EvodevogenomeUB- Cañestro’s lab

Feliç diada!! Happy Catalonian day!!
Today, we celebrate the national day of Catalonia, …and one of the typical things we eat today is the “Bread of Saint Jordi” (top), that clearly resembles “something” known by all biologists 😅
💛❤️💛❤️💛❤️💛❤️💛🔬🧬🪰

Wow, Josep!!! So exciting!! Happy to see you back to (north) Catalonia!! Congrats!!

Congrats Esteve 👏🏻👏🏻 for your excellent defense of your TFG studying how marine noise contamination affects #Oikopleura, #deuteronoise project cosupervised by @evadevo.bsky.social @esteeve.bsky.social @geneticsub.bsky.social @irbio-ub.bsky.social @ub.edu

@criscanestro.bsky.social gives a lovely, thoughtful talk on this theme, on a tunicate species with very a scrambled genome; then reflects on what the patterns of scrambling can tell us about the underlying regulatory architecture. #eseb2025

Thanks @jmolev.bsky.social !! For more on our science, please follow us here at @evodevogenomeub.bsky.social

How the Pygmy Sea Horse Lost Its Snout

✒️ Don't miss @carlzimmer.com’s article in @nytimes.com, on the impact of gene loss in pygmy seahorses, featuring insights from Cristian Cañestro @evodevogenomeub.bsky.social @geneticsub.bsky.social

🔗 www.nytimes.com/2025/08/25/s...

Beautiful piece by @carlzimmer.com about the impact of #GeneLoss on pygmy sea horses. Thrilled to see Cañestro’s comments mentioned in @nytimes.com. This does not happen everyday! Thanks, Carl☺️

@criscanestro.bsky.social @geneticsub.bsky.social @irbio-ub.bsky.social @biologiaub.bsky.social @ub.edu

Great contributions of our lab in #ESEB2025 with our research on genome architecture and gene regulation from an #oikopleura perspective.
Great organization
@eseb2025.bsky.social @tonigabaldon.bsky.social @ntorresag.bsky.social @geneticsub.bsky.social @irbio-ub.bsky.social @biologiaub.bsky.social

Today in #FestaCiènciaUB we are sharing the progress of our @deuteronoise project JPI studying how marine noise pollution affects embryo development of marine invertebrates. Great work @evadevo.bsky.social in collaboration lasalle’s group of Dra. RosaM Alsina & Ignasi Nou
@ubdivulga.bsky.social

Avui i demà el nostre grup @geneticsub.bsky.social @irbio-ub.bsky.social participa a #FestaCiènciaUB compartint amb els infants el que fem al laboratori i promovent les seves ganes d’investigar i descobrir els enigmes que la natura ens ofereix. Gràcies @ubdivulga.bsky.social per organitzar-ho!

Un mar de problemes - La UB Divulga - UB Taller de la XI Festa de la Ciència de la Universitat de Barcelona.

Despertem a la #FestaCiènciaUB la consciència sobre la contaminació marina que pateixen els nostres mars i oceans 🌊 a través de l'observació de criatures marines 🔎 web.ub.edu/ca/web/laubd... @evodevogenomeub.bsky.social @geneticsub.bsky.social @irbio-ub.bsky.social @biologiaub.bsky.social

#Genètica | Llegim a @es.theconversation.com  aquest article del @criscanestro.bsky.social  i el @gasparsanchez.bsky.social 
➡️ Menos, pero más: entendiendo la pérdida de genes en la evolución.
🔗 https://theconversation.com/menos-pero-mas-entendiendo-la-perdida-de-genes-en-la-evolucion-249961

Moltes gràcies @biolegscat.bsky.social per fer-vo-en eco de la notícia sobre la recerca del nostre grup. Ancorat adalt al nostre fil trobareu un bluetutorial🦋 per qui vulgui llegir una mica més sobre la rellevància de la “pèrdua gènica” i la hipòtesis “menys, però més” 🧬🔬🌊

Publication of our outreach article on our work on #GeneLoss "Less, but more" studying #Fgf #evolution in #Oikopleura @gasparsanchez.bsky.social @geneticsub.bsky.social
@es.theconversation.com
Thanks Laura for your great editorial work @lauragderivera.bsky.social
theconversation.com/menos-pero-m...

