co/vUa6g

Lewy body dementia promotion by air pollutants Evidence links air pollution to dementia, yet its role in Lewy body dementia (LBD) remains unclear. In this work, we showed in a cohort of 56.5 million individuals across the United States that fine particulate matter (PM2.5) exposure raises LBD risk. ...

Health data research reveals #LewyBody risk from air #pollution.
Fine-particulate air pollution can lead to #dementia. Triggering the formation of toxic clumps of protein they destroy nerve cells as they spread through the brain.
zurl.co/65v5r

🧠 GREAT MINDS LIVE - 16 October, 2-5pm
Join leading #DPUK experts exploring blood #biomarkers, #AI, and research registers in #dementia
📅 Thursday 16th October, 2-5pm
📍 Said Business School
💰 FREE
Book:
Venue zurl.co/n7Npj
Online zurl.co/wbTus

Prof Sarah Bauermeister has been speaking at the #TBI-Reporter conference today about curation of data at scale. At #DPUK she developed the #C-Surv #ontology enabling highly effective data management. #braininjury #dataanalysis # dementia #trauma @oxfordpsychiatry.bsky.social

It's great to hear about the huge amount of work going on with traumatic brain injuries at the TBI_REPORTER General Assembly this week. A key resource is its #hub hosted on #DPUK's data portal (@dpukdataportal.bsky.social) - which is collating & curating #braininjury research data at scale. #TBI

Great to have DPUK engaged at #VasCog 2025 yesterday. Notable contributions from #AtticusHainsworth and #JoannaWardlaw. We are looking forward to some really interesting #DPUK #vascular #dementia research in future, building on our existing work. #cognition #brain @ukdri.ac.uk

Doctors trial £100 blood test that could transform how NHS detects Alzheimer’s More than 1,000 patients to take part in trial to see if the approach leads to faster and more reliable diagnoses

We're delighted to welcome the launch of ADAPT, a study focused on p-tau217 as a potential biomarker to use in a simple blood test to diagnose dementia. It joins our own READ-OUT project in the Blood Biomarker Challenge to find a test to use in NHS brain clinics.
www.theguardian.com/society/2025...

GREAT MINDS LIVE - Booking to attend 'in person' The future of biomarkers and the importance of registers in dementia research

🧠 GREAT MINDS LIVE - 16 October, 2-5pm: The Future of #DementiaResearch

Join leading #DPUK experts exploring blood #biomarkers, #AI, and research registers in #dementia

📅 Thursday 16th October, 2-5pm
📍 Said Business School
💰 FREE

Please register: zurl.co/n7Npj

If you are putting together a clinical study or trial for dementia, our Great Minds register volunteers are ready to help. We know a lot about them, making it easier to accurately select appropriate candidates and save you time during selection. Find out more: zurl.co/bBiaV

With 107 multimodal datasets - accessible in one place - the #DPUK Data Portal is a fundamental tool for dementia research. Data includes lifestyle, cognition tests, brain imaging, and genetics. Check it out. Use our Discovery Tools zurl.co/Klv2R

Our Trials Delivery network is a valuable asset for putting together a clinical dementia trial. Check out what's on offer at 80 sites across the UK. See the interactive map. Locations from Shetland to Cornwall. Easy to use. Curious? You should be! zurl.co/jVBef

Your brain's "guardian" cells might hold the key to Alzheimer's risk! 🧠 New study shows genetic factors act at the brain's border, not just neurons. Game-changer for therapies? zurl.co/9PfcS #DPUK #AlzheimersResearch

The Times Features participant voices from READ-OUT study We're pleased to share Anna Maxted's thoughtful feature in The Times, published yesterday: "The dementia patients who could change lives". Her story captures the personal experiences of volunteers participating in the DPUK READ-OUT study, part of the Blood Biomarker Challenge. We're grateful to Beverley Evans and Stephanie Everill for generously sharing their stories with The Times. Their willingness to share their personal experiences helps us in reaching a wider audience to talk about the valuable research we are doing to bring blood biomarkers for dementia into common usage within the NHS.

The Times features READ-OUT study participants in "The dementia patients who could change lives" Beverley Evans: "I want to take part and help... Not for myself, but I don't want my kids to have it."
Our Blood Biomarker Challenge is working to make dementia diagnosis more accessible.
zurl.co/NgBJR

Vaccines hold tantalizing promise in the fight against dementia A prominent Nature study and related research raise the possibility that vaccines may have a broader role in experimental therapeutics outside the realm of infectious diseases.

💉 Could your routine jab protect your brain? New research shows vaccines for shingles, tetanus & pneumonia may reduce dementia risk. "Trained immunity" could be key to cognitive protection. Read more: zurl.co/jb1BY

#BrainHealth #DementiaPrevention #Innovation #DPUK

🧠 New blog from PhD researcher Megan Smith: How the MIND diet shows cognitive benefits 12+ years later, whilst ultra-processed foods increase dementia risk.
"Food has the potential to either support or hinder our brains"
Read more: zurl.co/3JDkk#DementiaResearch #DPUK