Esha Bandyopadhyay, Ph.D.

We will be at #ASHG25 this year! Some presentations from our group, please stop by! :

Excited to present my poster, “Tissue-Related Heterogeneity in Genetic Architecture of mtDNA Copy Number” (Board 5081), on Wednesday at #ASHG2025 !

Excited to be presenting my poster “Residual Stratification and Increased Genetic Diversity in Multi-ancestry GWAS”, Board 1062T on Thursday, October 16 from 2:30pm-4:30pm at #ASHG2025!

Homepage - 2026 Population, Evolutionary, and Quantitative Genetics Conference Visit our website to learn more.

PEQG website live! genetics-gsa.org/peqg-2026/

I want to try something again at #ASHG25 this year: I'll block some time on Thursday and Friday afternoons to meet with trainees who would be interested to chat on any topic.

I did this last year and it was great to meet a whole bunch of new people, at all career stages!

Inference of complex demographic history using composite likelihood based on whole-genome genealogies Accurate parametric inference on complex demographic models is a continuing challenge in population genetics. Ancestral recombination graphs (ARGs) provide richer information than simple population ge...

Excited to preprint our latest work (w/ Drew DeHaas, Zhibai Jia, Leo Speidel) on using ARGs for demographic inference. w/ applications using data from 1000 Genomes Project. www.biorxiv.org/content/10.1...

Postdoctoral position in Population Genomics - Uppsala University Postdoctoral position in Population Genomics, Department of Organismal Biology, Uppsala University

🚨 Join us in Uppsala and the lab of @trstngnthr.bsky.social as a 2 year fully funded bioinformatics postdoc with all Swedish social benefits etc!🧪

The project involves modern and #aDNA 🧬 in humans and sheep 🐑 to study adaptation. Application deadline: Oct 21st

www.uu.se/en/about-uu/...

Postdoctoral position in Population Genomics - Uppsala University Postdoctoral position in Population Genomics, Department of Organismal Biology, Uppsala University

I totally recommend this position on @trstngnthr.bsky.social lab. Great place to do science, and amazing people to do it with! #aDNA 🧪 www.uu.se/en/about-uu/...

We're organizing a new CARTA symposium this November 7 on "Ancient DNA: New Revelations"! We have an amazing lineup of speakers who will showcase the biggest discoveries in ancient DNA over the past 5 years - and offer a sneak peek of what's next. Mark your calendars and don't miss it!

Constraints on chromosome evolution revealed by the 229 chromosome pairs of the Atlas blue butterfly The genome of the Atlas blue butterfly contains ten times more chromosomes than most butterflies, and more than any other known diploid animal. Wright et al. show that this extraordinary karyotype is ...

How many chromosomes can an animal have?

In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Excited to say we’re hiring 😊. We’re looking for a post-doc in ancient pathogen genomics to join our friendly supportive team in London at @ugiatucl.bsky.social. Start date January 2026.

www.ucl.ac.uk/work-at-ucl/...

🚨JOB ALERT!🚨

Postdoc position at #CpgSthlm on Microtine Palaeogenomics!

Join our deep-time genomics project, funded by @erc.europa.eu, and help us explore lemming and vole evolution using ancient DNA from fossils spanning the last 2.6 million years 🐭🦴🧬

Apply here:
su.varbi.com/en/what:job/...

Columbian mammoth mitogenomes from Mexico uncover the species’ complex evolutionary history Paleogenomic studies suggest that Mammuthus columbi derives from an ancient hybridization between Mammuthus primigenius and Mammuthus trogontherii. While its habitat spanned from North to Central Amer...

Thrilled to share our study sequencing genetic data from tropical mammoths 🏝️🦣. First DNA recovered from Columbian mammoths southern than USA shorturl.at/xjIvy. Thanks to all collaborators, you were key to this success! See below a fantastic note covering the paper by the great @rpocisv.bsky.social 👇

Are you interested in doing a PhD in Copenhagen? Interested in studying Neanderthals and Denisovans which live on in our genomes?
Than you are more than welcome to apply to join my group starting Jan 2026 :)

candidate.hr-manager.net/ApplicationI...

Please reach out if you have any questions!

(Senior) Laboratory Research Scientist - Bioarchaeologist Salary for this Role: LRS level from £36,535 per annum plus benefits SLRS level from £45,700 per annum plus benefits Job Title: (Senior) Laboratory Research Scientist - Bioarchaeologist Reports to: Po...

Also - come and get my job! Which I’m still partially doing, but someone needs to take up the slack/ allow me to send them to far flung locations to retrieve mysterious ancient samples. See the World*!

*mainly Britain.

crick.wd3.myworkdayjobs.com/en-US/Extern...

Bioinformatician - Uppsala University Bioinformatician, Department of Organismal Biology, Uppsala University

The @scilifelab.se ancient DNA unit is looking for an bioinformatician placed at Uppsala University. This is a great way to be part of diverse #aDNA research projects as a staff scientist with permanent (!!) employment:

www.uu.se/en/about-uu/...

