HCAR2 is a novel receptor for heme
Extracellular heme, released during intravascular hemolysis in sickle cell disease (SCD) and hemolytic anemia acts as a pro-inflammatory danger signal…
Excited to share my first last-author paper! Using in vivo models, transcriptomic analyses, and cellular assays, we demonstrate that HCAR2 acts as a receptor for heme, potentially forming a novel negative feedback loop that promotes Hmox1 expression.
www.sciencedirect.com/science/arti...
16.05.2025 10:30 — 👍 1 🔁 0 💬 0 📌 1
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