Cell Press

Spatial omics enters the microscopic realm: opportunities and challenges

Spatial omics enters the microscopic realm: opportunities and challenges
http://dlvr.it/TPlYQK

Hyun Min Kang, Jun Hee Lee & colleagues
@cp-trendsgenetics.bsky.social
#CellBio2025

Current Biology

Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1
http://dlvr.it/TPlS8Q

Dorota Wloga, Khanh Huy Bui & colleagues
@currentbiology@bsky.social
#CellBio2025

Cell Chemical Biology

RAGE-mediated activation of the formin DIAPH1 and human macrophage inflammation are inhibited by a small molecule antagonist
http://dlvr.it/TPlKHZ

Ann Marie Schmidt, Alexander Shekhtman & colleagues
@cp-cellchembiol.bsky.social
#CellBio2025

Centrosomes and cancer: balancing tumor-promoting and inhibitory roles

Centrosomes and cancer: balancing tumor-promoting and inhibitory roles
http://dlvr.it/TPl79P

@susanagodinho.bsky.social & Renata Basto
@cp-trendscellbio.bsky.social
#CellBio2025

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis
http://dlvr.it/TPh6Bf

Yifan Cheng, Chuankai Zhou & colleagues
@cp-molcell.bsky.social
#CellBio2025

Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells

Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells.
http://dlvr.it/TPgSRt

Sudipto Roy & colleagues
@cp-cellreports.bsky.social
#CellBio2025

Cell size matters: a unifying theory across the tree of life

Cell size matters: a unifying theory across the tree of life.
http://dlvr.it/TPgKwF

Marcin Czarnoleski (Jagiellonian University) & Wilco C.E.P. Verberk (Radboud University)
@cp-trendsecolevo.bsky.social
#CellBio2025

1918 Influenza victims crowd into an emergency hospital CREDIT AP Photo National Museum of Health

To effectively treat long #COVID, we must learn from historical chronic illnesses, medical researchers say. spkl.io/63328AgJFr

Akiko Iwasaki, Christine Miller, Janna Moen
@cp-trendsimmuno.bsky.social

Dog ownership during adolescence alters the microbiota and improves mental health. Highlights: Dog ownership in adolescence is linked to improved mental health Adolescents with dogs show distinct microbiota profiles Dog-related microbiota transfer enhances mouse social behavior Streptococcu s ASVs correlate with well-being in adolescents and mice

A family dog can boost teens' mental health through the microbiome, study suggests. spkl.io/63329AgJ2H

Takefumi Kikusui & colleagues
@cp-iscience.bsky.social

This schematic outlines the implementation of circular economy strategies—reduce (light blue), reuse (green), and recycle (yellow)—across five key stages in the space sector: material, design and manufacturing, launch, service, and end of life (EOL).

Scientists discuss how the principles of "reduce, reuse, recycle" could be applied to satellites and spacecraft. spkl.io/63325AgJ2F

Jin Xuan & colleagues
@cp-chemcircularity.bsky.social

Cell Symposia: Hallmarks of cancer

We're excited to host a distinguished lineup of speakers at @CellSymposia #CSHallmarks2026, including keynote speakers @johannajoyce.bsky.social & Faisal Mahmood @harvardmed.bsky.social. View the full speaker lineup: http://dlvr.it/TPbBqK

Enjoying the #Cell Press #reception in the #restaurant #Rochambeau in #Boston during the #F25MRS #conference with #snacks and #drinks and great #discussions with so many different #colleagues and #friends from all around the #world- thank you Steve Cranford (康福德) for the kind invitation!

Sustainability Forum

Critical minerals are shaping future tech.
Join the Sustainability Forum to explore supply chains, reuse, replacements & circular design & help build stronger, greener systems.
http://dlvr.it/TPZl6j

Leopard cats lived commensally with humans in ancient China for over 3,500 years before domestic cats were introduced via Silk Road merchants around 1,400 years ago. Ancient DNA shows that while two small felids once occupied anthropogenic environments, only domestic cats became fully domesticated and globally distributed.

"The late arrival of domestic #cats in China via the Silk Road after 3,500 years of human-leopard cat commensalism" spkl.io/63320AdF6i

He Yu, @joel-alves.bsky.social, @gregerlarson.bsky.social, Shu-Jin Luo & colleagues
#CellGenomics

Charles et al. rediscover the presumed - extinct greater chestnut weevil (Curculio caryatrypes) in the eastern US via iNaturalist, and genomic data and field surveys confirm identity and active reproduction, revealing persistence despite American chestnut collapse and underscoring the power of digital platforms for biodiversity research and conservation

"Rediscovery of the greater chestnut #weevil highlights the power of digital platforms in biodiversity research and conservation" spkl.io/63326Ad07u

@Michael A. Charles & colleagues
@currentbiology.bsky.social

Acute stress causes immediate hair follicle necrosis and hair loss via sympathetic nerves, which in turn activates and expand s autoreactive CD8 ⁺ T cells targeting hair follicles. Thus, a single stress event not only causes immediate tissue damage but also predisposes the tissue to future autoimmune attack.

"Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity" spkl.io/63326Ad0f6

Ya-Chieh Hsu & colleagues
@cp-cell.bsky.social

Remarkable cycling performance from commonplace powders (A–F) Various powders used as electrode additives. (G) Corresponding full-cell performance.