Accounting for Gene Flow from Unsampled Ghost Populations While Estimating Evolutionary History Abstract. Gene flow from unsampled or extinct ghost populations leave signatures on the genomes of individuals from extant, sampled populations, often intr

Oops - link appears to be broken. Try this: academic.oup.com/g3journal/ad...

MULTICLUST - Fast multinomial clustering of multiallelic genotypes to infer genetic population structure Identifying population structure from multilocus genotype data is key to downstream population genetic analyses in a variety of fields, including conservation, evolutionary genetics, Genome-Wide Assoc...

Excited for this to finally see the light of day - new preprint from my lab, where we present a fast, accurate maximum likelihood tool to estimate population structure, called MULTICLUST. We extend the model of Alexander et al 2009 (ADMIXTURE) to multiallelic data. www.biorxiv.org/content/10.1...

The spatiotemporal distribution of human pathogens in ancient Eurasia - Nature Screening shotgun-sequencing data from ancient humans covering 37,000 years of Eurasian history uncovers the widespread presence of ancient bacterial, viral and parasite DNA and zoonotic pathogens…

#MetagenomicsMonday Analysis of aDNA from 1313 ancient human remains spanning 37k years revealed that the rise of infectious diseases coincided with animal domestication around 65k years ago, with disease spread intensifying during pastoralist migrations.
www.nature.com/articles/s41...

Estimating allele frequencies, ancestry proportions and genotype likelihoods in the presence of mapping bias Abstract. Population genomic analyses rely on an accurate and unbiased characterization of the genetic composition of the studied population. For short-rea

Results of our (extremely long-term) side project with @amygoldberg.bsky.social and @jgschraiber.bsky.social out now in G3: doi.org/10.1093/g3jo...

We benchmarked methods for estimating ancestry proportions under mapping bias and present an adjusted GenotypeLikelihood to mitigate its impact (1/2)

New in #GENETICS: Huang et al. describe biases in SNP & local ancestry heritability as functions of admixture history and the genetic architecture of the trait, clarifying their interpretation and implication for #GWAS & polygenic prediction in population admixture.

Read more: buff.ly/1xB3Mpu

Re-upping this! @cegamorim.bsky.social and I are stoked to be offering this workshop. Do join us!

The mini yet mighty stapes: a comparison of ancient DNA yields among ossicles and the petrous bone The petrous bone is considered the most efficient source of endogenous DNA across skeletal tissues in ancient DNA research as well as in forensic work. Recently, ancient DNA (aDNA) in auditory ossicle...

New preprint alert 🚨
The tiniest bone in the human body appears to have the best DNA preservation: "The mini yet mighty staples"
www.biorxiv.org/content/10.1...

last day tomorrow to register for a talk/poster at Midwest popgen. Please RT(? is that what they say here?)!

Whole-genome ancestry of an Old Kingdom Egyptian - Nature Whole-genome sequencing of an ancient male Egyptian revealed a mixture of North African Neolithic and eastern Fertile Crescent ancestry, suggesting human migration between Egypt and Mesopotamia by the...

Forty years after Svante Pääbo kicked off this extraordinary field of science, today sees report of the first whole-genome sequence of an ancient Egyptian (from 2855–2570BCE). Exciting work from @pontus-skoglund.bsky.social, @flinklinus.bsky.social, & co at @ljmuofficial.bsky.social, @crick.ac.uk.🧬🧪

MWPG2025 Join us for the 10th Midwest Population Genetics conference, held at the University of Minnesota Twin Cities from August 21 - August 22, 2025.

Please register if you haven't already done so.
MidWest PopGen is happening in August at the University of Minnesota (Twin Cities)—abstract deadline for talk: July 11th, and poster: August 1st.

sites.google.com/umn.edu/mwpg...

Thrilled to see the latest work from the lab (@genscapelab.bsky.social) out in Current Biology! Congratulations @jaurban2204.bsky.social ! 🎉

Grateful to have had the chance to contribute to this effort.

Population histories of the Indigenous Adivasi and Sinhalese from Sri Lanka using whole genomes Sri Lanka is home to diverse ethnic groups with different genetic histories. Urban Aragon et al. find that despite close genetic affinities, Indigenous Adivasi have more hunter-gatherer ancestry and l...

Delighted to share that one of my major PhD projects has been published today in Current Biology.

In this paper, we look into the genetic population structure and demographic histories of two populations in Sri Lanka: the Sinhalese and Adivasi [1/n]. www.cell.com/current-biol...

Very special thanks to the Adivasi and Sinhalese individuals involved in this study!!! They are a pivotal part of this study, and we'll engage with them again in outreach activities soon! [6/n]
Special note: Some of the supplementary links are still being fixed by the journal!