Jakub Zeman

SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress SPIDR, a massively multiplexed method that simultaneously maps dozens of RNA-binding proteins to their RNA targets at single-nucleotide resolution, uncovers new RNA-protein interactions and provides c...

www.cell.com/cell/fulltex...

Tour de force spearheaded by brilliant Marko Jovanovic and colleagues!

An Optimized SP3 Sample Processing Workflow for In-Depth and Reproducible Phosphoproteomics pubs.acs.org/doi/10....

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#proteomics #prot-paper

Mini hearts, lungs and livers made in lab now grow their own blood vessels These sophisticated models will be used for human-development studies and drug testing.

Researchers are making ever more sophisticated mini organs in the lab — and now they can grow their own blood vessels

go.nature.com/4nNF3ri

My point is that Illustrator is not meant for assembling multi-page figures full of different types of files and text, yet people use it for that purpose, just because it’s somehow possible.

Creating charts, models, labelled WB images… and assembling them into figures are two different problems. 🤔

One day, scientists will discover Adobe InDesign/Affinity Publisher/… for figure assembly and our lives will be much easier…

A review of the history of protein-RNA friendship.

Germany of the 21st century: A place where there is a massive problem for all major personal parcel delivery companies to deliver an order.
#OrdnungMussSein

Feedback without specifics is not feedback. It’s frustration.

'Night science' is what you do when you're not sure what's the question.

A painting of a bird next to the words "I'm gonna need a moment to process this bullshit"

Dream big. Dare to fail. Fuck dull, incremental science.

Open positions We are looking for Postdocs! If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …

We have several open postdoc positions! We do computational biology 🧬🖥️ and deep learning to understand the genomics of genome instability and (somatic) genome evolution in ageing and cancer. Interested? 👉🏻 more details: tu-dresden.de/cmcb/biotec/...

YouTube video by Francis Villatoro Traffic Jam without bottleneck - experimental evidence

Ribosomes on an mRNA molecule are like:

youtu.be/7wm-pZp_mi0?...

I visited the lab where I did my PhD today. They moved two floors upstairs since I left in 2020, they have got new stuff, many new students and postdocs. Yet, there are still boxes with my name around, and they are about to finish the 3C protease I purified back then. 🧡 #ProteinPutification #eIF3

Every. Time.

Life is hell sometimes!

- Return to work after attending #TCTeAC
- Make yourself a cappuccino
- Reflect on all the wonderful things in life
- Clear out those emails and embrace happiness

The following day after coming back from #TCTeAC

If any #TCTeAC survivors are staying in Prague tonight or longer, feel free to DM me for recommendations, tricks, and survival tips. Or we can have a last beer together this evening.
#AllRoadsLeadToPub

😂

#TCTeAC ... and that was all, folks! Thank you, it was fantastic.

One of the last pictures of @dalibormiklik.bsky.social before his life was changed forever by attending the Barkley Marathon - Soběšín edition.

The fewer charts, the more interest. 🤔
I am grateful to everyone who stopped by my poster and discussed the cell fate decisions and cardiac differentiation with me.
#AffinityDesigner
#ThePosterToEndAllPosters
#TCTeAC

We all secretly want to be Adam. But for more design, follow me—Jakub, Adam’s fill-in. 🙂

#TCTeAC

A level of happiness that is typically only seen in beer commercials.

People at #TCTeAC recognise me for taking speakers off the stage now.
But there’s more (less?!) to come. Stay tuned! Poster 57.

@odedrechavi.bsky.social says he wants to change science for the better.

How? I’m still not quite sure. But 1.5 days into #TCTeAC, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.