Jakub Zeman's Avatar

Jakub Zeman

@jakub-zeman.bsky.social

Postdoc with interest in ribosomes, proteins, cardiomyocytes, human embryonic cell fate... ...cats, investing, and sarcasm.

123 Followers  |  140 Following  |  53 Posts  |  Joined: 09.12.2023  |  2.1401

Latest posts by jakub-zeman.bsky.social on Bluesky

A table showing profit margins of major publishers. A snippet of text related to this table is below.

1. The four-fold drain
1.1 Money
Currently, academic publishing is dominated by profit-oriented, multinational companies for
whom scientific knowledge is a commodity to be sold back to the academic community who
created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis,
which collectively generated over US$7.1 billion in revenue from journal publishing in 2024
alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit
margins have always been over 30% in the last five years, and for the largest publisher
(Elsevier) always over 37%.
Against many comparators, across many sectors, scientific publishing is one of the most
consistently profitable industries (Table S1). These financial arrangements make a substantial
difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor &
Francis revenues were generated in North America, meaning that North American
researchers were charged over US$2.27 billion by just two for-profit publishers. The
Canadian research councils and the US National Science Foundation were allocated US$9.3
billion in that year.

A table showing profit margins of major publishers. A snippet of text related to this table is below. 1. The four-fold drain 1.1 Money Currently, academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis, which collectively generated over US$7.1 billion in revenue from journal publishing in 2024 alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit margins have always been over 30% in the last five years, and for the largest publisher (Elsevier) always over 37%. Against many comparators, across many sectors, scientific publishing is one of the most consistently profitable industries (Table S1). These financial arrangements make a substantial difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor & Francis revenues were generated in North America, meaning that North American researchers were charged over US$2.27 billion by just two for-profit publishers. The Canadian research councils and the US National Science Foundation were allocated US$9.3 billion in that year.

A figure detailing the drain on researcher time.

1. The four-fold drain

1.2 Time
The number of papers published each year is growing faster than the scientific workforce,
with the number of papers per researcher almost doubling between 1996 and 2022 (Figure
1A). This reflects the fact that publishers’ commercial desire to publish (sell) more material
has aligned well with the competitive prestige culture in which publications help secure jobs,
grants, promotions, and awards. To the extent that this growth is driven by a pressure for
profit, rather than scholarly imperatives, it distorts the way researchers spend their time.
The publishing system depends on unpaid reviewer labour, estimated to be over 130 million
unpaid hours annually in 2020 alone (9). Researchers have complained about the demands of
peer-review for decades, but the scale of the problem is now worse, with editors reporting
widespread difficulties recruiting reviewers. The growth in publications involves not only the
authors’ time, but that of academic editors and reviewers who are dealing with so many
review demands.
Even more seriously, the imperative to produce ever more articles reshapes the nature of
scientific inquiry. Evidence across multiple fields shows that more papers result in
‘ossification’, not new ideas (10). It may seem paradoxical that more papers can slow
progress until one considers how it affects researchers’ time. While rewards remain tied to
volume, prestige, and impact of publications, researchers will be nudged away from riskier,
local, interdisciplinary, and long-term work. The result is a treadmill of constant activity with
limited progress whereas core scholarly practices – such as reading, reflecting and engaging
with others’ contributions – is de-prioritized. What looks like productivity often masks
intellectual exhaustion built on a demoralizing, narrowing scientific vision.

A figure detailing the drain on researcher time. 1. The four-fold drain 1.2 Time The number of papers published each year is growing faster than the scientific workforce, with the number of papers per researcher almost doubling between 1996 and 2022 (Figure 1A). This reflects the fact that publishers’ commercial desire to publish (sell) more material has aligned well with the competitive prestige culture in which publications help secure jobs, grants, promotions, and awards. To the extent that this growth is driven by a pressure for profit, rather than scholarly imperatives, it distorts the way researchers spend their time. The publishing system depends on unpaid reviewer labour, estimated to be over 130 million unpaid hours annually in 2020 alone (9). Researchers have complained about the demands of peer-review for decades, but the scale of the problem is now worse, with editors reporting widespread difficulties recruiting reviewers. The growth in publications involves not only the authors’ time, but that of academic editors and reviewers who are dealing with so many review demands. Even more seriously, the imperative to produce ever more articles reshapes the nature of scientific inquiry. Evidence across multiple fields shows that more papers result in ‘ossification’, not new ideas (10). It may seem paradoxical that more papers can slow progress until one considers how it affects researchers’ time. While rewards remain tied to volume, prestige, and impact of publications, researchers will be nudged away from riskier, local, interdisciplinary, and long-term work. The result is a treadmill of constant activity with limited progress whereas core scholarly practices – such as reading, reflecting and engaging with others’ contributions – is de-prioritized. What looks like productivity often masks intellectual exhaustion built on a demoralizing, narrowing scientific vision.