Escola Miquel Marti i Pol de Viladecans Científiques, UB-divulga

Institut Vinyes Velles Montornés del Vallés Camins infinitits

Proud of the two amazing women of our lab, @ntorresag.bsky.social @evadevo.bsky.social, who in the Int. Day of Women and Girls in Science went to two schools to talk about their projects and become models for girls and boys to follow 👩‍🔬 #11FdoneSTEMub @ubdivulga.bsky.social @geneticsub.bsky.social

@tinosaurio.bsky.social Constantino’s poster, CRISPR and chill 🤩

Great talk by Nuria @ntorresag.bsky.social on her postdoctoral research in our lab studying how marine biotoxins affects gene expression & chromatin remodelling in Oikopleura embryos, in colaboration with @mariarossello.bsky.social at @geneticsub.bsky.social @irbio-ub.bsky.social @scb.iec.cat

Today, do not miss the posters of our lab at @geneticsub.bsky.social @irbio-ub.bsky.social working in (Eco)EvoDevo using Oikopleura as a model. #Noisosome @evadevo.bsky.social #GenomeScrambling @baielx.bsky.social #CRISPR @tinosaurio.bsky.social

Dioicous new year!! 🍾🥂
Our lab wish you a very free-living 2025!!🥳🥳
Artist 🤩: @tinosaurio.bsky.social

Thanks, here you can find a #Bluetorial of our article on “Less, but more” evolution
👇🏻
bsky.app/profile/evod...

Less, but more: new insights from appendicularians on chordate Fgf evolution and the divergence of tunicate lifestyles https://pubmed.ncbi.nlm.nih.gov/39686543/

Congrats 🥳🥳 @ntorresag.bsky.social and @mariarossello.bsky.social for being granted with this exciting projects as PIs studying gene regulatory landscape in scramble genomes at #SGREvoDevoCat

#EvoDevo and #Genomics rock 🧬🎸🤘🏻😎

@geneticsub.bsky.social @irbio-ub.bsky.social @biologiaub.bsky.social

Thanks to funders: Ministerio de Ciencia, Innovación y Universidades of Spain, ICREA-Academia program and SGR from AGAUR-Generalitat de Catalunya. Thanks to all our colleagues from OIST, and support from our instititution @geneticsub.bsky.social @irbio-ub.bsky.social @biologiaub.bsky.social @ub.edu

These findings can be useful to better understand the adaptive impact of gene loss on the evolution and diversification of species across the tree of life.

In conclussion, the "LESS, but MORE" evolutionary scenario illustrated in this work expands the "LESS is MORE" hypothesis by helping to recognize patterns of evolution associated with the cooccurrence of extensive gene losses and duplications.

Our results reveal differences in gene structure and splice isoforms among Fgf genes of O. dioica from different locations in the world, providing the first molecular evidence of how these fast evolving populations are becoming cryptic species.

Our results points to the Fgf11/12/13/14 as an evolutionary innovation of the olfactores (absent in amphioxus). The shared presence of N-term alternative splicings, which are associated to neuron excitability modulation, is interesting to develop new animal models related to human neuronal disorders

The two surviving subfamilies Fgf9/16/20 and Fgf11/12/13/14 in appendicularians might represent the "minimal Fgf subfamily repertoire" in olfactores, and the fact that they play secreting and intracellular functions, respectively, provides important insights into the evolvability of the Fgf system.

The generation of an Anterior Tail Fgf Source (ATFS) might be connected to the loss of the retinoic acid (RA) signaling in appendicularians, which is especially relevant considering the conserved antagonistic role that Fgf and RA play in the development of the body plan in ascidians and vertebrates.