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Natasha Krishnadas

@natashakrishnadas.bsky.social

Cognitive Neurologist | Clinical trials physician | Post-doc | Dementia | Neuroimaging | Tau | proteinopathies

100 Followers  |  232 Following  |  2 Posts  |  Joined: 21.11.2024  |  1.4463

Latest posts by natashakrishnadas.bsky.social on Bluesky

So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! ๐Ÿง 

๐Ÿ™ I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this ~5min survey: alz.surveymonkey.com/r/923BTQK

28.04.2025 18:26 โ€” ๐Ÿ‘ 11    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimerโ€™s disease - Nature Medicine Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimerโ€™s disease and enables the detecting and tracking of Alzheimerโ€™s clinical impairment.

We now have a blood biomarker that is even more strongly associated with tau PET and cognitive symptoms than even p-tau217! Plasma eMTBR-tau243 will help us to understand whether cognitive impairment is likely to be related to Alzheimer's pathology. #ENDALZ

www.nature.com/articles/s41...

31.03.2025 14:56 โ€” ๐Ÿ‘ 47    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Comparison Between Brain and Cerebellar Autoradiography Using [18F]Flortaucipir, [18F]MK6240, and [18F]PI2620 in Postmortem Human Brain Tissue Our objective was to evaluate the inย vitro binding properties of [18F]flortaucipir, 6-(fluoro-18F)-3-(1 H -pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]MK6240), and 2-(2-([18F]fluoro)pyridin-4...

๐Ÿ“„ In a new study just published in the Journal of Nuclear Medicine, our PhD student #AntonioAliaga, in collaboration with #Prof.PedroRosa-Neto's team, evaluated the binding properties of tau radiotracers in postmortem human brain tissue in the context of AD. ๐Ÿ‘‡ 1/n jnm.snmjournals.org/content/earl...

25.11.2024 18:25 โ€” ๐Ÿ‘ 17    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Neuronal and oligodendroglial, but not astroglial, tau translates to in vivo tau PET signals in individuals with primary tauopathies - Acta Neuropathologica Tau PET has attracted increasing interest as an imaging biomarker for 4-repeat (4R)-tauopathy progressive supranuclear palsy (PSP). However, the translation of in vitro 4R-tau binding to in vivo tau P...

Massive paper alert: We performed extensive profiling of PI-2620 for 4R tauopathies. PI-2620 tau PET signals in PSP stem from neuronal and oligodendroglial tau, not astrocytes. Signals correlate with fibrillary tau, autoradiography, and autopsy data in PSP
doi.org/10.1007/s004...

25.11.2024 17:59 โ€” ๐Ÿ‘ 29    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Starting in 30 mins! Join us for the ISTAART PEERS Journal Club: presentation and discussion of how ECR's are considered and supported on a national level by dementia plans and organisations

21.11.2024 21:27 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Could I please be added to the list?

21.11.2024 11:12 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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