A table of profit margins across industries. The section of text related to this table is below:

1. The four-fold drain
1.1 Money
Currently, academic publishing is dominated by profit-oriented, multinational companies for
whom scientific knowledge is a commodity to be sold back to the academic community who
created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis,
which collectively generated over US$7.1 billion in revenue from journal publishing in 2024
alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit
margins have always been over 30% in the last five years, and for the largest publisher
(Elsevier) always over 37%.
Against many comparators, across many sectors, scientific publishing is one of the most
consistently profitable industries (Table S1). These financial arrangements make a substantial
difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor &
Francis revenues were generated in North America, meaning that North American
researchers were charged over US$2.27 billion by just two for-profit publishers. The
Canadian research councils and the US National Science Foundation were allocated US$9.3
billion in that year.

A table of profit margins across industries. The section of text related to this table is below: 1. The four-fold drain 1.1 Money Currently, academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis, which collectively generated over US$7.1 billion in revenue from journal publishing in 2024 alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit margins have always been over 30% in the last five years, and for the largest publisher (Elsevier) always over 37%. Against many comparators, across many sectors, scientific publishing is one of the most consistently profitable industries (Table S1). These financial arrangements make a substantial difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor & Francis revenues were generated in North America, meaning that North American researchers were charged over US$2.27 billion by just two for-profit publishers. The Canadian research councils and the US National Science Foundation were allocated US$9.3 billion in that year.

The costs of inaction are plain: wasted public funds, lost researcher time, compromised
scientific integrity and eroded public trust. Today, the system rewards commercial publishers
first, and science second. Without bold action from the funders we risk continuing to pour
resources into a system that prioritizes profit over the advancement of scientific knowledge.

The costs of inaction are plain: wasted public funds, lost researcher time, compromised scientific integrity and eroded public trust. Today, the system rewards commercial publishers first, and science second. Without bold action from the funders we risk continuing to pour resources into a system that prioritizes profit over the advancement of scientific knowledge.

We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing:

a 🧵 1/n

Drain: arxiv.org/abs/2511.04820
Strain: direct.mit.edu/qss/article/...
Oligopoly: direct.mit.edu/qss/article/...

11.11.2025 11:52 — 👍 608    🔁 435    💬 8    📌 62
Post image

A small book, big truths.

23.10.2025 16:44 — 👍 1    🔁 0    💬 0    📌 0
Post image

@svobodalab.bsky.social This one is for you!

30.09.2025 21:50 — 👍 4    🔁 0    💬 0    📌 0

“Just because you are offended doesn’t mean you are right.”
Ricky Gervais

15.09.2025 13:19 — 👍 1    🔁 0    💬 0    📌 0

Our new preprint, full of exciting data, is now available. Have a look!

QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5ʹ splice sites
www.biorxiv.org/content/10.1...

08.09.2025 06:32 — 👍 3    🔁 0    💬 0    📌 0

Což, pokud si dobře pamatuju, bylo jeho jediné („)štěstí(“), protože opylování hrachu představeným nevadilo tak, jako obcování myší mezi zdmi kláštera.

21.08.2025 11:39 — 👍 1    🔁 0    💬 1    📌 0
Preview
SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress SPIDR, a massively multiplexed method that simultaneously maps dozens of RNA-binding proteins to their RNA targets at single-nucleotide resolution, uncovers new RNA-protein interactions and provides c...

www.cell.com/cell/fulltex...

Tour de force spearheaded by brilliant Marko Jovanovic and colleagues!

23.07.2025 04:47 — 👍 13    🔁 2    💬 0    📌 0
Post image

An Optimized SP3 Sample Processing Workflow for In-Depth and Reproducible Phosphoproteomics pubs.acs.org/doi/10....