"Everything works, almost: A perspective on material evaluation in aqueous battery research" spkl.io/63327Ad0NP

Chao Wang, Zhoulu Wang & colleagues
#Joule

Potential strategies to overcome the political constraints on academic and biopharma drug discovery needs: public engagement, monetizing core services, repurposes molecules with AI, diversity funding, earlier asset commercialization, increase global collaboration

Researchers outline strategies to keep drug discovery research alive in the US despite funding cuts. spkl.io/63329AdFrl

@collabchem.bsky.social & Barbara Slusher
@cp-trendspharma.bsky.social

Sporophyte sample from the space exposure experiment on the ISS CREDIT Tomomichi Fujita

Highlights: P. patens spores survive simulate d space conditions with high resilience. Over 80% of spores remained viable after 9 months outside the ISS. Sporangiu m may provide protection against UV, heat, and intensive light stresses. Bryophyte could be used for planetary greening and life support systems.

This #moss survived 9 months directly exposed to the vacuum space and could still reproduce after returning to Earth. 🌚 🌿 spkl.io/63322AdFrp

Tomomichi Fujita & colleagues
@cp-iscience.bsky.social

A picture of Fusarium venenatum. Credit: Xiao Liu

Genetically engineered #fungi are protein packed, sustainable, and taste similar to meat. spkl.io/63325AdFr3

#JiangnanUniversity Xiao Liu & colleagues
@cp-trendsbiotech.bsky.social

Yi et al. show that environmental exposures such as smoking and biofuels elevate the abundance and mobility of human respiratory antibiotic resistance genes, which are associated with impaired lung function. These findings translate to a phenotypic resistance in mouse lung, highlighting the need for tackling pollution to combat antibiotic resistance.

"Environmental exposure augments the abundance and transferability of antibiotic resistance genes in the respiratory tract" spkl.io/63323AdlHR

Xue-yan Zheng (郑雪燕), Zhang Wang & colleagues
@cp-cellreports.bsky.social

Join us Nov 28 at STOC Plant 2025 in Beijing for a workshop on Spatiotemporal Omics for Plant Ecosystem Resilience with speakers Margaret Byrne, Peter Harrison, Marta Ibañes Miguez, Jiyun Kim, Jun Liu, Kohlen Wouter, Paul Nevill, and Yong-Guan Zhu. http://dlvr.it/TPNTSC

Fusarium graminearum (F. graminearum) pathogen induces wheat phyllosphere alkalinization, promoting the development of Fusarium head blight (FHB). Xu et al. show that host-acidifying Pseudomonas, selectively enriched in the wheat phyllosphere during F. graminearum invasion, counteract the pathogen-induced alkalinization through organic acid production, thereby suppressing FHB and emerging as effective biocontrol agents

"Keystone Pseudomonas species in the wheat phyllosphere microbiome mitigate Fusarium head blight by altering host pH" spkl.io/63323AdYmJ

#NanjingAgriculturalUniversity Wu Xiong, Xuewen Gao, Qin Gu & colleagues
@cp-cellhostmicrobe.bsky.social

(A) A female gelada with typical sex skin swellings surrounding her neck and chest region (credit: J Beehner). (B) Overview of female reproductive stages for the population mean (colored bars are proportional to the durations listed in Table 1).

"Evidence for deceptive fertility in a wild primate" spkl.io/63328AdYjO

@jbeehner.bsky.social & colleagues
@currentbiology.bsky.social

Taking programmed cell death from mechanisms to interventions

Together with our partners at Zhejiang University, Liangzhu Laboratory, we're thrilled to announce the Cell Symposium: Taking programmed cell death from mechanisms to interventions, taking place in Hangzhou, China, October 22–24, 2026
http://dlvr.it/TPMsG0
#CSCellDeath26

AI-powered integration of multimodal imaging in precision medicine for neuropsychiatric disorders

"AI-powered integration of multimodal imaging in precision medicine for neuropsychiatric disorders"
http://dlvr.it/TPMQnD

Ni Shu & Weijie Huang
@cp-cellrepmethods.bsky.social
#SfN2025

A functional perspective on astrocyte heterogeneity

"A functional perspective on astrocyte heterogeneity"
http://dlvr.it/TPML8T

Benjamin Deneen, Wookbong Kwon & @m-r-williamson.bsky.social
@cp-trendsneuro.bsky.social
#SfN2025

Starting a synthetic biological intelligence lab from scratch

"Starting a synthetic biological intelligence lab from scratch"
http://dlvr.it/TPMGGg

Mohammed A. Mostajo-Radji, Brett J. Kagan, Ge Wang & colleagues
@cp-patterns.bsky.social
#SfN2025

Cell Reports Methods

"An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons"
http://dlvr.it/TPM8Q9

Xiangmin Xu & colleagues
@cp-cellrepmethods.bsky.social
#SfN2025

STAR Protocols

"Protocol for reproducible EZ clearing and labeling, including optimized steps and quantified fluorescence retention on mouse tissue"
http://dlvr.it/TPM37Q

Ivana Gantar, Laura Batti & colleagues
@cp-protocols.bsky.social
#SfN2025