Lori Passmore

Start independent research at the JIC with us 👇.

Really interested in finding those with an interest in structural biology and biochemistry of plants and microbes.

Please do get in touch by email if you'd like to know more 👍

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

Oh that’s not what I meant at all. Family obligations are always a juggle. It is especially challenging in summer for many reasons - including for those who have (often aging) family overseas.

Just a reminder that August is peak school holidays in the UK, but also more broadly in Europe and in Canada. If you schedule conferences during August you exclude a large proportion of people from these regions who have family obligations.

depmap miner logo

The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data!
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.

Start mining data now: dataminer.depmap.sanger.ac.uk

We are hiring-join us!

Just one more week left to get an application in! Starting my lab at the Perutz and the @viennabiocenter.bsky.social has been a fantastic opportunity that shaped me as a scientist!

Great start to the EMBL translation control meeting with a keynote from @lapassmore.bsky.social. Excited for all the science to come. #EMBLProtein

Group Leader Career Development Fellowships - Dunn School Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?

Are you a postdoc interested in the mechanisms of disease?

Do you have a great record and an exciting vision?

Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.

Deadline 30th September...pass it on!

www.path.ox.ac.uk/work-with-us...

Congratulations Bronwyn and team!!

We LOVE the brewer palette!
Imported into illustrator to facilitate figure making in my lab.

Unprompted, the 14yo told me she has a deep hatred for Comic Sans.
I love that kid so much.

Fantastic talk by Ethan showcasing our work with @lapassmore.bsky.social lab at @cshlmeetings.bsky.social #RNAPR25! Hurray Ethan!

⏰Early Bird and Talk Submission Deadline closing soon - Tuesday 26th August 2025
📣Don’t miss your chance to be part of the amazing #DRRSC26 meeting.
👉 Click here for further details & registration: bit.ly/46YQZjW

Congratulations to @bcarrick.bsky.social on his Shurl and Kay Curci Fellowship through the Life Sciences Research Foundation! Looking forward to the work to come!

Excited to share our latest work! We found transcription factor SPT6 and phosphorylated Pol II CTD help recruit U1 snRNP to elongating Pol II, allowing efficient co-transcriptional splicing.

Glad to be featured in the Editors’ Highlights!

www.nature.com/articles/s41...

#splicing #cryoEM

Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization Telomerase ribonucleoprotein (RNP) synthesizes telomeric repeats at chromosome ends using a telomerase reverse transcriptase (TERT) and a telomerase RNA (hTR in humans). Previous structural work showe...

Proud to share our work where we resolved a longstanding question regarding the existence of a human telomerase dimer and provided insights into its function. Led by 3 amazing lab members in collaboration with @yiliangding.bsky.social and @rdaslab.bsky.social.
www.science.org/doi/10.1126/...

📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Molecular Mechanisms of Disease. More information ➡️ tinyurl.com/3yn883b8

Thank you David, Wei and @fusionconf.bsky.social for lots of nucleic acid science!! 🧬🎉🧬🎉🧬

Leo James, Greg Jefferis and Marta Zlatic

Congratulations to LMB Group Leaders Leo James, Greg Jefferis & Marta Zlatic who have been elected Fellows of the @royalsociety.org!

Congratulations also to the #LMBAlumni joining them: John Briggs, Graham Hatfull & Baljit Khakh.

Read more: www2.mrc-lmb.cam.ac.uk/leo-james-gr...

#LMBNews

A collage of nine faces making up the nine members of Cambridge University who have been elected as Fellows of the Royal Society

Congratulations to the nine outstanding Cambridge scientists who have been elected as Fellows of the @royalsociety.org, the UK’s national academy of sciences and the oldest science academy in continuous existence.

Explore their research 👉 www.cam.ac.uk/research/new...

#CambridgeUniversity

Come and join us! We’re hiring a new Group Leader in Generative Biology at the @sangerinstitute.bsky.social

Building AI models or the data to train them?

Core funding of >$130M a year for a faculty of ~30.

www.nature.com/naturecareer...

acrobat.adobe.com/id/urn:aaid:...

pls RT!

A kinetic ruler controls mRNA poly(A) tail length Poly(A) tails of newly synthesized mRNAs have uniform lengths, arising through cooperation between the cleavage and polyadenylation complex (CPAC) and poly(A) binding proteins (PABPs). In the budding ...

New work from Matti Turtola showing that mRNA poly(A) tail length is controlled by a kinetic ruler. A real pleasure to work with him!
www.biorxiv.org/content/10.1...

New abstract deadline May 8, 2025. Should be a great meeting!!

Voting by mail – Elections Canada Apply to vote by mail, Eligible electors can apply to vote by special ballot. With a special ballot, you can vote by mail from anywhere in the world, 2025.

Canadians 🇨🇦 abroad - you can register to vote in the election! You need to do it soon. www.elections.ca/content2.asp...

New Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. www.grc.org/synthetic-le....

Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.

Just a reminder that our tenure track group leader position in the Structural Studies Division of @mrclmb.bsky.social will close in four days!

mrc.tal.net/vx/lang-en-G...

SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
 
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).

www.embl.org/about/info/c...

I see a "Free Full Text" bar that expands out to full text - see attached.

Hmm, I checked a few papers and I can see the PMC free text on the EuropePMC page, e.g. europepmc.org/article/MED/...