---
#proteomics #prot-paper

18.07.2025 19:20 — 👍 3    🔁 2    💬 0    📌 0
Preview
Mini hearts, lungs and livers made in lab now grow their own blood vessels These sophisticated models will be used for human-development studies and drug testing.

Researchers are making ever more sophisticated mini organs in the lab — and now they can grow their own blood vessels

go.nature.com/4nNF3ri

11.07.2025 11:12 — 👍 53    🔁 15    💬 1    📌 2

My point is that Illustrator is not meant for assembling multi-page figures full of different types of files and text, yet people use it for that purpose, just because it’s somehow possible.

09.07.2025 16:05 — 👍 0    🔁 0    💬 0    📌 0

Creating charts, models, labelled WB images… and assembling them into figures are two different problems. 🤔

09.07.2025 15:45 — 👍 0    🔁 0    💬 1    📌 0

One day, scientists will discover Adobe InDesign/Affinity Publisher/… for figure assembly and our lives will be much easier…

09.07.2025 11:01 — 👍 1    🔁 0    💬 1    📌 0

A review of the history of protein-RNA friendship.

09.07.2025 10:54 — 👍 2    🔁 0    💬 0    📌 0

Germany of the 21st century: A place where there is a massive problem for all major personal parcel delivery companies to deliver an order.
#OrdnungMussSein

04.07.2025 13:29 — 👍 0    🔁 0    💬 0    📌 0

Feedback without specifics is not feedback. It’s frustration.

03.07.2025 09:49 — 👍 1    🔁 0    💬 1    📌 0
Post image

'Night science' is what you do when you're not sure what's the question.

03.07.2025 08:17 — 👍 33    🔁 9    💬 0    📌 2
A painting of a bird next to the words "I'm gonna need a moment to process this bullshit"

A painting of a bird next to the words "I'm gonna need a moment to process this bullshit"

15.06.2025 14:08 — 👍 516    🔁 73    💬 2    📌 7
Post image

Dream big. Dare to fail. Fuck dull, incremental science.

02.07.2025 14:49 — 👍 3    🔁 0    💬 0    📌 0
Preview
Open positions We are looking for Postdocs! If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …

We have several open postdoc positions! We do computational biology 🧬🖥️ and deep learning to understand the genomics of genome instability and (somatic) genome evolution in ageing and cancer. Interested? 👉🏻 more details: tu-dresden.de/cmcb/biotec/...

26.06.2025 09:46 — 👍 9    🔁 6    💬 1    📌 0
Traffic Jam without bottleneck - experimental evidence
YouTube video by Francis Villatoro Traffic Jam without bottleneck - experimental evidence

Ribosomes on an mRNA molecule are like:

youtu.be/7wm-pZp_mi0?...

26.06.2025 05:52 — 👍 2    🔁 0    💬 0    📌 0
Post image Post image

I visited the lab where I did my PhD today. They moved two floors upstairs since I left in 2020, they have got new stuff, many new students and postdocs. Yet, there are still boxes with my name around, and they are about to finish the 3C protease I purified back then. 🧡 #ProteinPutification #eIF3

19.06.2025 15:05 — 👍 4    🔁 0    💬 1    📌 0
Post image 19.06.2025 10:14 — 👍 3    🔁 1    💬 0    📌 0
Post image

Every. Time.

17.06.2025 16:09 — 👍 4    🔁 0    💬 0    📌 0

Life is hell sometimes!

17.06.2025 08:45 — 👍 3    🔁 0    💬 0    📌 0
Post image

- Return to work after attending #TCTeAC
- Make yourself a cappuccino
- Reflect on all the wonderful things in life
- Clear out those emails and embrace happiness

16.06.2025 10:29 — 👍 12    🔁 0    💬 0    📌 0
Post image

The following day after coming back from #TCTeAC

15.06.2025 08:55 — 👍 7    🔁 0    💬 0    📌 0

If any #TCTeAC survivors are staying in Prague tonight or longer, feel free to DM me for recommendations, tricks, and survival tips. Or we can have a last beer together this evening.
#AllRoadsLeadToPub

13.06.2025 12:51 — 👍 6    🔁 1    💬 0    📌 0

😂

13.06.2025 12:45 — 👍 0    🔁 0    💬 0    📌 0
Post image

#TCTeAC ... and that was all, folks! Thank you, it was fantastic.

13.06.2025 08:33 — 👍 59    🔁 6    💬 1    📌 1

@jakub-zeman is following 20 prominent accounts